Aliases for USP40 Gene
External Ids for USP40 Gene
Previous GeneCards Identifiers for USP40 Gene
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008]
GeneCards Summary for USP40 Gene
USP40 (Ubiquitin Specific Peptidase 40) is a Protein Coding gene. Among its related pathways are Ubiquitin-Proteasome Dependent Proteolysis. Gene Ontology (GO) annotations related to this gene include cysteine-type endopeptidase activity and thiol-dependent ubiquitin-specific protease activity. An important paralog of this gene is USP47.
UniProtKB/Swiss-Prot for USP40 Gene
May be catalytically inactive.