Aliases for UPRT Gene
External Ids for UPRT Gene
Previous GeneCards Identifiers for UPRT Gene
This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009]
GeneCards Summary for UPRT Gene
UPRT (Uracil Phosphoribosyltransferase Homolog) is a Protein Coding gene. Diseases associated with UPRT include Kidney Leiomyosarcoma and Congenital Toxoplasmosis. Among its related pathways are Metabolism and Metabolism of nucleotides. An important paralog of this gene is UCKL1.