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Aliases for USP17L7 Gene

Aliases for USP17L7 Gene

  • Ubiquitin Specific Peptidase 17-Like Family Member 7 2 3 5
  • Ubiquitin Specific Peptidase 17-Like 7 2 3
  • Inactive Ubiquitin Carboxyl-Terminal Hydrolase 17-Like Protein 7 3

External Ids for USP17L7 Gene

Previous GeneCards Identifiers for USP17L7 Gene

  • GC08M012030
  • GC08M011990

Summaries for USP17L7 Gene

GeneCards Summary for USP17L7 Gene

USP17L7 (Ubiquitin Specific Peptidase 17-Like Family Member 7) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include thiol-dependent ubiquitinyl hydrolase activity. An important paralog of this gene is USP17L8.

Additional gene information for USP17L7 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for USP17L7 Gene

Genomics for USP17L7 Gene

GeneHancer (GH) Regulatory Elements for USP17L7 Gene

Top Transcription factor binding sites by QIAGEN in the USP17L7 gene promoter:
  • C/EBPbeta
  • COUP
  • COUP-TF1
  • HNF-4alpha1
  • HNF-4alpha2
  • HTF
  • FOXF2
  • ATF-2

Genomic Locations for USP17L7 Gene

Genomic Locations for USP17L7 Gene
2,022 bases
Minus strand
2,028 bases
Minus strand

Genomic View for USP17L7 Gene

Genes around USP17L7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
USP17L7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for USP17L7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for USP17L7 Gene

Proteins for USP17L7 Gene

  • Protein details for USP17L7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7
    Protein Accession:

    Protein attributes for USP17L7 Gene

    530 amino acids
    Molecular mass:
    59751 Da
    Quaternary structure:
    No Data Available

neXtProt entry for USP17L7 Gene

Post-translational modifications for USP17L7 Gene

No Post-translational modifications

Other Protein References for USP17L7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for USP17L7 Gene

Domains & Families for USP17L7 Gene

Gene Families for USP17L7 Gene

Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins

Protein Domains for USP17L7 Gene


Suggested Antigen Peptide Sequences for USP17L7 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the peptidase C19 family. USP17 subfamily.
  • Belongs to the peptidase C19 family. USP17 subfamily.
genes like me logo Genes that share domains with USP17L7: view

Function for USP17L7 Gene

Gene Ontology (GO) - Molecular Function for USP17L7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA --
genes like me logo Genes that share ontologies with USP17L7: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for USP17L7 Gene

Localization for USP17L7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for USP17L7 Gene

Nucleus. Endoplasmic reticulum.

Gene Ontology (GO) - Cellular Components for USP17L7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005783 endoplasmic reticulum IEA --
genes like me logo Genes that share ontologies with USP17L7: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for USP17L7 Gene

Pathways & Interactions for USP17L7 Gene

SuperPathways for USP17L7 Gene

No Data Available

Interacting Proteins for USP17L7 Gene

Gene Ontology (GO) - Biological Process for USP17L7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006511 ubiquitin-dependent protein catabolic process IEA --
GO:0016579 protein deubiquitination IEA --
genes like me logo Genes that share ontologies with USP17L7: view

No data available for Pathways by source and SIGNOR curated interactions for USP17L7 Gene

Drugs & Compounds for USP17L7 Gene

No Compound Related Data Available

Transcripts for USP17L7 Gene

mRNA/cDNA for USP17L7 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for USP17L7 Gene

Ubiquitin specific peptidase 17-like family member 7:
Representative Sequences:

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for USP17L7 Gene

No ASD Table

Relevant External Links for USP17L7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for USP17L7 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for USP17L7 Gene

NURSA nuclear receptor signaling pathways regulating expression of USP17L7 Gene:


SOURCE GeneReport for Unigene cluster for USP17L7 Gene:

genes like me logo Genes that share expression patterns with USP17L7: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for USP17L7 Gene

Orthologs for USP17L7 Gene

Evolution for USP17L7 Gene

Gene Tree for USP17L7 (if available)
Gene Tree for USP17L7 (if available)

No data available for Orthologs for USP17L7 Gene

Paralogs for USP17L7 Gene

Variants for USP17L7 Gene

Sequence variations from dbSNP and Humsavar for USP17L7 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1006694004 -- 12,132,654(-) G/A coding_sequence_variant, synonymous_variant
rs1011227128 -- 12,134,667(-) C/A upstream_transcript_variant
rs1011427817 -- 12,135,932(-) C/T upstream_transcript_variant
rs1021219219 -- 12,134,703(-) A/G/T upstream_transcript_variant
rs1034717681 -- 12,134,633(-) C/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for USP17L7 Gene

Variant ID Type Subtype PubMed ID
dgv11959n54 CNV loss 21841781
dgv11960n54 CNV gain 21841781
dgv11961n54 CNV loss 21841781
dgv11962n54 CNV loss 21841781
dgv11963n54 CNV loss 21841781
dgv11964n54 CNV loss 21841781
dgv1270e199 CNV deletion 23128226
dgv154e203 CNV gain+loss 21179565
dgv244e55 CNV gain 17911159
dgv27n31 CNV gain 19718026
dgv7015n100 CNV gain 25217958
dgv7016n100 CNV gain 25217958
dgv7017n100 CNV gain 25217958
dgv7018n100 CNV gain+loss 25217958
dgv7019n100 CNV gain 25217958
dgv7020n100 CNV loss 25217958
dgv7021n100 CNV loss 25217958
dgv7025n100 CNV gain 25217958
dgv7026n100 CNV gain+loss 25217958
esv1009029 CNV gain 20482838
esv22986 CNV gain+loss 19812545
esv2736614 CNV deletion 23290073
esv2759593 CNV gain+loss 17122850
esv3343116 CNV duplication 20981092
esv3440369 CNV duplication 20981092
esv3584578 CNV gain 24956385
nsv1034132 CNV gain 25217958
nsv1077517 CNV duplication 25765185
nsv1110510 CNV duplication 24896259
nsv1139930 CNV duplication 24896259
nsv1161718 OTHER complex 26073780
nsv428195 CNV gain 18775914
nsv442420 CNV gain+loss 18776908
nsv516685 CNV gain+loss 19592680
nsv610297 CNV gain 21841781
nsv610309 CNV loss 21841781
nsv8288 CNV gain+loss 18304495
nsv951104 CNV deletion 24416366
nsv967564 CNV duplication 23825009

Additional Variant Information for USP17L7 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for USP17L7 Gene

Disorders for USP17L7 Gene

Additional Disease Information for USP17L7

No disorders were found for USP17L7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for USP17L7 Gene

Publications for USP17L7 Gene

  1. Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability. (PMID: 17109758) Shin JM … Baek KH (BMC genomics 2006) 2 3 4 58
  2. The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence. (PMID: 15780755) Burrows JF … Johnston JA (Genomics 2005) 2 3 4 58
  3. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C … Lander ES (Nature 2006) 3 4 58
  4. Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity. (PMID: 21239494) Ramakrishna S … Baek KH (The Journal of biological chemistry 2011) 3 58
  5. The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility. (PMID: 21448158) de la Vega M … Johnston JA (Nature communications 2011) 3 58

Products for USP17L7 Gene

Sources for USP17L7 Gene

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