Aliases for UBE2E2 Gene
External Ids for UBE2E2 Gene
Previous GeneCards Identifiers for UBE2E2 Gene
GeneCards Summary for UBE2E2 Gene
UBE2E2 (Ubiquitin Conjugating Enzyme E2 E2) is a Protein Coding gene. Diseases associated with UBE2E2 include Parkinson Disease, Late-Onset. Among its related pathways are Class I MHC mediated antigen processing and presentation and Innate Immune System. Gene Ontology (GO) annotations related to this gene include ligase activity and acid-amino acid ligase activity. An important paralog of this gene is UBE2E3.
UniProtKB/Swiss-Prot Summary for UBE2E2 Gene
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Catalyzes the ISGylation of influenza A virus NS1 protein.