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Aliases for UBAP1L Gene

Aliases for UBAP1L Gene

  • Ubiquitin Associated Protein 1 Like 2 3 5
  • UBAP-1L 3 4
  • Ubiquitin-Associated Protein 1-Like 3

External Ids for UBAP1L Gene

Previous GeneCards Identifiers for UBAP1L Gene

  • GC15M065387

Summaries for UBAP1L Gene

GeneCards Summary for UBAP1L Gene

UBAP1L (Ubiquitin Associated Protein 1 Like) is a Protein Coding gene. An important paralog of this gene is UBAP1.

Additional gene information for UBAP1L Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for UBAP1L Gene

Genomics for UBAP1L Gene

GeneHancer (GH) Regulatory Elements for UBAP1L Gene

Promoters and enhancers for UBAP1L Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I065106 Promoter 0.5 EPDnew 559.4 +8.9 8863 0.1 UBAP1L ENSG00000259258 GC15M065089
GH15I065066 Promoter/Enhancer 2 EPDnew Ensembl ENCODE dbSUPER 19.2 +45.6 45579 6 PKNOX1 NR2F1 ZMYM3 NR2F2 FOSL1 ZFHX2 GLIS1 ZKSCAN8 ZFP36 FOS RASL12 UBAP1L SPG21 SLC51B RBPMS2 PIR51727
GH15I065868 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE 14.6 -755.4 -755383 3.7 CLOCK ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 TRQ-CTG1-4 RAB11A PDCD7 PARP16 SLC24A1 INTS14 MTFMT UBAP1L TIPIN SNAPC5
GH15I064386 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE 12.2 +727.2 727227 2.2 MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 TRIP4 PCLAF PARP16 CSNK1G1 ZNF609 USP3 SNX1 UBAP1L ENSG00000265967 CILP
GH15I065048 Promoter/Enhancer 1.4 Ensembl ENCODE 17.4 +65.3 65311 1.9 HDAC1 PKNOX1 ATF1 RB1 NEUROD1 SIN3A BMI1 KLF5 ZBTB7B IRF4 ENSG00000277351 SPG21 UBAP1L CSNK1G1 MTFMT KBTBD13 RASL12 ENSG00000259635 ZNF609 MIR1272
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around UBAP1L on UCSC Golden Path with GeneCards custom track

Genomic Locations for UBAP1L Gene

Genomic Locations for UBAP1L Gene
chr15:65,092,760-65,115,197
(GRCh38/hg38)
Size:
22,438 bases
Orientation:
Minus strand
chr15:65,385,338-65,407,535
(GRCh37/hg19)

Genomic View for UBAP1L Gene

Genes around UBAP1L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UBAP1L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UBAP1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UBAP1L Gene

Proteins for UBAP1L Gene

  • Protein details for UBAP1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    F5GYI3-UBA1L_HUMAN
    Recommended name:
    Ubiquitin-associated protein 1-like
    Protein Accession:
    F5GYI3

    Protein attributes for UBAP1L Gene

    Size:
    381 amino acids
    Molecular mass:
    40592 Da
    Quaternary structure:
    No Data Available

neXtProt entry for UBAP1L Gene

Post-translational modifications for UBAP1L Gene

No Post-translational modifications

Other Protein References for UBAP1L Gene

No data available for DME Specific Peptides for UBAP1L Gene

Domains & Families for UBAP1L Gene

Gene Families for UBAP1L Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for UBAP1L Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with UBAP1L: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for UBAP1L Gene

Function for UBAP1L Gene

Gene Ontology (GO) - Molecular Function for UBAP1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043130 ubiquitin binding IBA --
genes like me logo Genes that share ontologies with UBAP1L: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for UBAP1L Gene

Localization for UBAP1L Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for UBAP1L gene
Compartment Confidence
endosome 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear bodies (1)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for UBAP1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000813 ESCRT I complex IBA --
genes like me logo Genes that share ontologies with UBAP1L: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for UBAP1L Gene

Pathways & Interactions for UBAP1L Gene

SuperPathways for UBAP1L Gene

No Data Available

Interacting Proteins for UBAP1L Gene

Gene Ontology (GO) - Biological Process for UBAP1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IBA --
genes like me logo Genes that share ontologies with UBAP1L: view

No data available for Pathways by source and SIGNOR curated interactions for UBAP1L Gene

Drugs & Compounds for UBAP1L Gene

No Compound Related Data Available

Transcripts for UBAP1L Gene

Unigene Clusters for UBAP1L Gene

Ubiquitin associated protein 1-like:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for UBAP1L Gene

No ASD Table

Relevant External Links for UBAP1L Gene

GeneLoc Exon Structure for
UBAP1L
ECgene alternative splicing isoforms for
UBAP1L

Expression for UBAP1L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for UBAP1L Gene

mRNA differential expression in normal tissues according to GTEx for UBAP1L Gene

This gene is overexpressed in Brain - Cerebellum (x5.0) and Brain - Cerebellar Hemisphere (x4.7).

Protein differential expression in normal tissues from HIPED for UBAP1L Gene

This gene is overexpressed in Ovary (28.7), Adrenal (15.7), and Gallbladder (13.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for UBAP1L Gene



Protein tissue co-expression partners for UBAP1L Gene

NURSA nuclear receptor signaling pathways regulating expression of UBAP1L Gene:

UBAP1L

SOURCE GeneReport for Unigene cluster for UBAP1L Gene:

Hs.659256
genes like me logo Genes that share expression patterns with UBAP1L: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for UBAP1L Gene

Orthologs for UBAP1L Gene

This gene was present in the common ancestor of chordates.

Orthologs for UBAP1L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UBAP1L 33 34
  • 99.13 (n)
dog
(Canis familiaris)
Mammalia UBAP1L 33 34
  • 83.02 (n)
cow
(Bos Taurus)
Mammalia UBAP1L 33
  • 79.95 (n)
rat
(Rattus norvegicus)
Mammalia Ubap1l 33
  • 78.08 (n)
mouse
(Mus musculus)
Mammalia Gm514 33 34
  • 75.57 (n)
Ubap1l 16
oppossum
(Monodelphis domestica)
Mammalia UBAP1L 34
  • 50 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 13 (a)
ManyToMany
chicken
(Gallus gallus)
Aves PDCD7 33
  • 60.43 (n)
UBAP1L 34
  • 44 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia UBAP1L 34
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ubap1l 33
  • 53.19 (n)
zebrafish
(Danio rerio)
Actinopterygii CABZ01068819.1 34
  • 29 (a)
OneToMany
UBAP1L (1 of 2) 34
  • 29 (a)
OneToMany
Species where no ortholog for UBAP1L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for UBAP1L Gene

ENSEMBL:
Gene Tree for UBAP1L (if available)
TreeFam:
Gene Tree for UBAP1L (if available)

Paralogs for UBAP1L Gene

Paralogs for UBAP1L Gene

genes like me logo Genes that share paralogs with UBAP1L: view

Variants for UBAP1L Gene

Sequence variations from dbSNP and Humsavar for UBAP1L Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000293240 -- 65,094,060(-) T/G 3_prime_UTR_variant, downstream_transcript_variant, genic_downstream_transcript_variant, intron_variant
rs1000983869 -- 65,092,340(-) C/G downstream_transcript_variant
rs1001155036 -- 65,102,206(-) GGGGG/GGGG coding_sequence_variant, frameshift, non_coding_transcript_variant
rs1001203459 -- 65,098,127(-) G/A 3_prime_UTR_variant, intron_variant, non_coding_transcript_variant
rs1001238209 -- 65,094,764(-) C/T 3_prime_UTR_variant, intron_variant, non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for UBAP1L Gene

Variant ID Type Subtype PubMed ID
nsv984085 CNV duplication 23825009
nsv1570 CNV insertion 18451855
esv2763104 CNV gain 21179565

Variation tolerance for UBAP1L Gene

Gene Damage Index Score: 2.42; 42.77% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for UBAP1L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
UBAP1L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UBAP1L Gene

Disorders for UBAP1L Gene

Additional Disease Information for UBAP1L

No disorders were found for UBAP1L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UBAP1L Gene

Publications for UBAP1L Gene

  1. UMA and MABP domains throw light on receptor endocytosis and selection of endosomal cargoes. (PMID: 20448139) de Souza RF … Aravind L (Bioinformatics (Oxford, England) 2010) 3 58
  2. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 4 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for UBAP1L Gene

Sources for UBAP1L Gene

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