Aliases for UCKL1 Gene
External Ids for UCKL1 Gene
Previous HGNC Symbols for UCKL1 Gene
Previous GeneCards Identifiers for UCKL1 Gene
The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
GeneCards Summary for UCKL1 Gene
UCKL1 (Uridine-Cytidine Kinase 1 Like 1) is a Protein Coding gene. Among its related pathways are Pyrimidine metabolism (KEGG) and Drug metabolism - cytochrome P450. Gene Ontology (GO) annotations related to this gene include kinase activity and uridine kinase activity. An important paralog of this gene is UCK2.
UniProtKB/Swiss-Prot for UCKL1 Gene
May contribute to UTP accumulation needed for blast transformation and proliferation.