Aliases for UBAP1L Gene

Aliases for UBAP1L Gene

  • Ubiquitin Associated Protein 1 Like 2 3 5
  • Ubiquitin-Associated Protein 1-Like 3 4
  • UBAP-1L 3 4

External Ids for UBAP1L Gene

Previous GeneCards Identifiers for UBAP1L Gene

  • GC15M065387

Summaries for UBAP1L Gene

GeneCards Summary for UBAP1L Gene

UBAP1L (Ubiquitin Associated Protein 1 Like) is a Protein Coding gene. An important paralog of this gene is UBAP1.

Additional gene information for UBAP1L Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for UBAP1L Gene

Genomics for UBAP1L Gene

GeneHancer (GH) Regulatory Elements for UBAP1L Gene

Promoters and enhancers for UBAP1L Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J065115 Promoter 0.5 EPDnew 500.7 0.0 -23 0.1 ZSCAN5C ZNF664 UBAP1L RBPMS2 lnc-UBAP1L-2
GH15J065868 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas 14.6 -755.3 -755309 3.8 ZBTB40 ZNF217 CTCF ZSCAN5C NRF1 TCF12 POLR2G SP1 NCOR1 GTF2E2 TRQ-CTG1-4 piR-36378-002 RAB11A PDCD7 ENSG00000260773 SLC24A1 PARP16 MTFMT UBAP1L ENSG00000259924
GH15J065082 Enhancer 1.7 VISTA FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 20.2 +29.3 29277 9.8 CTCF NRF1 USF1 ZIC2 SAP30 REST RAD21 TBX3 SMC3 HDAC2 UBAP1L SPG21 MIR1272 RASL12 ENSG00000278737 lnc-UBAP1L-1
GH15J065064 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 19.2 +46.2 46182 7.2 BCLAF1 FOS ZBTB5 EZH2 NR2F2 PHF8 FOSL1 ZFHX2 PKNOX1 NR2F1 RASL12 UBAP1L SPG21 SLC51B RBPMS2 piR-31470-194 piR-32214-224
GH15J064386 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 12.2 +727.0 726996 2.8 RXRA EP300 FOXK2 HNRNPK ZBTB40 ZNF217 CTCF ZSCAN5C SIN3A NRF1 TRIP4 PCLAF PARP16 ZNF609 UBAP1L CSNK1G1 SNX1 ENSG00000265967 PPIB CILP
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around UBAP1L on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for UBAP1L

Genomic Locations for UBAP1L Gene

Genomic Locations for UBAP1L Gene
chr15:65,092,760-65,115,197
(GRCh38/hg38)
Size:
22,438 bases
Orientation:
Minus strand
chr15:65,385,338-65,407,535
(GRCh37/hg19)
Size:
22,198 bases
Orientation:
Minus strand

Genomic View for UBAP1L Gene

Genes around UBAP1L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UBAP1L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UBAP1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBAP1L Gene

Proteins for UBAP1L Gene

  • Protein details for UBAP1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    F5GYI3-UBA1L_HUMAN
    Recommended name:
    Ubiquitin-associated protein 1-like
    Protein Accession:
    F5GYI3

    Protein attributes for UBAP1L Gene

    Size:
    381 amino acids
    Molecular mass:
    40592 Da
    Quaternary structure:
    No Data Available

neXtProt entry for UBAP1L Gene

Post-translational modifications for UBAP1L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for UBAP1L Gene

No data available for DME Specific Peptides for UBAP1L Gene

Domains & Families for UBAP1L Gene

Gene Families for UBAP1L Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for UBAP1L Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with UBAP1L: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for UBAP1L Gene

Function for UBAP1L Gene

Gene Ontology (GO) - Molecular Function for UBAP1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043130 ubiquitin binding IBA 21873635
genes like me logo Genes that share ontologies with UBAP1L: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for UBAP1L Gene

Localization for UBAP1L Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for UBAP1L gene
Compartment Confidence
endosome 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear bodies (1)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for UBAP1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000813 ESCRT I complex IBA 21873635
genes like me logo Genes that share ontologies with UBAP1L: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for UBAP1L Gene

Pathways & Interactions for UBAP1L Gene

PathCards logo

SuperPathways for UBAP1L Gene

No Data Available

Interacting Proteins for UBAP1L Gene

;

Gene Ontology (GO) - Biological Process for UBAP1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IBA 21873635
genes like me logo Genes that share ontologies with UBAP1L: view

No data available for Pathways by source and SIGNOR curated interactions for UBAP1L Gene

Drugs & Compounds for UBAP1L Gene

No Compound Related Data Available

Transcripts for UBAP1L Gene

mRNA/cDNA for UBAP1L Gene

1 REFSEQ mRNAs :
6 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for UBAP1L Gene

No ASD Table

Relevant External Links for UBAP1L Gene

GeneLoc Exon Structure for
UBAP1L

Expression for UBAP1L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for UBAP1L Gene

mRNA differential expression in normal tissues according to GTEx for UBAP1L Gene

This gene is overexpressed in Brain - Cerebellum (x5.0) and Brain - Cerebellar Hemisphere (x4.7).

Protein differential expression in normal tissues from HIPED for UBAP1L Gene

This gene is overexpressed in Ovary (28.7), Adrenal (15.7), and Gallbladder (13.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for UBAP1L Gene



Protein tissue co-expression partners for UBAP1L Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for UBAP1L

SOURCE GeneReport for Unigene cluster for UBAP1L Gene:

Hs.659256
genes like me logo Genes that share expression patterns with UBAP1L: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for UBAP1L Gene

Orthologs for UBAP1L Gene

This gene was present in the common ancestor of chordates.

Orthologs for UBAP1L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UBAP1L 31 30
  • 99.13 (n)
OneToOne
dog
(Canis familiaris)
Mammalia UBAP1L 31 30
  • 83.02 (n)
OneToOne
cow
(Bos Taurus)
Mammalia UBAP1L 30
  • 79.95 (n)
rat
(Rattus norvegicus)
Mammalia Ubap1l 30
  • 78.08 (n)
mouse
(Mus musculus)
Mammalia Gm514 31 30
  • 75.57 (n)
OneToOne
Ubap1l 17
oppossum
(Monodelphis domestica)
Mammalia UBAP1L 31
  • 50 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 13 (a)
ManyToMany
chicken
(Gallus gallus)
Aves PDCD7 30
  • 60.43 (n)
UBAP1L 31
  • 44 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia UBAP1L 31
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ubap1l 30
  • 53.19 (n)
zebrafish
(Danio rerio)
Actinopterygii UBAP1L (1 of 2) 31
  • 29 (a)
OneToMany
CABZ01068819.1 31
  • 29 (a)
OneToMany
Species where no ortholog for UBAP1L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for UBAP1L Gene

ENSEMBL:
Gene Tree for UBAP1L (if available)
TreeFam:
Gene Tree for UBAP1L (if available)
Aminode:
Evolutionary constrained regions (ECRs) for UBAP1L: view image

Paralogs for UBAP1L Gene

Paralogs for UBAP1L Gene

genes like me logo Genes that share paralogs with UBAP1L: view

Variants for UBAP1L Gene

Additional dbSNP identifiers (rs#s) for UBAP1L Gene

Structural Variations from Database of Genomic Variants (DGV) for UBAP1L Gene

Variant ID Type Subtype PubMed ID
esv2763104 CNV gain 21179565
nsv1570 CNV insertion 18451855
nsv984085 CNV duplication 23825009

Variation tolerance for UBAP1L Gene

Gene Damage Index Score: 2.42; 42.77% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for UBAP1L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
UBAP1L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for UBAP1L Gene

Disorders for UBAP1L Gene

Additional Disease Information for UBAP1L

No disorders were found for UBAP1L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UBAP1L Gene

Publications for UBAP1L Gene

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 54
  2. UMA and MABP domains throw light on receptor endocytosis and selection of endosomal cargoes. (PMID: 20448139) de Souza RF … Aravind L (Bioinformatics (Oxford, England) 2010) 3 54
  3. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 4 54
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 54
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 54

Products for UBAP1L Gene

Sources for UBAP1L Gene