USP17L23 Gene (Protein Coding)

Ubiquitin Specific Peptidase 17 Like Family Member 23

GC04P009276
GIFtS:
10
See more...

Aliases for USP17L23 Gene

Aliases for USP17L23 Gene

  • Ubiquitin Specific Peptidase 17 Like Family Member 23 2 3 5
  • Putative Ubiquitin Carboxyl-Terminal Hydrolase 17-Like Protein 23 3 4
  • USP17L23 5

External Ids for USP17L23 Gene

Summaries for USP17L23 Gene

GeneCards Summary for USP17L23 Gene

USP17L23 (Ubiquitin Specific Peptidase 17 Like Family Member 23) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include thiol-dependent ubiquitinyl hydrolase activity. An important paralog of this gene is USP17L15.

Additional gene information for USP17L23 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for USP17L23 Gene

Genomics for USP17L23 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for USP17L23 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH04J009271 Promoter 0.5 Ensembl 600.7 -0.2 -163 0.8 ZNF707 NBN USP17L23 USP17L22 ENSG00000288075
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around USP17L23 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for USP17L23 Gene

Genomic Locations for USP17L23 Gene
chr4:9,272,364-9,272,914
(GRCh38/hg38)
Size:
551 bases
Orientation:
Plus strand
chr4:9,274,090-9,274,640
(GRCh37/hg19)
Size:
551 bases
Orientation:
Plus strand

Genomic View for USP17L23 Gene

Genes around USP17L23 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
USP17L23 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for USP17L23 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

No data available for RefSeq DNA sequence for USP17L23 Gene

Proteins for USP17L23 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for USP17L23 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    D6RBM5-U17LN_HUMAN
    Recommended name:
    Putative ubiquitin carboxyl-terminal hydrolase 17-like protein 23
    Protein Accession:
    D6RBM5

    Protein attributes for USP17L23 Gene

    Size:
    183 amino acids
    Molecular mass:
    20302 Da
    Quaternary structure:
    No Data Available

neXtProt entry for USP17L23 Gene

Post-translational modifications for USP17L23 Gene

No Post-translational modifications

Other Protein References for USP17L23 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for USP17L23 Gene

Domains & Families for USP17L23 Gene

Gene Families for USP17L23 Gene

Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins

Protein Domains for USP17L23 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

D6RBM5

UniProtKB/Swiss-Prot:

U17LN_HUMAN :
  • Belongs to the peptidase C19 family. USP17 subfamily.
Family:
  • Belongs to the peptidase C19 family. USP17 subfamily.
genes like me logo Genes that share domains with USP17L23: view

No data available for Suggested Antigen Peptide Sequences for USP17L23 Gene

Function for USP17L23 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Gene Ontology (GO) - Molecular Function for USP17L23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA --
genes like me logo Genes that share ontologies with USP17L23: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for USP17L23 Gene

Localization for USP17L23 Gene

Subcellular locations from UniProtKB/Swiss-Prot for USP17L23 Gene

Nucleus. Endoplasmic reticulum.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for USP17L23 gene
Compartment Confidence
nucleus 3
endoplasmic reticulum 3

Gene Ontology (GO) - Cellular Components for USP17L23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005783 endoplasmic reticulum IEA --
genes like me logo Genes that share ontologies with USP17L23: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for USP17L23 Gene

Pathways & Interactions for USP17L23 Gene

PathCards logo

SuperPathways for USP17L23 Gene

No Data Available

Interacting Proteins for USP17L23 Gene

STRING Interaction Network Preview (showing top 5 STRING interactants - click image to see top 8)
STRING Interaction Network
Selected Interacting proteins: ENSP00000424077 for USP17L23 Gene via STRING

GPS-Prot Interaction Network for USP17L23

Gene Ontology (GO) - Biological Process for USP17L23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006511 ubiquitin-dependent protein catabolic process IEA --
GO:0016579 protein deubiquitination IEA --
genes like me logo Genes that share ontologies with USP17L23: view

No data available for Pathways by source and SIGNOR curated interactions for USP17L23 Gene

Drugs & Compounds for USP17L23 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for USP17L23 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for USP17L23 Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for USP17L23 Gene

No ASD Table

Relevant External Links for USP17L23 Gene

GeneLoc Exon Structure for
USP17L23

Expression for USP17L23 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for USP17L23 Gene

mRNA expression in normal human tissues for USP17L23 Gene
mRNA expression by GTEx for USP17L23 Gene
genes like me logo Genes that share expression patterns with USP17L23: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for USP17L23 Gene

Orthologs for USP17L23 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for USP17L23 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia USP17L23 31
  • 50 (a)
 OneToOne
Dog
(Canis familiaris)
 Mammalia -- 31
  • 19 (a)
 ManyToMany
-- 31
  • 18 (a)
 ManyToMany
-- 31
  • 18 (a)
 ManyToMany
-- 31
  • 18 (a)
 ManyToMany
-- 31
  • 18 (a)
 ManyToMany
-- 31
  • 18 (a)
 ManyToMany
-- 31
  • 18 (a)
 ManyToMany
Mouse
(Mus musculus)
 Mammalia Usp17lb 31
  • 17 (a)
 ManyToMany
Usp17le 31
  • 15 (a)
 ManyToMany
Usp17la 31
  • 14 (a)
 ManyToMany
Usp17ld 31
  • 14 (a)
 ManyToMany
Usp17lc 31
  • 14 (a)
 ManyToMany
Zebrafish
(Danio rerio)
 Actinopterygii usp42 31
  • 7 (a)
 OneToMany
Fruit Fly
(Drosophila melanogaster)
 Insecta scny 31
  • 5 (a)
 OneToMany
Baker's yeast
(Saccharomyces cerevisiae)
 Saccharomycetes UBP8 31
  • 6 (a)
 OneToMany
Species where no ortholog for USP17L23 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for USP17L23 Gene

ENSEMBL:
Gene Tree for USP17L23 (if available)
TreeFam:
Gene Tree for USP17L23 (if available)

Paralogs for USP17L23 Gene

Paralogs for USP17L23 Gene

(28) SIMAP similar genes for USP17L23 Gene using alignment to 1 proteins:

  • U17LN_HUMAN
genes like me logo Genes that share paralogs with USP17L23: view

Variants for USP17L23 Gene

Additional Variant Information for USP17L23 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
USP17L23

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for USP17L23 Gene

Disorders for USP17L23 Gene

Additional Disease Information for USP17L23

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for USP17L23 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for USP17L23 Gene

Publications for USP17L23 Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 3 4
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

ExternalLinks

View latest publications for USP17L23 gene in Mastermind

Products for USP17L23 Gene

Sources for USP17L23 Gene