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Aliases for TYMP Gene

Aliases for TYMP Gene

  • Thymidine Phosphorylase 2 3 5
  • Gliostatin 2 3 4
  • EC 2.4.2.4 4 56
  • TdRPase 3 4
  • ECGF1 3 4
  • TP 3 4
  • Endothelial Cell Growth Factor 1 (Platelet-Derived) 2
  • Platelet-Derived Endothelial Cell Growth Factor 4
  • HPD-ECGF 3
  • EC 2.4.2 56
  • PD-ECGF 4
  • MEDPS1 3
  • MTDPS1 3
  • PDECGF 3
  • MNGIE 3
  • ECGF 3

External Ids for TYMP Gene

Previous HGNC Symbols for TYMP Gene

  • MNGIE
  • ECGF1

Previous GeneCards Identifiers for TYMP Gene

  • GC22M049312
  • GC22M050964
  • GC22M033855

Summaries for TYMP Gene

Entrez Gene Summary for TYMP Gene

  • This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]

GeneCards Summary for TYMP Gene

TYMP (Thymidine Phosphorylase) is a Protein Coding gene. Diseases associated with TYMP include Mitochondrial Dna Depletion Syndrome 1 and Mitochondrial Neurogastrointestinal Encephalomyopathy. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and PAK Pathway. Gene Ontology (GO) annotations related to this gene include growth factor activity and platelet-derived growth factor receptor binding.

UniProtKB/Swiss-Prot for TYMP Gene

  • May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro.

  • Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

Gene Wiki entry for TYMP Gene

Additional gene information for TYMP Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TYMP Gene

Genomics for TYMP Gene

GeneHancer (GH) Regulatory Elements for TYMP Gene

Promoters and enhancers for TYMP Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22I050523 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 571.7 +0.4 381 12.1 HDGF PKNOX1 CLOCK FOXA2 SMAD1 MLX ARNT ARID4B SIN3A DMAP1 SCO2 TYMP ODF3B RABL2B ENSG00000272821 SYCE3 BRD1 CHKB ENSG00000272836 PLXNB2
GH22I050536 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 48.1 -13.6 -13581 13.7 HDGF FOXA2 PKNOX1 SMAD1 ARNT ARID4B SIN3A IRF4 YY1 SLC30A9 LOC105373098 TYMP ODF3B ENSG00000272821 CPT1B SCO2 CHKB SYCE3 ARSA TUBGCP6
GH22I050292 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 13.5 +229.0 228978 17.7 HDGF FOXA2 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 YY1 SLC30A9 PLXNB2 PIM3 BRD1 NCAPH2 RABL2B TYMP TUBGCP6 DENND6B LOC105373100 ODF3B
GH22I050505 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 12.2 +22.2 22232 4.2 PKNOX1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 POLR2B E2F8 LMF2 NCAPH2 SYCE3 CHKB ALG12 ENSG00000273192 TRABD PLXNB2 TYMP MIOX
GH22I050398 Enhancer 1.2 FANTOM5 Ensembl ENCODE 20.2 +130.4 130398 2.4 CTCF FOXA2 USF1 SAP130 ARID4B MAX ZIC2 RAD21 YY1 HNF4G GC22P050399 TYMP ODF3B MIOX PIM3 PLXNB2 TRABD CHKB SCO2 HDAC10
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TYMP on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TYMP gene promoter:

Genomic Locations for TYMP Gene

Genomic Locations for TYMP Gene
chr22:50,525,752-50,530,085
(GRCh38/hg38)
Size:
4,334 bases
Orientation:
Minus strand
chr22:50,964,181-50,968,514
(GRCh37/hg19)

Genomic View for TYMP Gene

Genes around TYMP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TYMP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TYMP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TYMP Gene

Proteins for TYMP Gene

  • Protein details for TYMP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P19971-TYPH_HUMAN
    Recommended name:
    Thymidine phosphorylase
    Protein Accession:
    P19971
    Secondary Accessions:
    • A8MW15
    • H9KVA0
    • Q13390
    • Q8WVB7

    Protein attributes for TYMP Gene

    Size:
    482 amino acids
    Molecular mass:
    49955 Da
    Quaternary structure:
    • Homodimer.

    Three dimensional structures from OCA and Proteopedia for TYMP Gene

    Alternative splice isoforms for TYMP Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TYMP Gene

Selected DME Specific Peptides for TYMP Gene

P19971:
  • VPMISGRGLGHTGGTLDK
  • LITASIL
  • DKHSTGG
  • SGRGLGHTGGT
  • LGHTGGTLDKLE
  • RDVTATV

Post-translational modifications for TYMP Gene

No Post-translational modifications

Antibody Products

  • R&D Systems Antibodies for TYMP (PD-ECGF/Thymidine Phosphorylase)
  • Cell Signaling Technology (CST) Antibodies for TYMP (ECGF1)

Domains & Families for TYMP Gene

Gene Families for TYMP Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Disease related genes
  • Enzymes
  • Plasma proteins
  • Potential drug targets
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for TYMP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P19971

UniProtKB/Swiss-Prot:

TYPH_HUMAN :
  • Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Family:
  • Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
genes like me logo Genes that share domains with TYMP: view

Function for TYMP Gene

Molecular function for TYMP Gene

UniProtKB/Swiss-Prot CatalyticActivity:
Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.
UniProtKB/Swiss-Prot Function:
May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro.
UniProtKB/Swiss-Prot Function:
Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

Enzyme Numbers (IUBMB) for TYMP Gene

Phenotypes From GWAS Catalog for TYMP Gene

Gene Ontology (GO) - Molecular Function for TYMP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004645 phosphorylase activity IEA,IBA --
GO:0008083 growth factor activity IEA --
GO:0009032 thymidine phosphorylase activity IMP 9924029
GO:0016154 pyrimidine-nucleoside phosphorylase activity IEA --
GO:0016740 transferase activity IEA --
genes like me logo Genes that share ontologies with TYMP: view
genes like me logo Genes that share phenotypes with TYMP: view

Human Phenotype Ontology for TYMP Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for TYMP Gene

MGI Knock Outs for TYMP:

miRNA for TYMP Gene

miRTarBase miRNAs that target TYMP

Clone Products

No data available for Transcription Factor Targets and HOMER Transcription for TYMP Gene

Localization for TYMP Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TYMP gene
Compartment Confidence
cytosol 4
mitochondrion 3
nucleus 3
extracellular 2
golgi apparatus 2
peroxisome 1
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (2)
  • Nuclear bodies (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for TYMP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol TAS,IBA --
genes like me logo Genes that share ontologies with TYMP: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for TYMP Gene

Pathways & Interactions for TYMP Gene

genes like me logo Genes that share pathways with TYMP: view

UniProtKB/Swiss-Prot P19971-TYPH_HUMAN

  • Pathway: Pyrimidine metabolism; dTMP biosynthesis via salvage pathway; dTMP from thymine: step 1/2.

Gene Ontology (GO) - Biological Process for TYMP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000002 mitochondrial genome maintenance IMP 9924029
GO:0001525 angiogenesis IEA --
GO:0006206 pyrimidine nucleobase metabolic process IEA --
GO:0006213 pyrimidine nucleoside metabolic process IEA,IMP 9924029
GO:0006935 chemotaxis IEA --
genes like me logo Genes that share ontologies with TYMP: view

No data available for SIGNOR curated interactions for TYMP Gene

Drugs & Compounds for TYMP Gene

(66) Drugs for TYMP Gene - From: DrugBank, PharmGKB, ApexBio, FDA Approved Drugs, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Capecitabine Approved, Investigational Pharma Enzyme, substrate RNA processing inhibitor and thymidylate synthase inhibitor, F-pyrimidines 1402
Fluorouracil Approved Pharma Enzyme, substrate RNA processing inhibitor and thymidylate synthase inhibitor 1970
Cidofovir Approved Pharma Enzyme, inhibitor 33
Floxuridine Approved Pharma Enzyme, substrate Antineoplastic antimetabolite, RNA and DNA synthesis inhibitor 50
Trifluridine Approved, Investigational Pharma Enzyme, substrate 35

(50) Additional Compounds for TYMP Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
5'-Deoxy-5-fluorouridine
5-Deoxyribose-1-phosphate
Deoxyribose 1-phosphate
  • 2-Deoxy-alpha-D-ribose 1-phosphate
  • 2-Deoxy-alpha-delta-ribose 1-phosphate
  • 2-Deoxy-D-erythro-pentofuranose 1-phosphate
  • 2-Deoxy-D-ribose 1-phosphate
  • 2-Deoxy-D-ribose-1-phosphate
17210-42-3

(5) ApexBio Compounds for TYMP Gene

Compound Action Cas Number
Doxifluridine 3094-09-5
INDY Dyrk1A and Dyrk1B inhibitor, selective 1169755-45-6
ProINDY 719277-30-2
Tipiracil hydrochloride Thymidine phosphorylase inhibitor 183204-72-0
Triflurdine (Viroptic) Anti-herpesvirus antiviral drug 70-00-8
genes like me logo Genes that share compounds with TYMP: view

Drug Products

Transcripts for TYMP Gene

Unigene Clusters for TYMP Gene

Thymidine phosphorylase:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TYMP Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d · 2e · 2f · 2g ^ 3a · 3b · 3c · 3d · 3e · 3f ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c · 5d ^ 6a · 6b ·
SP1: - - - - - - - - -
SP2: - - - - - - - - - - - -
SP3: - - - - - - -
SP4: - - - - - - - - - - -
SP5: - - - - - - - - - - - - - - - - - - - - -
SP6: - - - - - - - - - - - - - - -
SP7: - - - - - - -
SP8: - - - - - - - - -
SP9: - - - - - - - -
SP10: - - -
SP11: - -
SP12: - - -
SP13: - - - - -
SP14: - - - - - - - - - - - - - -
SP15: - - -
SP16: - - - -
SP17: - - - - -
SP18:
SP19: -
SP20:
SP21:

ExUns: 6c ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11
SP1: -
SP2: -
SP3: -
SP4:
SP5:
SP6:
SP7: -
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15: -
SP16:
SP17:
SP18:
SP19:
SP20:
SP21: - -

Relevant External Links for TYMP Gene

GeneLoc Exon Structure for
TYMP
ECgene alternative splicing isoforms for
TYMP

Expression for TYMP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TYMP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TYMP Gene

This gene is overexpressed in Whole Blood (x13.9).

Protein differential expression in normal tissues from HIPED for TYMP Gene

This gene is overexpressed in Spleen (7.6), Tonsil (7.2), and Lymph node (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for TYMP Gene



Protein tissue co-expression partners for TYMP Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TYMP Gene:

TYMP

SOURCE GeneReport for Unigene cluster for TYMP Gene:

Hs.180903

Evidence on tissue expression from TISSUES for TYMP Gene

  • Lung(4.8)
  • Liver(4.5)
  • Nervous system(4.5)
  • Blood(3.3)
  • Intestine(3.1)
  • Lymph node(2.6)
  • Heart(2.4)
  • Muscle(2.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for TYMP Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • digestive
  • integumentary
  • nervous
  • skeletal muscle
  • skeleton
  • urinary
Regions:
Head and neck:
  • brain
  • eye
  • eyelid
  • face
  • head
Thorax:
  • esophagus
Abdomen:
  • intestine
  • kidney
  • large intestine
  • small intestine
  • stomach
Pelvis:
  • rectum
Limb:
  • arm
  • forearm
  • hand
  • lower limb
  • shin
  • thigh
  • upper limb
General:
  • peripheral nerve
  • peripheral nervous system
  • skin
  • spinal cord
genes like me logo Genes that share expression patterns with TYMP: view

No data available for mRNA Expression by UniProt/SwissProt for TYMP Gene

Orthologs for TYMP Gene

This gene was present in the common ancestor of chordates.

Orthologs for TYMP Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TYMP 33 34
  • 98.95 (n)
rat
(Rattus norvegicus)
Mammalia Tymp 33
  • 78.51 (n)
mouse
(Mus musculus)
Mammalia Tymp 33 16 34
  • 78.25 (n)
oppossum
(Monodelphis domestica)
Mammalia TYMP 34
  • 65 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 62 (a)
OneToMany
-- 34
  • 6 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia TYMP 34
  • 57 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tymp 33
  • 56.56 (n)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10042 33
Species where no ortholog for TYMP was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TYMP Gene

ENSEMBL:
Gene Tree for TYMP (if available)
TreeFam:
Gene Tree for TYMP (if available)

Paralogs for TYMP Gene

No data available for Paralogs for TYMP Gene

Variants for TYMP Gene

Sequence variations from dbSNP and Humsavar for TYMP Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1054084896 pathogenic, Mitochondrial DNA depletion syndrome 1 (MNGIE type) 50,529,598(-) C/A coding_sequence_variant, stop_gained
rs1060499532 pathogenic, Mitochondrial DNA depletion syndrome 1 (MNGIE type) 50,526,338(-) A/G coding_sequence_variant, missense_variant
rs1060499533 pathogenic, Mitochondrial DNA depletion syndrome 1 (MNGIE type) 50,526,293(-) A/G coding_sequence_variant, missense_variant
rs1060499534 pathogenic, Mitochondrial DNA depletion syndrome 1 (MNGIE type) 50,526,246(-) C/T coding_sequence_variant, missense_variant
rs1060499535 pathogenic, Mitochondrial DNA depletion syndrome 1 (MNGIE type) 50,526,317(-) CCC/CC coding_sequence_variant, frameshift

Structural Variations from Database of Genomic Variants (DGV) for TYMP Gene

Variant ID Type Subtype PubMed ID
nsv955201 CNV deletion 24416366
nsv834239 CNV loss 17160897
nsv834238 CNV loss 17160897
nsv829340 CNV gain 20364138
nsv589222 CNV gain 21841781
nsv471224 CNV loss 18288195
nsv1160782 CNV deletion 26073780
nsv1057656 CNV gain 25217958
esv3568506 CNV loss 25503493
esv2758852 CNV loss 17122850

Variation tolerance for TYMP Gene

Residual Variation Intolerance Score: 51.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.57; 77.97% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TYMP Gene

Human Gene Mutation Database (HGMD)
TYMP
SNPedia medical, phenotypic, and genealogical associations of SNPs for
TYMP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TYMP Gene

Disorders for TYMP Gene

MalaCards: The human disease database

(34) MalaCards diseases for TYMP Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
mitochondrial dna depletion syndrome 1
  • mtdps1
mitochondrial neurogastrointestinal encephalomyopathy
  • mitochondrial neurogastrointestinal encephalopathy syndrome
mitochondrial neurogastrointestinal encephalopathy disease
  • mngie syndrome
cervical squamous cell carcinoma
  • squamous cell carcinoma of cervix
lymphomatous meningitis
  • meningeal carcinomatosis
- elite association - COSMIC cancer census association via MalaCards
Search TYMP in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

TYPH_HUMAN
  • Mitochondrial DNA depletion syndrome 1, MNGIE type (MTDPS1) [MIM:603041]: A multisystem disease associated with mitochondrial dysfunction. It is clinically characterized by onset between the second and fifth decades of life, ptosis, progressive external ophthalmoplegia, gastrointestinal dysmotility (often pseudoobstruction), diffuse leukoencephalopathy, cachexia, peripheral neuropathy, and myopathy. {ECO:0000269 PubMed:12177387, ECO:0000269 PubMed:9924029}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for TYMP

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with TYMP: view

No data available for Genatlas for TYMP Gene

Publications for TYMP Gene

  1. Platelet-derived endothelial cell growth factor has thymidine phosphorylase activity. (PMID: 1590793) Usuki K … Heldin CH (Biochemical and biophysical research communications 1992) 2 3 4 22 58
  2. Structures of native human thymidine phosphorylase and in complex with 5-iodouracil. (PMID: 19555658) Mitsiki E … Acharya KR (Biochemical and biophysical research communications 2009) 3 4 22 58
  3. Structural basis for non-competitive product inhibition in human thymidine phosphorylase: implications for drug design. (PMID: 16803458) El Omari K … Stammers DK (The Biochemical journal 2006) 3 4 22 58
  4. Altered thymidine metabolism due to defects of thymidine phosphorylase. (PMID: 11733540) Spinazzola A … Hirano M (The Journal of biological chemistry 2002) 2 3 22 58
  5. Genome-wide association study of hematological and biochemical traits in a Japanese population. (PMID: 20139978) Kamatani Y … Kamatani N (Nature genetics 2010) 3 44 58

Products for TYMP Gene