Aliases for UAP1 Gene

Aliases for UAP1 Gene

  • UDP-N-Acetylglucosamine Pyrophosphorylase 1 2 3 5
  • UDP-N-Acetylhexosamine Pyrophosphorylase 1 2 3
  • UDP-N-Acetylglucosamine Diphosphorylase 1 2 3
  • UDP-N-Acetylhexosamine Pyrophosphorylase 3 4
  • Antigen X 3 4
  • SPAG2 3 4
  • AGX 3 4
  • Testis Tissue Sperm-Binding Protein Li 37a 3
  • Sperm Associated Antigen 2 3
  • Sperm-Associated Antigen 2 4
  • EC 2.7.7.23 52
  • EC 2.7.7.27 52
  • EC 2.7.7 52
  • AGX1 3
  • AGX2 3

External Ids for UAP1 Gene

Previous HGNC Symbols for UAP1 Gene

  • SPAG2

Previous GeneCards Identifiers for UAP1 Gene

  • GC01P160166
  • GC01P158182
  • GC01P159227
  • GC01P159718
  • GC01P159262
  • GC01P160797
  • GC01P162531
  • GC01P133776

Summaries for UAP1 Gene

GeneCards Summary for UAP1 Gene

UAP1 (UDP-N-Acetylglucosamine Pyrophosphorylase 1) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Amino sugar and nucleotide sugar metabolism. Gene Ontology (GO) annotations related to this gene include identical protein binding and uridylyltransferase activity. An important paralog of this gene is UAP1L1.

UniProtKB/Swiss-Prot Summary for UAP1 Gene

  • Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.

Gene Wiki entry for UAP1 Gene

Additional gene information for UAP1 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for UAP1 Gene

Genomics for UAP1 Gene

GeneHancer (GH) Regulatory Elements for UAP1 Gene

Promoters and enhancers for UAP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J162560 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 500.7 +1.0 1029 4.9 FOXK2 HNRNPK EP300 SIN3A TCF12 NRF1 POLR2G SP1 NCOR1 GTF2E2 ENSG00000259788 LOC102724358 UAP1 DUSP12 DDR2 UHMK1 OLFML2B RF00017-375
GH01J162497 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 11.6 -62.8 -62800 3.4 ZBTB40 ZNF217 TCF12 POLR2G GTF2E2 PHF8 ZFX REST POLR2A ZBTB11 UHMK1 LOC105371497 ATF6 UAP1 DUSP12 HSPA7 lnc-UAP1-4
GH01J163320 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas 9.9 +760.7 760695 3.6 RXRA EP300 FOXK2 ZBTB40 ZNF217 ZSCAN5C SIN3A NRF1 ZNF300 TCF12 NUF2 ENSG00000232995 RGS5 ENSG00000272574 RGS4 UAP1 DDR2 LOC101928404 NONHSAG003309.2
GH01J161765 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 9.9 -795.4 -795405 4.2 ZBTB40 ZNF217 EP300 ZSCAN5C MYC TCF12 POLR2G SP1 NCOR1 BCLAF1 ATF6 ENSG00000226889 LOC102724329 DUSP12 PPOX USP21 DEDD UAP1 TSTD1 FCRLB
GH01J162529 Enhancer 0.7 Ensembl ENCODE 13 -30.8 -30805 1.8 CEBPG BATF POU2F2 PKNOX1 ATF4 TBX21 SPI1 POLR2A NFIC IKZF2 HSALNG0008004 UHMK1 UAP1 lnc-UAP1-4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around UAP1 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for UAP1

Top Transcription factor binding sites by QIAGEN in the UAP1 gene promoter:
  • AML1a
  • ATF6
  • Hlf
  • Pax-4a
  • POU2F1
  • POU2F1a
  • POU2F1b
  • POU2F1c
  • POU6F1 (c2)
  • Sp1

Genomic Locations for UAP1 Gene

Genomic Locations for UAP1 Gene
chr1:162,561,506-162,599,843
(GRCh38/hg38)
Size:
38,338 bases
Orientation:
Plus strand
chr1:162,531,296-162,569,633
(GRCh37/hg19)
Size:
38,338 bases
Orientation:
Plus strand

Genomic View for UAP1 Gene

Genes around UAP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
UAP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for UAP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for UAP1 Gene

Proteins for UAP1 Gene

  • Protein details for UAP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q16222-UAP1_HUMAN
    Recommended name:
    UDP-N-acetylhexosamine pyrophosphorylase
    Protein Accession:
    Q16222
    Secondary Accessions:
    • B2R6R8
    • Q5VTA9
    • Q5VTB0
    • Q5VTB1
    • Q96GM2

    Protein attributes for UAP1 Gene

    Size:
    522 amino acids
    Molecular mass:
    58769 Da
    Quaternary structure:
    • Monomer and homodimer. Isoform AGX1 is a homodimer. Isoform AGX2 is a monomer.

    Three dimensional structures from OCA and Proteopedia for UAP1 Gene

    Alternative splice isoforms for UAP1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for UAP1 Gene

Selected DME Specific Peptides for UAP1 Gene

Q16222:
  • EFSPLKN
  • YCVDNIL
  • ADCGAKVV
  • VAVLLLAGGQ
  • VVEYSEIS
  • LAGGQGTRLGV
  • GADCGAKVVEK

Post-translational modifications for UAP1 Gene

  • Ubiquitination at Lys12 and Lys63
  • Modification sites at PhosphoSitePlus

Domains & Families for UAP1 Gene

Gene Families for UAP1 Gene

Human Protein Atlas (HPA):
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for UAP1 Gene

Blocks:
  • UTP--glucose-1-phosphate uridylyltransferase
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for UAP1 Gene

GenScript: Design optimal peptide antigens:
  • Sperm-associated antigen 2 (UAP1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q16222

UniProtKB/Swiss-Prot:

UAP1_HUMAN :
  • Belongs to the UDPGP type 1 family.
Family:
  • Belongs to the UDPGP type 1 family.
genes like me logo Genes that share domains with UAP1: view

Function for UAP1 Gene

Molecular function for UAP1 Gene

UniProtKB/Swiss-Prot Function:
Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-galactosamine; Xref=Rhea:RHEA:34363, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:61970, ChEBI:CHEBI:67138; EC=2.7.7.83; Evidence=. ;.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine; Xref=Rhea:RHEA:13509, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:57705, ChEBI:CHEBI:57776; EC=2.7.7.23; Evidence=. ;.

Enzyme Numbers (IUBMB) for UAP1 Gene

Phenotypes From GWAS Catalog for UAP1 Gene

Gene Ontology (GO) - Molecular Function for UAP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity IBA 21873635
GO:0016740 transferase activity IEA --
GO:0016779 nucleotidyltransferase activity IEA --
GO:0030246 carbohydrate binding IEA --
GO:0042802 identical protein binding IPI 25416956
genes like me logo Genes that share ontologies with UAP1: view
genes like me logo Genes that share phenotypes with UAP1: view

Animal Model Products

CRISPR Products

miRNA for UAP1 Gene

miRTarBase miRNAs that target UAP1

Clone Products

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for UAP1 Gene

Localization for UAP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for UAP1 Gene

Cytoplasm. Note=In spermatozoa, localized to the principal piece of the tail, the neck region of the head and to a lesser extent, the midpiece of the tail.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for UAP1 gene
Compartment Confidence
nucleus 5
cytosol 5
plasma membrane 4
extracellular 1
cytoskeleton 1
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Nucleoplasm (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for UAP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol TAS,IEA --
GO:0005886 plasma membrane IDA --
genes like me logo Genes that share ontologies with UAP1: view

Pathways & Interactions for UAP1 Gene

genes like me logo Genes that share pathways with UAP1: view

UniProtKB/Swiss-Prot Q16222-UAP1_HUMAN

  • Pathway: Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.

Gene Ontology (GO) - Biological Process for UAP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006047 UDP-N-acetylglucosamine metabolic process IEA --
GO:0006048 UDP-N-acetylglucosamine biosynthetic process IBA,TAS --
genes like me logo Genes that share ontologies with UAP1: view

No data available for SIGNOR curated interactions for UAP1 Gene

Drugs & Compounds for UAP1 Gene

(6) Drugs for UAP1 Gene - From: DrugBank, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phosphoric acid Approved Pharma 0
Uridine-Diphosphate-N-Acetylgalactosamine Experimental Pharma Target 0
Uridine-Diphosphate-N-Acetylglucosamine Experimental Pharma Target 0
Uridine triphosphate Experimental, Investigational Pharma 0

(7) Additional Compounds for UAP1 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Glucosamine-1P
  • alpha-D-Glucosamine 1-phosphate
  • alpha-D-Glucosamine 1P
  • alpha-delta-Glucosamine 1-phosphate
  • alpha-delta-Glucosamine 1P
N-acetyl-alpha-D-galactosamine 1-phosphate
  • 2-acetamido-2-Deoxy-1-O-phosphono-alpha-D-galactopyranose
  • 2-acetamido-2-Deoxy-1-O-phosphono-a-D-galactopyranose
  • 2-acetamido-2-Deoxy-1-O-phosphono-α-D-galactopyranose
  • N-Acetyl-a-D-galactosamine 1-phosphate
  • N-Acetyl-a-D-galactosamine 1-phosphoric acid
N-Acetyl-glucosamine 1-phosphate
  • 2-(acetylamino)-2-Deoxy-D-glucopyranose 1-(dihydrogen phosphate)
  • 2-acetamido-2-Deoxy-1-O-phosphono-D-glucopyranose
  • N-Acetyl-D-glucosamine 1-phosphate
  • N-Acetylglucosamine-1-phosphate
  • 2-(acetylamino)-2-Deoxy-D-glucopyranose 1-(dihydrogen phosphoric acid)
6866-69-9
pyrophosphate
  • [(ho)2P(O)OP(O)(OH)2]
  • Acide diphosphorique
  • Diphosphorsaeure
  • H4P2O7
  • PYROphosphATE
14000-31-8
UDP-N-acetyl-alpha-D-galactosamine
  • (2R,3R,4R,5R,6R)-3-(acetylamino)-4,5-Dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name)
  • URIDINE-diphosphATE-N-acetylgalactosamine
  • (2R,3R,4R,5R,6R)-3-(acetylamino)-4,5-Dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphoric acid (non-preferred name)
  • UDP-N-Acetyl-a-D-galactosamine
  • UDP-N-Acetyl-α-D-galactosamine
genes like me logo Genes that share compounds with UAP1: view

Transcripts for UAP1 Gene

mRNA/cDNA for UAP1 Gene

6 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for UAP1 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b · 13c
SP1: - - - - - -
SP2: - -
SP3: - -
SP4: -
SP5: -
SP6: -
SP7: -
SP8:
SP9:

Relevant External Links for UAP1 Gene

GeneLoc Exon Structure for
UAP1

Expression for UAP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for UAP1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for UAP1 Gene

This gene is overexpressed in Nasal epithelium (10.2), Salivary gland (9.6), Oral epithelium (8.3), Skin (7.9), and Bone marrow stromal cell (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for UAP1 Gene



Protein tissue co-expression partners for UAP1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for UAP1

SOURCE GeneReport for Unigene cluster for UAP1 Gene:

Hs.492859

mRNA Expression by UniProt/SwissProt for UAP1 Gene:

Q16222-UAP1_HUMAN
Tissue specificity: Widely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver.

Evidence on tissue expression from TISSUES for UAP1 Gene

  • Liver(4.4)
  • Muscle(4.2)
  • Nervous system(2.4)
  • Stomach(2)
genes like me logo Genes that share expression patterns with UAP1: view

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for UAP1 Gene

Orthologs for UAP1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for UAP1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia UAP1 31 30
  • 99.67 (n)
OneToOne
cow
(Bos Taurus)
Mammalia UAP1 31 30
  • 93.6 (n)
OneToOne
dog
(Canis familiaris)
Mammalia UAP1 31 30
  • 92.54 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Uap1 17 31 30
  • 88.65 (n)
oppossum
(Monodelphis domestica)
Mammalia UAP1 31
  • 88 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Uap1 30
  • 86.93 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia UAP1 31
  • 67 (a)
OneToOne
chicken
(Gallus gallus)
Aves UAP1 31 30
  • 70.45 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia UAP1 31
  • 77 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia uap1 30
  • 69.64 (n)
Str.2734 30
African clawed frog
(Xenopus laevis)
Amphibia Xl.5556 30
zebrafish
(Danio rerio)
Actinopterygii uap1 31 30
  • 70.7 (n)
OneToOne
Dr.3773 30
fruit fly
(Drosophila melanogaster)
Insecta mmy 31 30
  • 56.41 (n)
OneToMany
BcDNA:LD24639 32
  • 51 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007889 30
  • 54.66 (n)
worm
(Caenorhabditis elegans)
Secernentea K06B9.2 32
  • 43 (a)
C36A4.4 31 32
  • 35 (a)
OneToMany
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E01673g 30
  • 50.52 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes QRI1 33 31 30
  • 50.18 (n)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFL192C 30
  • 49.02 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons GlcNA.1UT2 30
  • 52.55 (n)
rice
(Oryza sativa)
Liliopsida Os04g0613700 30
  • 53.12 (n)
bread mold
(Neurospora crassa)
Ascomycetes NCU02109 30
  • 52.21 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes uap1 30
  • 47.56 (n)
sea squirt
(Ciona savignyi)
Ascidiacea Cin.5408 30
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.5408 30
Species where no ortholog for UAP1 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for UAP1 Gene

ENSEMBL:
Gene Tree for UAP1 (if available)
TreeFam:
Gene Tree for UAP1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for UAP1: view image

Paralogs for UAP1 Gene

Paralogs for UAP1 Gene

(1) SIMAP similar genes for UAP1 Gene using alignment to 1 proteins:

  • UAP1_HUMAN

Pseudogenes.org Pseudogenes for UAP1 Gene

genes like me logo Genes that share paralogs with UAP1: view

Variants for UAP1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for UAP1 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
736036 Likely Benign: not provided 162,590,335(+) A/G SYNONYMOUS_VARIANT
767720 Benign: not provided 162,587,615(+) G/A SYNONYMOUS_VARIANT
769246 Benign: not provided 162,599,280(+) A/G MISSENSE_VARIANT
772818 Benign: not provided 162,576,990(+) C/T INTRON_VARIANT
772819 Benign: not provided 162,590,324(+) A/C MISSENSE_VARIANT

Additional dbSNP identifiers (rs#s) for UAP1 Gene

Structural Variations from Database of Genomic Variants (DGV) for UAP1 Gene

Variant ID Type Subtype PubMed ID
nsv516482 CNV gain+loss 19592680

Variation tolerance for UAP1 Gene

Residual Variation Intolerance Score: 45.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.93; 59.51% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for UAP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
UAP1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for UAP1 Gene

Disorders for UAP1 Gene

Additional Disease Information for UAP1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for UAP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for UAP1 Gene

Publications for UAP1 Gene

  1. The eukaryotic UDP-N-acetylglucosamine pyrophosphorylases. Gene cloning, protein expression, and catalytic mechanism. (PMID: 9603950) Mio T … Yamada-Okabe H (The Journal of biological chemistry 1998) 2 3 4 23 54
  2. Characterization of a human antigen with sera from infertile patients. (PMID: 8025165) Diekman AB … Goldberg E (Biology of reproduction 1994) 2 3 4 23 54
  3. Crystal structures of two human pyrophosphorylase isoforms in complexes with UDPGlc(Gal)NAc: role of the alternatively spliced insert in the enzyme oligomeric assembly and active site architecture. (PMID: 11707391) Peneff C … Bourne Y (The EMBO journal 2001) 3 4 23 54
  4. A 17-amino acid insert changes UDP-N-acetylhexosamine pyrophosphorylase specificity from UDP-GalNAc to UDP-GlcNAc. (PMID: 9765219) Wang-Gillam A … Elbein AD (The Journal of biological chemistry 1998) 3 4 23 54
  5. Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. (PMID: 19536175) Ehret GB … Chakravarti A (European journal of human genetics : EJHG 2009) 3 41 54

Products for UAP1 Gene

Sources for UAP1 Gene