Aliases for UBQLN4 Gene

Aliases for UBQLN4 Gene

  • Ubiquilin 4 2 3 5
  • Ataxin-1 Ubiquitin-Like-Interacting Protein A1U 3 4
  • Ataxin-1 Interacting Ubiquitin-Like Protein 3 4
  • Ataxin-1 Ubiquitin-Like Interacting Protein 2 3
  • Connexin43-Interacting Protein Of 75 KDa 3 4
  • Ubiquilin-4 3 4
  • C1orf6 3 4
  • CIP75 3 4
  • A1Up 3 4
  • UBIN 3 4
  • Chromosome 1 Open Reading Frame 6 2
  • A1U 3

External Ids for UBQLN4 Gene

Previous HGNC Symbols for UBQLN4 Gene

  • C1orf6

Previous GeneCards Identifiers for UBQLN4 Gene

  • GC00U920633
  • GC01M152819
  • GC01M154271
  • GC01M156005
  • GC01M127367

Summaries for UBQLN4 Gene

GeneCards Summary for UBQLN4 Gene

UBQLN4 (Ubiquilin 4) is a Protein Coding gene. Diseases associated with UBQLN4 include Amyotrophic Lateral Sclerosis 1 and Mumps. Among its related pathways are Protein processing in endoplasmic reticulum. Gene Ontology (GO) annotations related to this gene include identical protein binding and damaged DNA binding. An important paralog of this gene is UBQLN1.

UniProtKB/Swiss-Prot Summary for UBQLN4 Gene

  • Regulator of protein degradation that mediates the proteasomal targeting of misfolded, mislocalized or accumulated proteins (PubMed:15280365, PubMed:27113755, PubMed:29666234, PubMed:30612738). Acts by binding polyubiquitin chains of target proteins via its UBA domain and by interacting with subunits of the proteasome via its ubiquitin-like domain (PubMed:15280365, PubMed:27113755, PubMed:30612738). Key regulator of DNA repair that represses homologous recombination repair: in response to DNA damage, recruited to sites of DNA damage following phosphorylation by ATM and acts by binding and removing ubiquitinated MRE11 from damaged chromatin, leading to MRE11 degradation by the proteasome (PubMed:30612738). MRE11 degradation prevents homologous recombination repair, redirecting double-strand break repair toward non-homologous end joining (NHEJ) (PubMed:30612738). Specifically recognizes and binds mislocalized transmembrane-containing proteins and targets them to proteasomal degradation (PubMed:27113755). Collaborates with DESI1/POST in the export of ubiquitinated proteins from the nucleus to the cytoplasm (PubMed:29666234). Also plays a role in the regulation of the proteasomal degradation of non-ubiquitinated GJA1 (By similarity). Acts as an adapter protein that recruits UBQLN1 to the autophagy machinery (PubMed:23459205). Mediates the association of UBQLN1 with autophagosomes and the autophagy-related protein LC3 (MAP1LC3A/B/C) and may assist in the maturation of autophagosomes to autolysosomes by mediating autophagosome-lysosome fusion (PubMed:23459205).

Additional gene information for UBQLN4 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for UBQLN4 Gene

Genomics for UBQLN4 Gene

GeneHancer (GH) Regulatory Elements for UBQLN4 Gene

Promoters and enhancers for UBQLN4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around UBQLN4 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for UBQLN4

Top Transcription factor binding sites by QIAGEN in the UBQLN4 gene promoter:
  • AP-2gamma
  • GATA-1
  • HEN1
  • ITF-2
  • MIF-1
  • Nkx2-5
  • Pax-3
  • Pax-5
  • Sox9
  • Tal-1beta

Genomic Locations for UBQLN4 Gene

Genomic Locations for UBQLN4 Gene
chr1:156,033,135-156,053,825
(GRCh38/hg38)
Size:
20,691 bases
Orientation:
Minus strand
chr1:156,005,092-156,023,585
(GRCh37/hg19)
Size:
18,494 bases
Orientation:
Minus strand

Genomic View for UBQLN4 Gene

Genes around UBQLN4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UBQLN4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UBQLN4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBQLN4 Gene

Proteins for UBQLN4 Gene

  • Protein details for UBQLN4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NRR5-UBQL4_HUMAN
    Recommended name:
    Ubiquilin-4
    Protein Accession:
    Q9NRR5
    Secondary Accessions:
    • A6ND44
    • B2RAY7
    • Q5VYA0
    • Q5VYA1
    • Q9BR98
    • Q9UHX4

    Protein attributes for UBQLN4 Gene

    Size:
    601 amino acids
    Molecular mass:
    63853 Da
    Quaternary structure:
    • Homooligomer (PubMed:15280365, PubMed:30612738). Binds signal sequences of proteins that are targeted to the endoplasmic reticulum (By similarity). Interacts (via UBA domain) with GJA1 (not ubiquitinated) and with ubiquitin; both compete for the same binding site (By similarity). Interacts (via UBA domain) with ubiquitin and with polyubiquitin chains (By similarity). Interacts (via ubiquitin-like domain) with PSMD2 and PSMD4, regulatory subunits of the 26S proteasome (PubMed:15280365). Interacts with ATXN1/SCA1; interaction with ATXN1 inhibits polyubiquitination of UBQLN4 and interferes with PSMD4 binding (PubMed:11001934, PubMed:15280365). Interacts with HERPUD1 (PubMed:18307982). Interacts (via ubiquitin-like domain) with UBQLN1 (via UBA domain) (PubMed:23459205). Interacts with UBQLN2 (PubMed:23459205). Interacts (via STI1 1 and 2 domains) with MAP1LC3A/B/C (PubMed:23459205). Interacts with BAG6 (PubMed:27113755). Interacts with MRE11 (when ubiquitinated); interaction with ubiquitinated MRE11 leads to MRE11 removal from chromatin (PubMed:30612738). Interacts with DESI1/POST; leading to nuclear export (PubMed:29666234).
    • (Microbial infection) Interacts with Mumps virus protein SH.
    SequenceCaution:
    • Sequence=AAF19084.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305}; Sequence=AAH06410.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};

    Alternative splice isoforms for UBQLN4 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for UBQLN4 Gene

Post-translational modifications for UBQLN4 Gene

  • Phosphorylated by ATM at Ser-318 in response to DNA damage, leading to localization in the nucleus and recruitment to sites of DNA damage.
  • Ubiquitinated; this does not lead to proteasomal degradation (PubMed:15280365). May undergo both 'Lys-48'- and 'Lys-63'-linked polyubiquitination (PubMed:15280365).
  • Ubiquitination at Lys46 and Lys59
  • Modification sites at PhosphoSitePlus

Other Protein References for UBQLN4 Gene

Antibody Products

  • Boster Bio Antibodies for UBQLN4

No data available for DME Specific Peptides for UBQLN4 Gene

Domains & Families for UBQLN4 Gene

Gene Families for UBQLN4 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transporters

Protein Domains for UBQLN4 Gene

Blocks:
  • Ubiquitin domain
  • Ubiquitin-associated domain
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for UBQLN4 Gene

GenScript: Design optimal peptide antigens:
  • Ubiquilin 4, isoform CRA_a (D3DVA8_HUMAN)
  • Ataxin-1 ubiquitin-like-interacting protein A1U (UBQL4_HUMAN)
genes like me logo Genes that share domains with UBQLN4: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for UBQLN4 Gene

Function for UBQLN4 Gene

Molecular function for UBQLN4 Gene

UniProtKB/Swiss-Prot Function:
Regulator of protein degradation that mediates the proteasomal targeting of misfolded, mislocalized or accumulated proteins (PubMed:15280365, PubMed:27113755, PubMed:29666234, PubMed:30612738). Acts by binding polyubiquitin chains of target proteins via its UBA domain and by interacting with subunits of the proteasome via its ubiquitin-like domain (PubMed:15280365, PubMed:27113755, PubMed:30612738). Key regulator of DNA repair that represses homologous recombination repair: in response to DNA damage, recruited to sites of DNA damage following phosphorylation by ATM and acts by binding and removing ubiquitinated MRE11 from damaged chromatin, leading to MRE11 degradation by the proteasome (PubMed:30612738). MRE11 degradation prevents homologous recombination repair, redirecting double-strand break repair toward non-homologous end joining (NHEJ) (PubMed:30612738). Specifically recognizes and binds mislocalized transmembrane-containing proteins and targets them to proteasomal degradation (PubMed:27113755). Collaborates with DESI1/POST in the export of ubiquitinated proteins from the nucleus to the cytoplasm (PubMed:29666234). Also plays a role in the regulation of the proteasomal degradation of non-ubiquitinated GJA1 (By similarity). Acts as an adapter protein that recruits UBQLN1 to the autophagy machinery (PubMed:23459205). Mediates the association of UBQLN1 with autophagosomes and the autophagy-related protein LC3 (MAP1LC3A/B/C) and may assist in the maturation of autophagosomes to autolysosomes by mediating autophagosome-lysosome fusion (PubMed:23459205).
UniProtKB/Swiss-Prot Induction:
Up-regulated in aggressive tumors: expression is significantly increased in stage 3 and 4 neuroblastomas, compared to stage 1 disease.

Phenotypes From GWAS Catalog for UBQLN4 Gene

Gene Ontology (GO) - Molecular Function for UBQLN4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 11001934
GO:0031593 polyubiquitin modification-dependent protein binding IDA,IBA 15280365
GO:0042802 identical protein binding IPI 11001934
genes like me logo Genes that share ontologies with UBQLN4: view
genes like me logo Genes that share phenotypes with UBQLN4: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for UBQLN4 Gene

Localization for UBQLN4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for UBQLN4 Gene

Nucleus. Cytoplasm. Chromosome. Endoplasmic reticulum. Cytoplasm, perinuclear region. Cytoplasmic vesicle, autophagosome. Note=Colocalizes with the proteasome, both in nucleus and cytoplasm (PubMed:15280365). Exported from the nucleus following interaction with DESI1/POST (PubMed:29666234). In response to DNA damage and phosphorylation at Ser-318 by ATM, localizes to the nucleus and is recruited to sites of DNA damage (PubMed:30612738). {ECO:0000269 PubMed:15280365, ECO:0000269 PubMed:29666234, ECO:0000269 PubMed:30612738}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for UBQLN4 gene
Compartment Confidence
nucleus 5
cytosol 5
endoplasmic reticulum 4
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for UBQLN4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IDA 11001934
GO:0005654 nucleoplasm IDA --
GO:0005694 chromosome IEA --
GO:0005737 cytoplasm IDA,IEA 11001934
GO:0005776 autophagosome IEA,IDA 23459205
genes like me logo Genes that share ontologies with UBQLN4: view

Pathways & Interactions for UBQLN4 Gene

PathCards logo

SuperPathways for UBQLN4 Gene

genes like me logo Genes that share pathways with UBQLN4: view

Pathways by source for UBQLN4 Gene

1 KEGG pathway for UBQLN4 Gene

Gene Ontology (GO) - Biological Process for UBQLN4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006281 DNA repair IEA --
GO:0006511 ubiquitin-dependent protein catabolic process IBA 21873635
GO:0006914 autophagy IEA --
GO:0006974 cellular response to DNA damage stimulus IEA,IDA 30612738
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process IMP 15280365
genes like me logo Genes that share ontologies with UBQLN4: view

No data available for SIGNOR curated interactions for UBQLN4 Gene

Drugs & Compounds for UBQLN4 Gene

No Compound Related Data Available

Transcripts for UBQLN4 Gene

mRNA/cDNA for UBQLN4 Gene

2 REFSEQ mRNAs :
12 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for UBQLN4 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15
SP1: -
SP2:
SP3: - -
SP4: - - -
SP5: - -
SP6: -
SP7:
SP8:

Relevant External Links for UBQLN4 Gene

GeneLoc Exon Structure for
UBQLN4

Expression for UBQLN4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for UBQLN4 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for UBQLN4 Gene

This gene is overexpressed in Bone (16.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for UBQLN4 Gene



Protein tissue co-expression partners for UBQLN4 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for UBQLN4

SOURCE GeneReport for Unigene cluster for UBQLN4 Gene:

Hs.283739

mRNA Expression by UniProt/SwissProt for UBQLN4 Gene:

Q9NRR5-UBQL4_HUMAN
Tissue specificity: Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver.

Evidence on tissue expression from TISSUES for UBQLN4 Gene

  • Nervous system(4.6)
  • Intestine(4.2)
  • Liver(4.2)
  • Muscle(2)
genes like me logo Genes that share expression patterns with UBQLN4: view

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for UBQLN4 Gene

Orthologs for UBQLN4 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for UBQLN4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UBQLN4 31 30
  • 97.25 (n)
OneToOne
cow
(Bos Taurus)
Mammalia UBQLN4 31
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia UBQLN4 31 30
  • 92.68 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Ubqln4 17 31 30
  • 90.03 (n)
rat
(Rattus norvegicus)
Mammalia Ubqln4 30
  • 89.69 (n)
oppossum
(Monodelphis domestica)
Mammalia UBQLN4 31
  • 88 (a)
OneToOne
chicken
(Gallus gallus)
Aves UBQLN4 31 30
  • 78.96 (n)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ubqln4 30
  • 72.8 (n)
LOC395047 30
African clawed frog
(Xenopus laevis)
Amphibia ubin-pending-prov 30
zebrafish
(Danio rerio)
Actinopterygii ubqln4 31 30
  • 69.04 (n)
OneToOne
wufb48e11 30
fruit fly
(Drosophila melanogaster)
Insecta Ubqn 31
  • 50 (a)
ManyToMany
CG31528 31
  • 27 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea ubql-1 31
  • 37 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes DSK2 31
  • 28 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10824 31
  • 49 (a)
OneToMany
Species where no ortholog for UBQLN4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for UBQLN4 Gene

ENSEMBL:
Gene Tree for UBQLN4 (if available)
TreeFam:
Gene Tree for UBQLN4 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for UBQLN4: view image

Paralogs for UBQLN4 Gene

Paralogs for UBQLN4 Gene

(2) SIMAP similar genes for UBQLN4 Gene using alignment to 2 proteins:

  • UBQL4_HUMAN
  • D3DVA8_HUMAN

Pseudogenes.org Pseudogenes for UBQLN4 Gene

genes like me logo Genes that share paralogs with UBQLN4: view

Variants for UBQLN4 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for UBQLN4 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
674310 Benign: not provided 156,041,653(-) T/C MISSENSE_VARIANT
711055 Likely Benign: not provided 156,042,789(-) G/A SYNONYMOUS_VARIANT
781585 Benign: not provided 156,041,545(-) G/A SYNONYMOUS_VARIANT
787857 Benign: not provided 156,048,508(-) C/T MISSENSE_VARIANT
rs1465567777 Amyotrophic lateral sclerosis (ALS) [MIM:105400] p.Asp90Ala

Additional dbSNP identifiers (rs#s) for UBQLN4 Gene

Structural Variations from Database of Genomic Variants (DGV) for UBQLN4 Gene

Variant ID Type Subtype PubMed ID
nsv509513 CNV insertion 20534489

Variation tolerance for UBQLN4 Gene

Residual Variation Intolerance Score: 50.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 12.69; 94.62% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for UBQLN4 Gene

Human Gene Mutation Database (HGMD)
UBQLN4
SNPedia medical, phenotypic, and genealogical associations of SNPs for
UBQLN4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UBQLN4 Gene

Disorders for UBQLN4 Gene

MalaCards: The human disease database

(4) MalaCards diseases for UBQLN4 Gene - From: UniProtKB/Swiss-Prot, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
amyotrophic lateral sclerosis 1
  • als1
mumps
brown-vialetto-van laere syndrome
  • pontobulbar palsy with deafness
spinocerebellar ataxia 1
  • sca1
- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

UBQL4_HUMAN
  • Amyotrophic lateral sclerosis (ALS) [MIM:105400]: A neurodegenerative disorder affecting upper motor neurons in the brain and lower motor neurons in the brain stem and spinal cord, resulting in fatal paralysis. Sensory abnormalities are absent. The pathologic hallmarks of the disease include pallor of the corticospinal tract due to loss of motor neurons, presence of ubiquitin-positive inclusions within surviving motor neurons, and deposition of pathologic aggregates. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. The disease is inherited in 5-10% of the cases. {ECO:0000269 PubMed:28463112}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
  • Note=Defects in UBQLN4 are the cause of the UBQLN4 deficiency syndrome (UBDS) (PubMed:30612738). Patients display intellectual impairment, growth retardation, microcephaly, facial dysmorphism, hearing loss, ataxia and anemia (PubMed:30612738). Cells display genomic instability characterized by hypersensitivity to genotoxic agents, leading to enhanced apoptotic cell death in response to DNA damage (PubMed:30612738). {ECO:0000269 PubMed:30612738}.

Additional Disease Information for UBQLN4

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with UBQLN4: view

No data available for Genatlas for UBQLN4 Gene

Publications for UBQLN4 Gene

  1. Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein. (PMID: 11001934) Davidson JD … Orr HT (Human molecular genetics 2000) 2 3 4 23 54
  2. The effects of the polyglutamine repeat protein ataxin-1 on the UbL-UBA protein A1Up. (PMID: 15280365) Riley BE … Orr HT (The Journal of biological chemistry 2004) 3 4 23 54
  3. Identification of two paralogous regions mapping to the short and long arms of human chromosome 2 comprising LIS1 pseudogenes. (PMID: 10575211) Fogli A … Carrozzo R (Cytogenetics and cell genetics 1999) 2 3 4 54
  4. UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. (PMID: 30612738) Jachimowicz RD … Shiloh Y (Cell 2019) 3 4 54
  5. Nuclear export of ubiquitinated proteins via the UBIN-POST system. (PMID: 29666234) Hirayama S … Nagata K (Proceedings of the National Academy of Sciences of the United States of America 2018) 3 4 54

Products for UBQLN4 Gene