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Aliases for UBE2Q2L Gene

Aliases for UBE2Q2L Gene

  • Ubiquitin Conjugating Enzyme E2 Q2 Like 2 3 5
  • Ubiquitin-Conjugating Enzyme E2Q Family Member 2-Like 2

External Ids for UBE2Q2L Gene

Previous GeneCards Identifiers for UBE2Q2L Gene

  • GC15P084843

Summaries for UBE2Q2L Gene

GeneCards Summary for UBE2Q2L Gene

UBE2Q2L (Ubiquitin Conjugating Enzyme E2 Q2 Like) is a Protein Coding gene.

Additional gene information for UBE2Q2L Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UBE2Q2L Gene

Genomics for UBE2Q2L Gene

GeneHancer (GH) Regulatory Elements for UBE2Q2L Gene

Promoters and enhancers for UBE2Q2L Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I084172 Promoter 1.1 EPDnew Ensembl 550.8 +0.5 511 1.6 SNIP1 UBE2Q2L ENSG00000259694 WDR73 SCAND2P RN7SL331P LINC00933
GH15I084714 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 11.6 +543.5 543471 3.4 CLOCK ZFP64 FEZF1 DMAP1 IRF4 YY1 E2F8 ZNF143 ZNF548 SP3 SEC11A SCAND2P WDR73 NMB GOLGA6L5P ZNF592 LINC00933 UBE2Q2P1 GOLGA6L4 CSPG4P12
GH15I084816 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE dbSUPER 4.2 +648.9 648918 9.6 HDGF FOXA2 ARNT ARID4B DMAP1 YY1 SLC30A9 ZNF143 RXRA MXD4 WDR73 ZNF592 ALPK3 NMB GOLGA6L5P ENSG00000200991 SLC28A1 GOLGA6L3 SEC11A ENSG00000259683
GH15I085023 Enhancer 0.4 dbSUPER 18.1 +850.9 850881 0.5 IKZF1 ZNF214 GC15P085023 DNM1P51 ENSG00000259683 UBE2Q2L GOLGA6L3 LOC103171574 CSPG4P12 GOLGA2P7 GC15P085002 PDE8A
GH15I084832 Enhancer 1.3 Ensembl ENCODE dbSUPER 4.2 +665.5 665467 10.4 FOXA2 PKNOX1 ATF1 NEUROD1 YY1 GLIS2 FOS ATF7 RXRA REST NMB ALPK3 ZNF592 GOLGA6L5P GOLGA6L4 LINC00933 CSPG4P11 WDR73 SCAND2P ENSG00000259683
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around UBE2Q2L on UCSC Golden Path with GeneCards custom track

Genomic Locations for UBE2Q2L Gene

Genomic Locations for UBE2Q2L Gene
chr15:84,172,490-84,182,234
(GRCh38/hg38)
Size:
9,745 bases
Orientation:
Plus strand
chr15:84,841,242-84,850,986
(GRCh37/hg19)

Genomic View for UBE2Q2L Gene

Genes around UBE2Q2L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UBE2Q2L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UBE2Q2L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBE2Q2L Gene

Proteins for UBE2Q2L Gene

  • Protein details for UBE2Q2L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H0YL09-U2Q2L_HUMAN
    Recommended name:
    Putative ubiquitin-conjugating enzyme E2Q2-like protein
    Protein Accession:
    H0YL09

    Protein attributes for UBE2Q2L Gene

    Size:
    131 amino acids
    Molecular mass:
    14853 Da
    Quaternary structure:
    No Data Available

neXtProt entry for UBE2Q2L Gene

Post-translational modifications for UBE2Q2L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for UBE2Q2L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for UBE2Q2L Gene

Domains & Families for UBE2Q2L Gene

Gene Families for UBE2Q2L Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for UBE2Q2L Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

H0YL09

UniProtKB/Swiss-Prot:

U2Q2L_HUMAN :
  • Belongs to the ubiquitin-conjugating enzyme family.
Family:
  • Belongs to the ubiquitin-conjugating enzyme family.
genes like me logo Genes that share domains with UBE2Q2L: view

No data available for Suggested Antigen Peptide Sequences for UBE2Q2L Gene

Function for UBE2Q2L Gene

Phenotypes From GWAS Catalog for UBE2Q2L Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for UBE2Q2L Gene

Localization for UBE2Q2L Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for UBE2Q2L Gene

Pathways & Interactions for UBE2Q2L Gene

SuperPathways for UBE2Q2L Gene

No Data Available

Interacting Proteins for UBE2Q2L Gene

Gene Ontology (GO) - Biological Process for UBE2Q2L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for UBE2Q2L Gene

Drugs & Compounds for UBE2Q2L Gene

No Compound Related Data Available

Transcripts for UBE2Q2L Gene

mRNA/cDNA for UBE2Q2L Gene

(3) REFSEQ mRNAs :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for UBE2Q2L Gene

No ASD Table

Relevant External Links for UBE2Q2L Gene

GeneLoc Exon Structure for
UBE2Q2L
ECgene alternative splicing isoforms for
UBE2Q2L

Expression for UBE2Q2L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for UBE2Q2L Gene

mRNA differential expression in normal tissues according to GTEx for UBE2Q2L Gene

This gene is overexpressed in Testis (x6.7).

NURSA nuclear receptor signaling pathways regulating expression of UBE2Q2L Gene:

UBE2Q2L
genes like me logo Genes that share expression patterns with UBE2Q2L: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for UBE2Q2L Gene

Orthologs for UBE2Q2L Gene

Evolution for UBE2Q2L Gene

ENSEMBL:
Gene Tree for UBE2Q2L (if available)
TreeFam:
Gene Tree for UBE2Q2L (if available)

No data available for Orthologs for UBE2Q2L Gene

Paralogs for UBE2Q2L Gene

Pseudogenes.org Pseudogenes for UBE2Q2L Gene

genes like me logo Genes that share paralogs with UBE2Q2L: view

No data available for Paralogs for UBE2Q2L Gene

Variants for UBE2Q2L Gene

Sequence variations from dbSNP and Humsavar for UBE2Q2L Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1001720243 -- 84,178,151(+) A/G/T intron_variant
rs1001813662 -- 84,176,542(+) G/T intron_variant
rs1002051050 -- 84,185,391(+) C/T genic_downstream_transcript_variant, intron_variant
rs1002116264 -- 84,182,617(+) T/A downstream_transcript_variant, genic_downstream_transcript_variant, intron_variant
rs1002145954 -- 84,184,165(+) C/G genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for UBE2Q2L Gene

Variant ID Type Subtype PubMed ID
dgv2638n100 CNV gain 25217958
dgv2639n100 CNV loss 25217958
dgv2640n100 CNV gain 25217958
dgv2641n100 CNV loss 25217958
dgv2642n100 CNV gain+loss 25217958
dgv752e212 CNV loss 25503493
esv2760048 CNV gain+loss 17122850
esv29092 CNV gain+loss 19812545
esv3569809 CNV gain 25503493
nsv1038297 CNV gain+loss 25217958
nsv1070290 CNV deletion 25765185
nsv1126405 CNV deletion 24896259
nsv1141271 CNV duplication 24896259
nsv428310 CNV gain+loss 18775914
nsv518289 CNV loss 19592680
nsv827418 CNV loss 20364138
nsv833075 CNV gain 17160897
nsv833076 CNV loss 17160897
nsv9290 CNV gain+loss 18304495
nsv976960 CNV duplication 23825009
nsv977803 CNV duplication 23825009

Variation tolerance for UBE2Q2L Gene

Gene Damage Index Score: 0.38; 8.45% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for UBE2Q2L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
UBE2Q2L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UBE2Q2L Gene

Disorders for UBE2Q2L Gene

Additional Disease Information for UBE2Q2L

No disorders were found for UBE2Q2L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UBE2Q2L Gene

Publications for UBE2Q2L Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 4 58

Products for UBE2Q2L Gene

Sources for UBE2Q2L Gene

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