Aliases for UPP2 Gene
External Ids for UPP2 Gene
Previous GeneCards Identifiers for UPP2 Gene
GeneCards Summary for UPP2 Gene
UPP2 (Uridine Phosphorylase 2) is a Protein Coding gene. Among its related pathways are Metabolism of nucleotides and Fluoropyrimidine Activity. Gene Ontology (GO) annotations related to this gene include uridine phosphorylase activity. An important paralog of this gene is UPP1.
UniProtKB/Swiss-Prot Summary for UPP2 Gene
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.