Aliases for UCHL5 Gene
External Ids for UCHL5 Gene
Previous GeneCards Identifiers for UCHL5 Gene
GeneCards Summary for UCHL5 Gene
UCHL5 (Ubiquitin C-Terminal Hydrolase L5) is a Protein Coding gene. Diseases associated with UCHL5 include Myeloma, Multiple. Among its related pathways are Metabolism of proteins and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include endopeptidase inhibitor activity. An important paralog of this gene is BAP1.
UniProtKB/Swiss-Prot Summary for UCHL5 Gene
Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.