Aliases for UQCC3 Gene
External Ids for UQCC3 Gene
Previous HGNC Symbols for UQCC3 Gene
Complex III is a mitochondrial inner membrane protein complex that transfers electrons from ubiquinol to cytochrome c. This gene encodes a protein that functions in complex III assembly. Mutations in this gene result in Mitochondrial complex III deficiency, nuclear type 9. [provided by RefSeq, Dec 2014]
GeneCards Summary for UQCC3 Gene
UQCC3 (Ubiquinol-Cytochrome C Reductase Complex Assembly Factor 3) is a Protein Coding gene. Diseases associated with UQCC3 include Mitochondrial Complex Iii Deficiency, Nuclear Type 9 and Isolated Complex Iii Deficiency.
UniProtKB/Swiss-Prot Summary for UQCC3 Gene
Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.