Aliases for UBE2Q1 Gene
External Ids for UBE2Q1 Gene
Previous HGNC Symbols for UBE2Q1 Gene
Previous GeneCards Identifiers for UBE2Q1 Gene
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart. [provided by RefSeq, Jul 2008]
GeneCards Summary for UBE2Q1 Gene
UBE2Q1 (Ubiquitin Conjugating Enzyme E2 Q1) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Protein ubiquitination. Gene Ontology (GO) annotations related to this gene include ligase activity and acid-amino acid ligase activity. An important paralog of this gene is UBE2Q2.
UniProtKB/Swiss-Prot for UBE2Q1 Gene
Catalyzes the covalent attachment of ubiquitin to other proteins (PubMed:22496338). May be involved in hormonal homeostasis in females. Involved in regulation of B4GALT1 cell surface expression, B4GALT1-mediated cell adhesion to laminin and embryoid body formation (By similarity).