Aliases for TCN2 Gene
External Ids for TCN2 Gene
Previous GeneCards Identifiers for TCN2 Gene
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
GeneCards Summary for TCN2 Gene
TCN2 (Transcobalamin 2) is a Protein Coding gene. Diseases associated with TCN2 include Transcobalamin Ii Deficiency and Vitamin B12 Deficiency. Among its related pathways are Metabolism of water-soluble vitamins and cofactors and One carbon pool by folate. Gene Ontology (GO) annotations related to this gene include cobalamin binding. An important paralog of this gene is TCN1.
UniProtKB/Swiss-Prot Summary for TCN2 Gene
Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells.