Aliases for USP3 Gene
External Ids for USP3 Gene
Previous GeneCards Identifiers for USP3 Gene
GeneCards Summary for USP3 Gene
USP3 (Ubiquitin Specific Peptidase 3) is a Protein Coding gene. Among its related pathways are Deubiquitination and Ubiquitin-Proteasome Dependent Proteolysis. Gene Ontology (GO) annotations related to this gene include chromatin binding and cysteine-type endopeptidase activity. An important paralog of this gene is USP4.
UniProtKB/Swiss-Prot Summary for USP3 Gene
Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.