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Aliases for TXNL1 Gene
Aliases for TXNL1 Gene
External Ids for TXNL1 Gene
- HGNC: 12436
- NCBI Entrez Gene: 9352
- Ensembl: ENSG00000091164
- OMIM®: 603049
- UniProtKB/Swiss-Prot: O43396
Previous HGNC Symbols for TXNL1 Gene
- TXNL
Previous GeneCards Identifiers for TXNL1 Gene
- GC18M052420
- GC18M052421
- GC18M054264
- GC18M050981
Summaries for TXNL1 Gene
GeneCards Summary for TXNL1 Gene
TXNL1 (Thioredoxin Like 1) is a Protein Coding gene. Diseases associated with TXNL1 include Dracunculiasis and Human Monocytic Ehrlichiosis. Gene Ontology (GO) annotations related to this gene include protein disulfide oxidoreductase activity and disulfide oxidoreductase activity. An important paralog of this gene is TXN.
UniProtKB/Swiss-Prot Summary for TXNL1 Gene
-
Active thioredoxin with a redox potential of about -250 mV.
Additional gene information for TXNL1 Gene
- HGNC (12436)
- NCBI Entrez Gene (9352)
- Ensembl (ENSG00000091164)
- OMIM® (603049)
- UniProtKB/Swiss-Prot (O43396)
- Open Targets Platform(ENSG00000091164)
- Search for TXNL1 at DataMed
- Search for TXNL1 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TXNL1 Gene
Genomics for TXNL1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TXNL1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TXNL1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TXNL1
- Top Transcription factor binding sites by QIAGEN in the TXNL1 gene promoter:
-
- AP-1
- AREB6
- ATF-2
- c-Jun
- CREB
- deltaCREB
- Meis-1
- Meis-1a
- Meis-1b
- PPAR-gamma2
Genomic Locations for TXNL1 Gene
Latest Assembly
- chr18:56,597,209-56,651,600
- (GRCh38/hg38)
- Size:
- 54,392 bases
- Orientation:
- Minus strand
Previous Assembly
- chr18:54,264,440-54,305,823
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 41,384 bases
- Orientation:
- Minus strand
- chr18:54,264,439-54,318,831
- (GRCh37/hg19 by Ensembl)
- Size:
- 54,393 bases
- Orientation:
- Minus strand
Genomic View for TXNL1 Gene
Genes around TXNL1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 18q21.31 by HGNC
- 18q21.31 by Entrez Gene
- 18q21.31 by Ensembl
TXNL1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TXNL1 Gene
Proteins for TXNL1 Gene
-
Protein details for TXNL1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O43396-TXNL1_HUMAN
- Recommended name:
- Thioredoxin-like protein 1
- Protein Accession:
- O43396
Protein attributes for TXNL1 Gene
- Size:
- 289 amino acids
- Molecular mass:
- 32251 Da
- Quaternary structure:
-
- Component of the 19S regulatory cap of the 26S proteasome. Interacts with PSMD14/RPN11. Interacts with, and reduces EEF1A1.
Protein Expression for TXNL1 Gene
Post-translational modifications for TXNL1 Gene
Other Protein References for TXNL1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
-
Custom Antibody ServicesOriGene Antibodies for TXNL1
- Novus Biologicals Antibodies for TXNL1
-
Abcam antibodies for TXNL1
- Invitrogen Antibodies for TXNL1 (AFLGC-Txnl1)
-
Boster Bio Antibodies for TXNL1
-
Santa Cruz Biotechnology (SCBT) Antibodies for TXNL1
- Sino Biological Antibodies for TXNL1
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for TXNL1
- Origene Custom Protein Services for TXNL1
- ProSpec Recombinant Proteins for TXNL1
-
Abcam proteins for TXNL1
Assay products for research
- antibodies-online: Show 6 available TXNL1 Elisa Kits ranked by validation data
- Compare Top TXNL1 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for TXNL1 Gene
Domains & Families for TXNL1 Gene
Gene Families for TXNL1 Gene
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for TXNL1 Gene
- InterPro:
- Blocks:
-
- Thioredoxin type domain
- ProtoNet:
Suggested Antigen Peptide Sequences for TXNL1 Gene
- GenScript: Design optimal peptide antigens:
-
- 32 kDa thioredoxin-related protein (TXNL1_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TXNL1 Gene
Function for TXNL1 Gene
Molecular function for TXNL1 Gene
- UniProtKB/Swiss-Prot Function:
- Active thioredoxin with a redox potential of about -250 mV.
Phenotypes From GWAS Catalog for TXNL1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0015036 | disulfide oxidoreductase activity | IDA | 9668102 |
Phenotypes for TXNL1 Gene
- GenomeRNAi human phenotypes for TXNL1:
Animal Models for research
-
Taconic Biosciences Mouse Models for TXNL1
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for TXNL1 - Starting at $85 >
- * TXNL1 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for TXNL1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TXNL1
-
Santa Cruz Biotechnology (SCBT) CRISPR for TXNL1
miRNA for TXNL1 Gene
- miRTarBase miRNAs that target TXNL1
-
- mmu-miR-34b-5p (MIRT012842)
- mmu-miR-24-3p (MIRT013980)
- hsa-miR-26a-5p (MIRT050179)
- hsa-miR-16-5p (MIRT051069)
- hsa-miR-6736-3p (MIRT252213)
- hsa-miR-3187-3p (MIRT520405)
- hsa-miR-4435 (MIRT520406)
- hsa-miR-588 (MIRT520407)
- hsa-miR-4701-5p (MIRT520408)
- hsa-miR-548s (MIRT520409)
- hsa-miR-3926 (MIRT520410)
- hsa-miR-422a (MIRT520411)
- hsa-miR-378i (MIRT520412)
- hsa-miR-378h (MIRT520413)
- hsa-miR-378f (MIRT520414)
- hsa-miR-378e (MIRT520415)
- hsa-miR-378d (MIRT520416)
- hsa-miR-378c (MIRT520417)
- hsa-miR-378b (MIRT520418)
- hsa-miR-378a-3p (MIRT520419)
- hsa-miR-3653-5p (MIRT520420)
- hsa-miR-320e (MIRT520421)
- hsa-miR-569 (MIRT532549)
- hsa-miR-3659 (MIRT532550)
- hsa-miR-455-5p (MIRT532551)
- hsa-miR-8066 (MIRT532552)
- hsa-miR-3156-5p (MIRT532553)
- hsa-miR-378a-5p (MIRT532554)
- hsa-miR-6821-3p (MIRT532555)
- hsa-miR-6790-3p (MIRT532556)
- hsa-miR-7978 (MIRT532557)
- hsa-miR-4456 (MIRT532558)
- hsa-miR-548q (MIRT532559)
- hsa-miR-4299 (MIRT532560)
- hsa-miR-6764-3p (MIRT532561)
- hsa-miR-6824-3p (MIRT532562)
- hsa-miR-548z (MIRT621412)
- hsa-miR-548h-3p (MIRT621413)
- hsa-miR-548d-3p (MIRT621414)
- hsa-miR-548bb-3p (MIRT621415)
- hsa-miR-548ac (MIRT621416)
- hsa-miR-6836-3p (MIRT641728)
- hsa-miR-5001-3p (MIRT641729)
- hsa-miR-3157-5p (MIRT641730)
- hsa-miR-6829-3p (MIRT641731)
- hsa-miR-6791-3p (MIRT641732)
- hsa-miR-6778-3p (MIRT641733)
- hsa-miR-4772-3p (MIRT641734)
- hsa-miR-6787-3p (MIRT641735)
- hsa-miR-1304-3p (MIRT641736)
- hsa-miR-4532 (MIRT641737)
- hsa-miR-1247-3p (MIRT641738)
- hsa-miR-6890-3p (MIRT641739)
- hsa-miR-640 (MIRT665561)
- hsa-miR-6720-5p (MIRT665562)
- hsa-miR-6512-3p (MIRT665563)
- hsa-miR-371a-5p (MIRT665564)
- hsa-miR-616-5p (MIRT665565)
- hsa-miR-373-5p (MIRT665566)
- hsa-miR-371b-5p (MIRT665567)
- hsa-miR-6849-3p (MIRT665568)
- hsa-miR-6513-3p (MIRT665569)
- hsa-miR-5586-5p (MIRT665570)
- hsa-miR-8079 (MIRT665571)
- hsa-miR-1245a (MIRT665572)
- hsa-miR-6746-3p (MIRT665573)
- hsa-miR-4279 (MIRT715283)
- hsa-miR-6883-3p (MIRT715284)
- hsa-miR-6837-3p (MIRT715285)
- hsa-miR-130b-5p (MIRT715286)
- hsa-miR-205-5p (MIRT715287)
- hsa-miR-6891-3p (MIRT724939)
- hsa-miR-6826-3p (MIRT724940)
- hsa-miR-452-3p (MIRT724941)
- hsa-miR-4539 (MIRT724942)
- hsa-miR-146a-3p (MIRT724943)
- hsa-miR-2276-5p (MIRT724944)
- hsa-miR-6795-3p (MIRT724945)
- hsa-miR-6887-3p (MIRT724946)
- hsa-miR-664a-3p (MIRT724947)
- hsa-miR-141-5p (MIRT724948)
- hsa-miR-6074 (MIRT724949)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TXNL1
- Browse OriGene Inhibitory RNA Products For TXNL1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TXNL1
Clone products for research
- Applied Biological Materials (abm): Clones for TXNL1 - Starting at $45 >
- * TXNL1 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for TXNL1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TXNL1
Cell Lines for research
-
Horizon Cell Lines for TXNL1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TXNL1 Gene
Localization for TXNL1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TXNL1 Gene
- Cytoplasm. Nucleus. Note=At least 85% of the cellular TXNL1 is proteasome-associated.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 4 |
| mitochondrion | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Cytosol (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000502 | proteasome complex | IEA | -- |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005737 | cytoplasm | IEA,IDA | 9668102 |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for TXNL1 Gene
Interacting Proteins for TXNL1 Gene
GPS-Prot Interaction Network for TXNL1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0045454 | cell redox homeostasis | IEA | -- |
| GO:0055114 | oxidation-reduction process | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for TXNL1 Gene
Transcripts for TXNL1 Gene
mRNA/cDNA for TXNL1 Gene
- 1 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 11 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000217515 6840 nts (view in UCSC)
- ENST00000585497 1647 nts (view in UCSC)
- ENST00000586079 502 nts (view in UCSC)
- ENST00000586262 3541 nts (view in UCSC)
- ENST00000587613 934 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for TXNL1 - Starting at $85 >
- * TXNL1 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for TXNL1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TXNL1
-
Santa Cruz Biotechnology (SCBT) CRISPR for TXNL1
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TXNL1
- Browse OriGene Inhibitory RNA Products For TXNL1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TXNL1
Clone products for research
- Applied Biological Materials (abm): Clones for TXNL1 - Starting at $45 >
- * TXNL1 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for TXNL1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TXNL1
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||||
| SP6: | - |
Relevant External Links for TXNL1 Gene
- GeneLoc Exon Structure for
- TXNL1
Expression for TXNL1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
- Intestine (Gastrointestinal Tract)
- Pancreas (Endocrine System)
- Ovary (Reproductive System)
- Blood (Hematopoietic System)
-
Thyroid (Endocrine System)
-
Adrenal Gland (Endocrine System)
-
Esophagus (Gastrointestinal Tract)
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TXNL1 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TXNL1
SOURCE GeneReport for Unigene cluster for TXNL1 Gene:
Hs.114412mRNA Expression by UniProt/SwissProt for TXNL1 Gene:
O43396-TXNL1_HUMAN
Tissue specificity:
Ubiquitous.
Evidence on tissue expression from TISSUES for TXNL1 Gene
- Nervous system(4.8)
- Blood(4.5)
- Lung(4.4)
- Liver(4.4)
- Thyroid gland(2.4)
- Kidney(2.3)
- Heart(2.2)
- Muscle(2.2)
- Skin(2.1)
- Spleen(2)
- Intestine(2)
Primer products for research
-
OriGene qPCR primer pairs for TXNL1
-
OriGene qPCR primer pairs and template standards for TXNL1
Gene Expression Assays for research
No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for TXNL1 Gene
Orthologs for TXNL1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TXNL1 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | TXNL1 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | TXNL1 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | TXNL1 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Txnl1 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Txnl1 30 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | TXNL1 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | TXNL1 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | TXNL1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | txnl1 30 |
|
||
| Str.5938 30 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | txnl1 30 31 |
|
OneToOne | |
| zgc55368 30 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.10705 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Txl 30 31 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005462 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | Y54E10A.3 30 31 |
|
OneToMany | |
| Y55F3AR.2 31 |
|
OneToMany | |||
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | TRX1 31 |
|
ManyToMany | |
| TRX2 31 |
|
ManyToMany | |||
| TRX3 31 |
|
ManyToMany | |||
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT3G04780 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os03g0795500 30 |
|
||
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | txl1 30 |
|
||
| Bread mold (Neurospora crassa) |
Ascomycetes | NCU02520 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.2149 31 |
|
OneToOne |
- Species where no ortholog for TXNL1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for TXNL1 Gene
- ENSEMBL:
- Gene Tree for TXNL1 (if available)
- TreeFam:
- Gene Tree for TXNL1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TXNL1: view image
Paralogs for TXNL1 Gene
(2) SIMAP similar genes for TXNL1 Gene using alignment to 7 proteins:
- TXNL1_HUMAN
- G3V1K0_HUMAN
- K7EKG2_HUMAN
- K7EME7_HUMAN
- K7EML9_HUMAN
- K7EPB7_HUMAN
- K7ER96_HUMAN
Pseudogenes.org Pseudogenes for TXNL1 Gene
Variants for TXNL1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TXNL1 Gene
| SNP ID | Clinical significance and condition | Chr 18 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs145097903 | Benign: not provided | 56,616,312(-) |
C/G NM_004786.3(TXNL1):c.495G>C (p.Leu165=) |
NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS | |
| rs17090267 | Benign: not provided | 56,614,600(-) |
T/C NM_004786.3(TXNL1):c.563-4A>G |
INTRON | |
| rs746905367 | Likely Benign: not provided | 56,626,373(-) |
T/A NM_004786.3(TXNL1):c.183A>T (p.Val61=) |
NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv3359n100 | CNV | gain | 25217958 |
| nsv1062964 | CNV | gain | 25217958 |
| nsv577020 | CNV | gain | 21841781 |
Residual Variation Intolerance Score:
37.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.58;
12.45% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TXNL1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TXNL1
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TXNL1 Gene
Disorders for TXNL1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| dracunculiasis |
|
|
| human monocytic ehrlichiosis |
|
|
| ehrlichiosis |
|
|
Search TXNL1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TXNL1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for TXNL1 Gene
Publications for TXNL1 Gene
- Purification, molecular cloning, and characterization of TRP32, a novel thioredoxin-related mammalian protein of 32 kDa. (PMID: 9668102) Lee KK … Yonehara S (The Journal of biological chemistry 1998) 2 3 4 23
- Molecular cloning and expression of a cDNA encoding a human thioredoxin-like protein. (PMID: 9473519) Miranda-Vizuete A … Spyrou G (Biochemical and biophysical research communications 1998) 2 3 4 23
- Solution structure of the C-terminal DUF1000 domain of the human thioredoxin-like 1 protein. (PMID: 20455272) Goroncy AK … Yokoyama S (Proteins 2010) 3 4 23
- Thioredoxin Txnl1/TRP32 is a redox-active cofactor of the 26 S proteasome. (PMID: 19349277) Andersen KM … Hartmann-Petersen R (The Journal of biological chemistry 2009) 3 4 23
- Genomic structure and chromosomal localization of human thioredoxin-like protein gene (txl). (PMID: 10826702) Miranda-Vizuete A … Spyrou G (DNA sequence : the journal of DNA sequencing and mapping 2000) 3 4 23
ExternalLinks
Products for TXNL1 Gene
- Custom Antibody ServicesOriGene Antibodies for TXNL1
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for TXNL1
- Origene Custom Protein Services for TXNL1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TXNL1
- Browse OriGene Inhibitory RNA Products For TXNL1
- OriGene qPCR primer pairs for TXNL1
- OriGene qPCR primer pairs and template standards for TXNL1
- OriGene CRISPR knockouts for TXNL1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TXNL1
- Sino Biological Human cDNA Clone for TXNL1
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for TXNL1
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for TXNL1
- Novus Biologicals proteins and lysates for TXNL1
- Browse Antibodies
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- Abcam antibodies for TXNL1
- Abcam proteins for TXNL1
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- Browse Primary Antibodies
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- ProSpec Recombinant Proteins for TXNL1
- Taconic Biosciences Mouse Models for TXNL1
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for TXNL1 (AFLGC-Txnl1)
- VectorBuilder Custom and pre-made DNA vectors for TXNL1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for TXNL1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for TXNL1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for TXNL1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for TXNL1
- antibodies-online: Show 17 available TXNL1 Antibodies ranked by validation data
- Compare Top TXNL1 Antibodies
- antibodies-online: Show 6 available TXNL1 Elisa Kits ranked by validation data
- Compare Top TXNL1 Elisa Kits
- Quality Products:
- antibodies-online: Show 10 available TXNL1 Proteins ranked by validation data
- Compare Top TXNL1 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for TXNL1
- Search Santa Cruz Biotechnology (SCBT) for TXNL1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for TXNL1
- Horizon Cell Lines for TXNL1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TXNL1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TXNL1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for TXNL1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TXNL1
- Boster Bio Antibodies for TXNL1
- Browse Boster Bio ELISA Kits
Sources for TXNL1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB