UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009] See more...

Aliases for UGGT1 Gene

Aliases for UGGT1 Gene

  • UDP-Glucose Glycoprotein Glucosyltransferase 1 2 3 5
  • UDP-Glucose Ceramide Glucosyltransferase-Like 1 2 3 4
  • UDP-Glucose:Glycoprotein Glucosyltransferase 1 3 4
  • UDP--Glc:Glycoprotein Glucosyltransferase 3 4
  • UGCGL1 3 4
  • HUGT1 3 4
  • UGT1 3 4
  • EC 2.4.1.- 4
  • EC 2.4.1 52
  • UGGT 4
  • UGTR 4
  • GT 4

External Ids for UGGT1 Gene

Previous HGNC Symbols for UGGT1 Gene

  • UGCGL1

Previous GeneCards Identifiers for UGGT1 Gene

  • GC02P128566
  • GC02P128848
  • GC02P121155

Summaries for UGGT1 Gene

Entrez Gene Summary for UGGT1 Gene

  • UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009]

GeneCards Summary for UGGT1 Gene

UGGT1 (UDP-Glucose Glycoprotein Glucosyltransferase 1) is a Protein Coding gene. Diseases associated with UGGT1 include Congenital Disorder Of Glycosylation, Type Ie. Among its related pathways are Metabolism of proteins and Calnexin/calreticulin cycle. Gene Ontology (GO) annotations related to this gene include unfolded protein binding and UDP-glucose:glycoprotein glucosyltransferase activity. An important paralog of this gene is UGGT2.

UniProtKB/Swiss-Prot Summary for UGGT1 Gene

  • Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.

Additional gene information for UGGT1 Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for UGGT1 Gene

Genomics for UGGT1 Gene

GeneHancer (GH) Regulatory Elements for UGGT1 Gene

Promoters and enhancers for UGGT1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around UGGT1 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for UGGT1

Genomic Locations for UGGT1 Gene

Genomic Locations for UGGT1 Gene
chr2:128,091,180-128,195,677
(GRCh38/hg38)
Size:
104,498 bases
Orientation:
Plus strand
chr2:128,848,754-128,953,251
(GRCh37/hg19)
Size:
104,498 bases
Orientation:
Plus strand

Genomic View for UGGT1 Gene

Genes around UGGT1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UGGT1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UGGT1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UGGT1 Gene

Proteins for UGGT1 Gene

  • Protein details for UGGT1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NYU2-UGGG1_HUMAN
    Recommended name:
    UDP-glucose:glycoprotein glucosyltransferase 1
    Protein Accession:
    Q9NYU2
    Secondary Accessions:
    • Q53QP2
    • Q53SL3
    • Q8IW30
    • Q9H8I4

    Protein attributes for UGGT1 Gene

    Size:
    1555 amino acids
    Molecular mass:
    177190 Da
    Cofactor:
    Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
    Quaternary structure:
    • Monomer as well as in a tight complex with SELENOF (PubMed:24415556). Interacts with METTL23 (PubMed:23349634).
    SequenceCaution:
    • Sequence=AAY14885.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAB14632.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for UGGT1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for UGGT1 Gene

Selected DME Specific Peptides for UGGT1 Gene

Q9NYU2:
  • LEYLLLEGHC
  • AKTIDLC
  • YKILFLDVLFPL
  • RFWKSGYW
  • FRKIAAGDRLRGQYQ
  • LKNYLSPTFKE
  • YHISALYVVDL
  • NLDQDLPN
  • LQDLSFQ
  • EVQGFLFGKL
  • LLRPTFPG
  • NIFSVASGHLYERFLRIMMLSVL
  • VDADQIVR
  • VDTIVMA
  • KFWFLKNYLSP
  • AEYELEYLLLEG
  • LDGAPYGYTPFCDSRREMDGYRFWK
  • WLWCETWC
  • QPPRGLQFTLGT
  • NTKTPVKFW

Post-translational modifications for UGGT1 Gene

  • Glycosylation at Asn269, Asn536, Asn1228, and Thr1241
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect
    • UGGG1_HUMAN (1871)

Domains & Families for UGGT1 Gene

Gene Families for UGGT1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for UGGT1 Gene

Blocks:
  • UDP-glucose:Glycoprotein Glucosyltransferase
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for UGGT1 Gene

GenScript: Design optimal peptide antigens:
  • UDP-glucose ceramide glucosyltransferase-like 1 (UGGG1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9NYU2

UniProtKB/Swiss-Prot:

UGGG1_HUMAN :
  • The N-terminal non-catalytic domain is assumed to mediate recognition of proteins with partial folding defects.
  • Belongs to the glycosyltransferase 8 family.
Domain:
  • The N-terminal non-catalytic domain is assumed to mediate recognition of proteins with partial folding defects.
Family:
  • Belongs to the glycosyltransferase 8 family.
genes like me logo Genes that share domains with UGGT1: view

Function for UGGT1 Gene

Molecular function for UGGT1 Gene

UniProtKB/Swiss-Prot Function:
Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + UDP-alpha-D-glucose = H(+) + N(4)-(alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc)-L-asparaginyl-[protein] + UDP; Xref=Rhea:RHEA:61304, Rhea:RHEA-COMP:14356, Rhea:RHEA-COMP:14357, ChEBI:CHEBI:15378, ChEBI:CHEBI:58223, ChEBI:CHEBI:58885, ChEBI:CHEBI:59080, ChEBI:CHEBI:139493; Evidence=. ;.
UniProtKB/Swiss-Prot EnzymeRegulation:
Catalytic activity is enhanced by complex formation with SELENOF.
UniProtKB/Swiss-Prot Induction:
By tunicamycin and A23187. Induced 3-4 fold 10 hours after treatment.

Enzyme Numbers (IUBMB) for UGGT1 Gene

Phenotypes From GWAS Catalog for UGGT1 Gene

Gene Ontology (GO) - Molecular Function for UGGT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity IDA 10694380
GO:0005515 protein binding IPI 23349634
GO:0016740 transferase activity IEA --
GO:0016757 transferase activity, transferring glycosyl groups IEA --
GO:0051082 unfolded protein binding IEA,IDA 10694380
genes like me logo Genes that share ontologies with UGGT1: view
genes like me logo Genes that share phenotypes with UGGT1: view

Animal Models for UGGT1 Gene

MGI Knock Outs for UGGT1:
  • Uggt1 Uggt1<tm1a(KOMP)Wtsi>

Animal Model Products

CRISPR Products

miRNA for UGGT1 Gene

miRTarBase miRNAs that target UGGT1

Clone Products

  • Addgene plasmids for UGGT1

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for UGGT1 Gene

Localization for UGGT1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for UGGT1 Gene

Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for UGGT1 gene
Compartment Confidence
endoplasmic reticulum 5
plasma membrane 3
lysosome 2
golgi apparatus 2
extracellular 1
cytoskeleton 1
mitochondrion 1
nucleus 1
endosome 1
cytosol 1
peroxisome 0

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for UGGT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IBA,IDA 10694380
GO:0005788 endoplasmic reticulum lumen TAS --
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment ISS --
GO:0032991 protein-containing complex IDA 23349634
GO:0044322 endoplasmic reticulum quality control compartment IEA --
genes like me logo Genes that share ontologies with UGGT1: view

Pathways & Interactions for UGGT1 Gene

genes like me logo Genes that share pathways with UGGT1: view

Pathways by source for UGGT1 Gene

1 GeneGo (Thomson Reuters) pathway for UGGT1 Gene
  • CFTR folding and maturation (norm and CF)

UniProtKB/Swiss-Prot Q9NYU2-UGGG1_HUMAN

  • Pathway: Protein modification; protein glycosylation.

Gene Ontology (GO) - Biological Process for UGGT1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006486 protein glycosylation IEA --
GO:0018279 protein N-linked glycosylation via asparagine IBA 21873635
GO:0051084 'de novo' posttranslational protein folding TAS 10694380
GO:0071712 ER-associated misfolded protein catabolic process IBA 21873635
GO:0097359 UDP-glucosylation IEA --
genes like me logo Genes that share ontologies with UGGT1: view

No data available for SIGNOR curated interactions for UGGT1 Gene

Drugs & Compounds for UGGT1 Gene

(4) Drugs for UGGT1 Gene - From: ApexBio and HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Calcium Approved Nutra 7884
Manganese Approved Nutra 51
Caspofungin Acetate Pharma 0
Micafungin sodium Pharma Inhibitor of β-(1,3)-D-glucan synthesis;fungicide 0

(3) Additional Compounds for UGGT1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs

(2) ApexBio Compounds for UGGT1 Gene

Compound Action Cas Number
Caspofungin Acetate 179463-17-3
Micafungin sodium Inhibitor of β-(1,3)-D-glucan synthesis;fungicide 208538-73-2
genes like me logo Genes that share compounds with UGGT1: view

Drug Products

Transcripts for UGGT1 Gene

mRNA/cDNA for UGGT1 Gene

2 REFSEQ mRNAs :
11 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

  • Addgene plasmids for UGGT1

Alternative Splicing Database (ASD) splice patterns (SP) for UGGT1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20 ^
SP1: - -
SP2: - - -
SP3:
SP4: - -
SP5:
SP6: - - - - - -
SP7:
SP8:
SP9:

ExUns: 21 ^ 22 ^ 23 ^ 24a · 24b ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35 ^ 36 ^ 37 ^ 38a · 38b ^ 39 ^ 40 ^ 41a · 41b · 41c · 41d ^
SP1: - -
SP2: - -
SP3: -
SP4:
SP5: -
SP6:
SP7: -
SP8:
SP9:

ExUns: 42a · 42b ^ 43a · 43b · 43c
SP1: -
SP2: -
SP3: -
SP4:
SP5:
SP6:
SP7:
SP8: -
SP9:

Relevant External Links for UGGT1 Gene

GeneLoc Exon Structure for
UGGT1

Expression for UGGT1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for UGGT1 Gene

Protein differential expression in normal tissues from HIPED for UGGT1 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (8.8) and Lymph node (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for UGGT1 Gene



Protein tissue co-expression partners for UGGT1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for UGGT1

SOURCE GeneReport for Unigene cluster for UGGT1 Gene:

Hs.743306

mRNA Expression by UniProt/SwissProt for UGGT1 Gene:

Q9NYU2-UGGG1_HUMAN
Tissue specificity: Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart.

Evidence on tissue expression from TISSUES for UGGT1 Gene

  • Liver(4.7)
  • Adrenal gland(2.6)
  • Eye(2.6)
  • Heart(2.6)
  • Blood(2.5)
  • Pancreas(2.5)
  • Nervous system(2.1)
genes like me logo Genes that share expression patterns with UGGT1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for UGGT1 Gene

Orthologs for UGGT1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for UGGT1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UGGT1 31 30
  • 99.72 (n)
OneToOne
dog
(Canis familiaris)
Mammalia UGGT1 31 30
  • 92.42 (n)
OneToOne
cow
(Bos Taurus)
Mammalia UGGT1 31 30
  • 91.23 (n)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia UGGT1 31
  • 89 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Uggt1 30
  • 87.51 (n)
oppossum
(Monodelphis domestica)
Mammalia UGGT1 31
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Uggt1 17 31 30
  • 86.72 (n)
chicken
(Gallus gallus)
Aves UGGT1 31 30
  • 78.13 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia UGGT1 31
  • 85 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia uggt1 30
  • 71.19 (n)
zebrafish
(Danio rerio)
Actinopterygii uggt1 31 30
  • 71.49 (n)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003560 30
  • 51.92 (n)
fruit fly
(Drosophila melanogaster)
Insecta Ugt 31 30
  • 50.99 (n)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea uggt-1 31 30
  • 51.57 (n)
ManyToMany
uggt-2 31
  • 37 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes KRE5 33 31
  • 21 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons EBS1 30
  • 48.23 (n)
wheat
(Triticum aestivum)
Liliopsida Ta.29390 30
rice
(Oryza sativa)
Liliopsida Os.5900 30
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6415 31
  • 48 (a)
OneToMany
bread mold
(Neurospora crassa)
Ascomycetes NCU02349 30
  • 46.18 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes gpt1 30
  • 46.02 (n)
Species where no ortholog for UGGT1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for UGGT1 Gene

ENSEMBL:
Gene Tree for UGGT1 (if available)
TreeFam:
Gene Tree for UGGT1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for UGGT1: view image

Paralogs for UGGT1 Gene

Paralogs for UGGT1 Gene

(1) SIMAP similar genes for UGGT1 Gene using alignment to 6 proteins:

  • UGGG1_HUMAN
  • E2QRN8_HUMAN
  • F8WCE6_HUMAN
  • F8WCI2_HUMAN
  • H7BZG0_HUMAN
  • L8ECI4_HUMAN
genes like me logo Genes that share paralogs with UGGT1: view

Variants for UGGT1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for UGGT1 Gene

SNP ID Clinical significance and condition Chr 02 pos Variation AA Info Type
708636 Benign: not provided 128,171,201(+) C/T INTRON_VARIANT
708664 Benign: not provided 128,176,837(+) C/T MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
709606 Benign: not provided 128,187,578(+) C/T NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
710243 Benign: not provided 128,145,957(+) C/T MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
711014 Benign: not provided 128,173,894(+) T/C NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for UGGT1 Gene

Structural Variations from Database of Genomic Variants (DGV) for UGGT1 Gene

Variant ID Type Subtype PubMed ID
dgv2028n106 CNV deletion 24896259
esv1434860 CNV deletion 17803354
esv2187638 CNV deletion 18987734
esv2459834 CNV deletion 19546169
esv2538670 CNV deletion 19546169
esv2656463 CNV deletion 23128226
esv2720736 CNV deletion 23290073
esv275386 CNV loss 21479260
esv3560108 CNV deletion 23714750
esv3560109 CNV deletion 23714750
esv3592378 CNV loss 21293372
esv3592380 CNV gain 21293372
esv3599 CNV loss 18987735
esv7010 CNV loss 19470904
esv998959 CNV deletion 20482838
nsv1005201 CNV loss 25217958
nsv1072448 CNV deletion 25765185
nsv1142971 CNV tandem duplication 24896259
nsv470484 CNV gain 18288195
nsv7326 OTHER inversion 18451855
nsv819034 CNV loss 19587683
nsv954174 CNV deletion 24416366

Variation tolerance for UGGT1 Gene

Residual Variation Intolerance Score: 1.74% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.74; 57.70% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for UGGT1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
UGGT1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UGGT1 Gene

Disorders for UGGT1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for UGGT1 Gene - From: DISEASES

Disorder Aliases PubMed IDs
congenital disorder of glycosylation, type ie
  • congenital disorder of glycosylation, type iy
- elite association - COSMIC cancer census association via MalaCards
Search UGGT1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for UGGT1

genes like me logo Genes that share disorders with UGGT1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for UGGT1 Gene

Publications for UGGT1 Gene

  1. Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity. (PMID: 10694380) Arnold SM … Kaufman RJ (Biochemistry 2000) 2 3 4 23 54
  2. Both isoforms of human UDP-glucose:glycoprotein glucosyltransferase are enzymatically active. (PMID: 24415556) Takeda Y … Ito Y (Glycobiology 2014) 3 4 54
  3. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. (PMID: 23349634) Cloutier P … Coulombe B (PLoS genetics 2013) 3 4 54
  4. The role of UDP-Glc:glycoprotein glucosyltransferase 1 in the maturation of an obligate substrate prosaposin. (PMID: 20498017) Pearse BR … Hebert DN (The Journal of cell biology 2010) 3 23 54
  5. Identification of HUGT1 as a potential BiP activator and a cellular target for improvement of recombinant protein production using a cDNA screening system. (PMID: 19466607) Ku SC … Chao SH (Molecules and cells 2009) 3 23 54

Products for UGGT1 Gene

Sources for UGGT1 Gene