Aliases for UGT2A2 Gene
External Ids for UGT2A2 Gene
Previous GeneCards Identifiers for UGT2A2 Gene
GeneCards Summary for UGT2A2 Gene
UGT2A2 (UDP Glucuronosyltransferase Family 2 Member A2) is a Protein Coding gene. Diseases associated with UGT2A2 include Kernicterus. Among its related pathways are Drug metabolism - cytochrome P450 and Porphyrin and chlorophyll metabolism. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and glucuronosyltransferase activity. An important paralog of this gene is UGT2A1.
UniProtKB/Swiss-Prot Summary for UGT2A2 Gene
UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Active on odorants and seems to be involved in olfaction; it could help clear lipophilic odorant molecules from the sensory epithelium.