Free for academic non-profit institutions. Other users need a Commercial license
USP17L30 (Ubiquitin Specific Peptidase 17 Like Family Member 30) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Deubiquitination. Gene Ontology (GO) annotations related to this gene include cysteine-type peptidase activity and thiol-dependent ubiquitinyl hydrolase activity. An important paralog of this gene is USP17L25.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH04J009380 | Promoter | 0.8 | CraniofacialAtlas | 0.4 | +17.8 | 17846 | 0.6 | REST CTCF NRF1 ZBTB2 ZNF423 ZNF335 GABPB1 RAD21 ETV1 MEIS2 | FAM86KP ENSG00000205959 ENSG00000288075 piR-31534-507 lnc-SLC2A9-8 USP17L30 DEFB131A | |
GH04J009444 | Promoter | 0.3 | EPDnew | 0.2 | +81.3 | 81291 | 0.1 | DEFB131A lnc-DEFB131A-2 DEFB130D USP17L30 | ||
GH04J009421 | Enhancer | 0.2 | Ensembl | 0.2 | +58.9 | 58872 | 0.8 | DEFB130D lnc-DEFB131A-2 RNA5SP153 DEFB131A USP17L30 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003723 | RNA binding | IDA | -- |
GO:0004197 | cysteine-type endopeptidase activity | IBA | -- |
GO:0004843 | thiol-dependent ubiquitin-specific protease activity | IBA | -- |
GO:0005540 | hyaluronic acid binding | IDA | -- |
GO:0008233 | peptidase activity | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA | -- |
GO:0005730 | nucleolus | IEA | -- |
GO:0005783 | endoplasmic reticulum | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Deubiquitination |
.74
|
|
2 | Metabolism of proteins |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006508 | proteolysis | IEA | -- |
GO:0006511 | ubiquitin-dependent protein catabolic process | IEA | -- |
GO:0006915 | apoptotic process | IEA | -- |
GO:0016579 | protein deubiquitination | IBA | -- |
GO:0042981 | regulation of apoptotic process | IBA | -- |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
Dog (Canis familiaris) |
Mammalia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
Mouse (Mus musculus) |
Mammalia | Usp17lb 31 |
|
ManyToMany | |
Usp17lc 31 |
|
ManyToMany | |||
Usp17la 31 |
|
ManyToMany | |||
Usp17le 31 |
|
ManyToMany | |||
Usp17ld 31 |
|
ManyToMany | |||
Zebrafish (Danio rerio) |
Actinopterygii | usp42 31 |
|
OneToMany | |
Fruit Fly (Drosophila melanogaster) |
Insecta | scny 31 |
|
OneToMany | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | UBP8 31 |
|
OneToMany |
No disorders were found for USP17L30 Gene.