External Ids for UBTD1 Gene
Previous GeneCards Identifiers for UBTD1 Gene
The degradation of many proteins is carried out by the ubiquitin pathway in which proteins are targeted for degradation by covalent conjugation of the polypeptide ubiquitin. This gene encodes a protein that belongs to the ubiquitin family of proteins. The encoded protein is thought to regulate E2 ubiquitin conjugating enzymes belonging to the UBE2D family. [provided by RefSeq, Mar 2014]
GeneCards Summary for UBTD1 Gene
UBTD1 (Ubiquitin Domain Containing 1) is a Protein Coding gene. An important paralog of this gene is UBTD2.
UniProtKB/Swiss-Prot for UBTD1 Gene
May be involved in the regulation of cellular senescence through a positive feedback loop with TP53. Is a TP53 downstream target gene that increases the stability of TP53 protein by promoting the ubiquitination and degradation of MDM2.