Aliases for UBXN4 Gene
External Ids for UBXN4 Gene
Previous HGNC Symbols for UBXN4 Gene
Previous GeneCards Identifiers for UBXN4 Gene
UBXD2 is an integral membrane protein of the endoplasmic reticulum (ER) that binds valosin-containing protein (VCP; MIM 601023) and promotes ER-associated protein degradation (ERAD) (Liang et al., 2006 [PubMed 16968747]).[supplied by OMIM, Mar 2008]
GeneCards Summary for UBXN4 Gene
UBXN4 (UBX Domain Protein 4) is a Protein Coding gene. Diseases associated with UBXN4 include Martsolf Syndrome. Among its related pathways are Protein processing in endoplasmic reticulum. An important paralog of this gene is TNRC6C.
UniProtKB/Swiss-Prot Summary for UBXN4 Gene
Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD (PubMed:19822669).