Aliases for UBE2L5 Gene

Aliases for UBE2L5 Gene

  • Ubiquitin Conjugating Enzyme E2 L5 2 3 5
  • Ubiquitin-Conjugating Enzyme E2 L5 3 4
  • Ubiquitin-Protein Ligase L5 3 4
  • Ubiquitin Conjugating Enzyme E2L 5 (Pseudogene) 2
  • Ubiquitin Conjugating Enzyme E2 L5, Pseudogene 2
  • EC 2.3.2.23 4
  • UBCH7N2 3
  • UBE2L5P 3
  • UBE2L5 5

External Ids for UBE2L5 Gene

Previous HGNC Symbols for UBE2L5 Gene

  • UBE2L5P

Summaries for UBE2L5 Gene

GeneCards Summary for UBE2L5 Gene

UBE2L5 (Ubiquitin Conjugating Enzyme E2 L5) is a Protein Coding gene. An important paralog of this gene is UBE2L3.

UniProtKB/Swiss-Prot Summary for UBE2L5 Gene

Additional gene information for UBE2L5 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for UBE2L5 Gene

Genomics for UBE2L5 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for UBE2L5 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13J030420 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 -0.5 -493 2.8 CREB1 PRDM10 RFX1 IKZF1 LARP7 PATZ1 IKZF2 POLR2A SP1 ZNF501 LINC01058 UBE2L5 lnc-UBE2L5-1 KATNAL1
GH13J030615 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 10.7 +195.5 195472 5.7 SP1 HNRNPL CREB1 GATAD2A TEAD4 PRDM10 REST ZNF629 TFE3 SIX5 USPL1 HMGB1 LINC01058 RBM22P2 UBE2L5 MFAP1P1 lnc-USPL1-3 HSALNG0096128 ALOX5AP
GH13J030351 Enhancer 0.5 dbSUPER 10.8 -69.5 -69472 2.7 ATF7 CEBPB CEBPG FOXA1 ATF4 ATF3 ZNF624 ATF2 UBE2L5 KATNAL1 ENSG00000279149 LINC00426 lnc-UBE2L5-2
GH13J030430 Promoter/Enhancer 1.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.4 +8.0 8013 3.8 ZNF629 JUND STAT3 PRDM1 IKZF2 PKNOX1 EED ARID3A DPF2 RELB KATNAL1 LINC01058 USPL1 UBE2L5 lnc-HMGB1-2 HMGB1
GH13J030407 Promoter/Enhancer 1.6 ENCODE CraniofacialAtlas dbSUPER 0.4 -13.2 -13229 2.8 GATAD2A CTCF TFE3 ZNF692 PRDM1 RBFOX2 RXRB RAD21 IRF2 SP1 lnc-UBE2L5-1 LINC01058 UBE2L5 KATNAL1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around UBE2L5 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for UBE2L5

Genomic Locations for UBE2L5 Gene

Genomic Locations for UBE2L5 Gene
chr13:30,422,488-30,429,758
(GRCh38/hg38)
Size:
7,271 bases
Orientation:
Plus strand
chr13:31,002,084-31,002,656
(GRCh37/hg19)
Size:
573 bases
Orientation:
Plus strand

Genomic View for UBE2L5 Gene

Genes around UBE2L5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UBE2L5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UBE2L5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBE2L5 Gene

Proteins for UBE2L5 Gene

  • Protein details for UBE2L5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0A1B0GUS4-UB2L5_HUMAN
    Recommended name:
    Ubiquitin-conjugating enzyme E2 L5
    Protein Accession:
    A0A1B0GUS4

    Protein attributes for UBE2L5 Gene

    Size:
    154 amino acids
    Molecular mass:
    17875 Da
    Quaternary structure:
    No Data Available

neXtProt entry for UBE2L5 Gene

Post-translational modifications for UBE2L5 Gene

Other Protein References for UBE2L5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for UBE2L5 Gene

Domains & Families for UBE2L5 Gene

Gene Families for UBE2L5 Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins

Protein Domains for UBE2L5 Gene

Graphical View of Domain Structure for InterPro Entry

A0A1B0GUS4

UniProtKB/Swiss-Prot:

UB2L5_HUMAN :
  • Belongs to the ubiquitin-conjugating enzyme family.
Family:
  • Belongs to the ubiquitin-conjugating enzyme family.
genes like me logo Genes that share domains with UBE2L5: view

No data available for Suggested Antigen Peptide Sequences for UBE2L5 Gene

Function for UBE2L5 Gene

Molecular function for UBE2L5 Gene

UniProtKB/Swiss-Prot Function:
Catalyzes the covalent attachment of ubiquitin to other proteins.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.; EC=2.3.2.23; Evidence={ECO:0000255|PROSITE-ProRule:PRU00388, ECO:0000255|PROSITE-ProRule:PRU10133};.

Enzyme Numbers (IUBMB) for UBE2L5 Gene

Phenotypes From GWAS Catalog for UBE2L5 Gene

Gene Ontology (GO) - Molecular Function for UBE2L5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0005524 ATP binding IEA --
GO:0016740 transferase activity IEA --
GO:0016874 ligase activity IEA --
GO:0031625 ubiquitin protein ligase binding IBA 21873635
genes like me logo Genes that share ontologies with UBE2L5: view

No data available for Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for UBE2L5 Gene

Localization for UBE2L5 Gene

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (1)
  • Nucleoplasm (1)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for UBE2L5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000151 ubiquitin ligase complex IBA 21873635
GO:0005634 nucleus IBA 21873635
genes like me logo Genes that share ontologies with UBE2L5: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for UBE2L5 Gene

Pathways & Interactions for UBE2L5 Gene

PathCards logo

SuperPathways for UBE2L5 Gene

No Data Available

UniProtKB/Swiss-Prot A0A1B0GUS4-UB2L5_HUMAN

  • Pathway: Protein modification; protein ubiquitination.

Interacting Proteins for UBE2L5 Gene

Gene Ontology (GO) - Biological Process for UBE2L5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000209 protein polyubiquitination IBA 21873635
GO:0006511 ubiquitin-dependent protein catabolic process IBA 21873635
GO:0016567 protein ubiquitination IEA --
GO:0070979 protein K11-linked ubiquitination IBA 21873635
genes like me logo Genes that share ontologies with UBE2L5: view

No data available for Pathways by source and SIGNOR curated interactions for UBE2L5 Gene

Drugs & Compounds for UBE2L5 Gene

No Compound Related Data Available

Transcripts for UBE2L5 Gene

mRNA/cDNA for UBE2L5 Gene

1 REFSEQ mRNAs :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for UBE2L5 Gene

No ASD Table

Relevant External Links for UBE2L5 Gene

GeneLoc Exon Structure for
UBE2L5

Expression for UBE2L5 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for UBE2L5 Gene

Orthologs for UBE2L5 Gene

Evolution for UBE2L5 Gene

ENSEMBL:
Gene Tree for UBE2L5 (if available)
TreeFam:
Gene Tree for UBE2L5 (if available)

No data available for Orthologs for UBE2L5 Gene

Paralogs for UBE2L5 Gene

genes like me logo Genes that share paralogs with UBE2L5: view

Variants for UBE2L5 Gene

Additional dbSNP identifiers (rs#s) for UBE2L5 Gene

Additional Variant Information for UBE2L5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
UBE2L5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for UBE2L5 Gene

Disorders for UBE2L5 Gene

No disorders were found for UBE2L5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UBE2L5 Gene

Publications for UBE2L5 Gene

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  2. What was the set of ubiquitin and ubiquitin-like conjugating enzymes in the eukaryote common ancestor? (PMID: 19452197) Michelle C … Andres CR (Journal of molecular evolution 2009) 23
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4
  4. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A … Ross MT (Nature 2004) 4

Products for UBE2L5 Gene

Sources for UBE2L5 Gene