Aliases for UGT2A3 Gene
External Ids for UGT2A3 Gene
Previous GeneCards Identifiers for UGT2A3 Gene
GeneCards Summary for UGT2A3 Gene
UGT2A3 (UDP Glucuronosyltransferase Family 2 Member A3) is a Protein Coding gene. Diseases associated with UGT2A3 include Crigler-Najjar Syndrome, Type I and Gilbert Syndrome. Among its related pathways are Drug metabolism - cytochrome P450 and Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and glucuronosyltransferase activity. An important paralog of this gene is UGT2A2.
UniProtKB/Swiss-Prot Summary for UGT2A3 Gene
UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity).