Free for academic non-profit institutions. Other users need a Commercial license
USP32 (Ubiquitin Specific Peptidase 32) is a Protein Coding gene. Among its related pathways are Ubiquitin-Proteasome Dependent Proteolysis. Gene Ontology (GO) annotations related to this gene include calcium ion binding and thiol-dependent ubiquitin-specific protease activity. An important paralog of this gene is USP6.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004843 | thiol-dependent ubiquitin-specific protease activity | IBA,IDA | 20549504 |
GO:0005509 | calcium ion binding | IEA | -- |
GO:0005515 | protein binding | IPI | 24705354 |
GO:0008233 | peptidase activity | IEA | -- |
GO:0008234 | cysteine-type peptidase activity | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005794 | Golgi apparatus | IBA,IDA | 20549504 |
GO:0005829 | cytosol | IDA | -- |
GO:0016020 | membrane | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Ubiquitin-Proteasome Dependent Proteolysis |
Ubiquitin-Proteasome Dependent Proteolysis
-
|
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006508 | proteolysis | IEA | -- |
GO:0006511 | ubiquitin-dependent protein catabolic process | IEA | -- |
GO:0016579 | protein deubiquitination | TAS | 20549504 |
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Water | Approved | Pharma | 0 |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | USP32 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | -- 31 |
|
OneToMany | |
USP32 30 |
|
||||
Cow (Bos Taurus) |
Mammalia | -- 31 |
|
OneToMany | |
USP32 30 |
|
||||
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
Mouse (Mus musculus) |
Mammalia | Usp32 30 17 31 |
|
OneToMany | |
Rat (Rattus norvegicus) |
Mammalia | Usp32 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
Chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
USP32 30 |
|
||||
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | usp32 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | usp32 30 31 |
|
OneToMany | |
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP001209 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG8334 30 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | cyk-3 30 |
|
||
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | UBP12 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
No disorders were found for USP32 Gene.