Aliases for TYSND1 Gene
External Ids for TYSND1 Gene
Previous GeneCards Identifiers for TYSND1 Gene
This gene encodes a protease that removes the N-terminal peroxisomal targeting signal (PTS2) from proteins produced in the cytosol, thereby facilitating their import into the peroxisome. The encoded protein is also capable of removing the C-terminal peroxisomal targeting signal (PTS1) from proteins in the peroxisomal matrix. The full-length protein undergoes self-cleavage to produce shorter, potentially inactive, peptides. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]
GeneCards Summary for TYSND1 Gene
TYSND1 (Trypsin Domain Containing 1) is a Protein Coding gene. Diseases associated with TYSND1 include Peroxisomal Acyl-Coa Oxidase Deficiency and Peroxisome Biogenesis Disorder 1B. Gene Ontology (GO) annotations related to this gene include identical protein binding and protease binding.
UniProtKB/Swiss-Prot Summary for TYSND1 Gene
Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.