Aliases for TYRL Gene

Aliases for TYRL Gene

  • Tyrosinase Like (Pseudogene) 2 3 5
  • Tyrosinase-Like 2
  • TYRL Protein 13
  • TYRL 5

External Ids for TYRL Gene

Previous GeneCards Identifiers for TYRL Gene

  • GC11U990136
  • GC11M050647
  • GC11M049457
  • GC11M049390
  • GC11M049382
  • GC11M049495
  • GC11M049924
  • GC11M049684
  • GC11M049709
  • GC11M055849
  • GC11M056092
  • GC11M056231
  • GC11M059744
  • GC11M050829
  • GC11M051623
  • GC11M052285
  • GC11M052945
  • GC11M053614
  • GC11M054279
  • GC11M054945
  • GC11M055652

Summaries for TYRL Gene

GeneCards Summary for TYRL Gene

TYRL (Tyrosinase Like (Pseudogene)) is a Pseudogene.

Additional gene information for TYRL Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TYRL Gene

Genomics for TYRL Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TYRL Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J049423 Enhancer 0.2 Ensembl 0.4 -8.2 -8212 0.8 FOLH1 RF00994-180 TYRL OR4C13
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TYRL on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for TYRL Gene

Genomic Locations for TYRL Gene
11,095 bases
Minus strand
11,063 bases
Minus strand

Genomic View for TYRL Gene

Genes around TYRL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TYRL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TYRL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TYRL Gene

Proteins for TYRL Gene

  • Protein details for TYRL Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    TYRL protein
    Protein Accession:

    Protein attributes for TYRL Gene

    73 amino acids
    Molecular mass:
    8416 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TYRL Gene

Post-translational modifications for TYRL Gene

No Post-translational modifications

No data available for DME Specific Peptides for TYRL Gene

Domains & Families for TYRL Gene

Protein Domains for TYRL Gene


Suggested Antigen Peptide Sequences for TYRL Gene

GenScript: Design optimal peptide antigens:
  • Tyrosinase-related gene segment, exon 5 (Q15677_HUMAN)
  • TYRL protein (Q9UMA1_HUMAN)
genes like me logo Genes that share domains with TYRL: view

No data available for Gene Families , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TYRL Gene

Function for TYRL Gene

Molecular function for TYRL Gene

GENATLAS Biochemistry:

Phenotypes From GWAS Catalog for TYRL Gene

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TYRL Gene

Localization for TYRL Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TYRL Gene

Pathways & Interactions for TYRL Gene

PathCards logo

SuperPathways for TYRL Gene

No Data Available

Gene Ontology (GO) - Biological Process for TYRL Gene


No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for TYRL Gene

Drugs & Compounds for TYRL Gene

(1) Drugs for TYRL Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(1) Additional Compounds for TYRL Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with TYRL: view

Transcripts for TYRL Gene

mRNA/cDNA for TYRL Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for TYRL Gene

No ASD Table

Relevant External Links for TYRL Gene

GeneLoc Exon Structure for

Expression for TYRL Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TYRL Gene

mRNA differential expression in normal tissues according to GTEx for TYRL Gene

This gene is overexpressed in Testis (x36.1) and Brain - Caudate (basal ganglia) (x4.6).
genes like me logo Genes that share expression patterns with TYRL: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TYRL Gene

Orthologs for TYRL Gene

Evolution for TYRL Gene

Gene Tree for TYRL (if available)
Gene Tree for TYRL (if available)

No data available for Orthologs for TYRL Gene

Paralogs for TYRL Gene

(2) SIMAP similar genes for TYRL Gene using alignment to 2 proteins:

  • Q15677_HUMAN
genes like me logo Genes that share paralogs with TYRL: view

No data available for Paralogs for TYRL Gene

Variants for TYRL Gene

Additional Variant Information for TYRL Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TYRL Gene

Disorders for TYRL Gene

Additional Disease Information for TYRL

Genetic Association Database

No disorders were found for TYRL Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TYRL Gene

Publications for TYRL Gene

  1. Evolution of the tyrosinase related gene (TYRL) in primates. (PMID: 8234203) Oetting WS … King RA (Pigment cell research 1993) 2 3 13
  2. Tyrosinase and ocular diseases: some novel thoughts on the molecular basis of oculocutaneous albinism type 1. (PMID: 17355913) Ray K … Sengupta M (Progress in retinal and eye research 2007) 2 3
  3. Organization and nucleotide sequences of the human tyrosinase gene and a truncated tyrosinase-related segment. (PMID: 1903356) Giebel LB … Spritz RA (Genomics 1991) 2 3
  4. Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer. (PMID: 30652415) Liu Y … Chen L (Cancer medicine 2019) 3
  5. Modeling tyrosinase activity. Effect of ligand topology on aromatic ring hydroxylation: an overview. (PMID: 18336914) De A … Mukherjee R (Journal of inorganic biochemistry 2008) 23

Products for TYRL Gene

Sources for TYRL Gene