Aliases for UBE2Z Gene
External Ids for UBE2Z Gene
Previous GeneCards Identifiers for UBE2Z Gene
This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis. [provided by RefSeq, Feb 2012]
GeneCards Summary for UBE2Z Gene
UBE2Z (Ubiquitin Conjugating Enzyme E2 Z) is a Protein Coding gene. Diseases associated with UBE2Z include Diabetes Mellitus, Insulin-Dependent, 19. Among its related pathways are Metabolism of proteins and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include ligase activity and ubiquitin protein ligase activity. An important paralog of this gene is UBE2O.
UniProtKB/Swiss-Prot Summary for UBE2Z Gene
Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.