Aliases for TUT4 Gene
Aliases for TUT4 Gene
External Ids for TUT4 Gene
- HGNC: 28981
- Entrez Gene: 23318
- Ensembl: ENSG00000134744
- OMIM: 613692
- UniProtKB: Q5TAX3
Previous HGNC Symbols for TUT4 Gene
- ZCCHC11
Summaries for TUT4 Gene
-
ZCCHC11 is an RNA uridyltransferase (EC 2.7.7.52) that uses UTP to add uridines to the 3-prime end of substrate RNA molecules (Jones et al., 2009 [PubMed 19701194]).[supplied by OMIM, Jan 2011]
GeneCards Summary for TUT4 Gene
TUT4 (Terminal Uridylyl Transferase 4) is a Protein Coding gene. An important paralog of this gene is TUT7.
UniProtKB/Swiss-Prot for TUT4 Gene
-
Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay (PubMed:25480299). Involved in microRNA (miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets. Also acts as a suppressor of miRNA biogenesis by mediating the terminal uridylation of some miRNA precursors, including that of let-7 (pre-let-7), miR107, miR-143 and miR-200c. Uridylated miRNAs are not processed by Dicer and undergo degradation. Degradation of pre-let-7 contributes to the maintenance of embryonic stem (ES) cell pluripotency (By similarity). Does not bind RNA directly, but recruited to RNA targets by RNA-binding protein LIN28A. Also catalyzes the 3 uridylation of miR-26A, a miRNA that targets IL6 transcript. This abrogates the silencing of IL6 transcript, hence promoting cytokine expression (By similarity). May also suppress Toll-like receptor-induced NF-kappa-B activation via binding to T2BP. Does not play a role in replication-dependent histone mRNA degradation. Due to functional redundancy between ZCCHC6 and ZCCHC11, the identification of the specific role of each of these proteins is difficult.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TUT4 Gene
Genomics for TUT4 Gene
GeneHancer (GH) Regulatory Elements for TUT4 Gene
Promoters and enhancers for TUT4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around TUT4 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for TUT4 Gene
Genomic Locations for TUT4 Gene
- chr1:52,408,282-52,553,487
- (GRCh38/hg38)
- Size:
- 145,206 bases
- Orientation:
- Minus strand
- chr1:52,873,954-53,019,159
- (GRCh37/hg19)
- Size:
- 145,206 bases
- Orientation:
- Minus strand
Genomic View for TUT4 Gene
Genes around TUT4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p32.3 by Entrez Gene
- 1p32.3 by HGNC
- 1p32.3 by Ensembl
TUT4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TUT4 Gene
Proteins for TUT4 Gene
-
Protein details for TUT4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5TAX3-TUT4_HUMAN
- Recommended name:
- Terminal uridylyltransferase 4
- Protein Accession:
- Q5TAX3
- A2RRP0
- B7Z8J5
- D3DQ35
- Q12764
- Q5TAX2
- Q5TAX4
- Q86XZ3
Protein attributes for TUT4 Gene
- Size:
- 1644 amino acids
- Molecular mass:
- 185166 Da
- Cofactor:
- Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
- Quaternary structure:
-
- Interacts with LIN28A in the presence of pre-let-7 RNA. Interacts with T2BP.
- SequenceCaution:
-
- Sequence=CAI23477.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Post-translational modifications for TUT4 Gene
Other Protein References for TUT4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- XP_006710562.1
- XP_011539399.1
- XP_006710561.1
- NP_056084.1
- XP_005270735.1
- XP_016856304.1
- XP_016856307.1
- XP_016856302.1
- XP_011539402.1
- XP_016856294.1
- XP_005270738.1
- XP_016856297.1
- XP_011539401.1
- XP_006710563.1
- XP_016856292.1
- XP_016856298.1
- XP_005270733.1
- XP_016856305.1
- XP_016856300.1
- NP_001009881.1
- XP_005270740.1
- XP_016856303.1
- XP_011539403.1
- XP_005270736.1
- XP_016856295.1
- XP_005270739.1
- XP_016856293.1
- XP_016856299.1
- XP_016856306.1
- XP_016856301.1
- XP_011539400.1
- XP_005270737.1
- XP_016856296.1
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for TUT4
- Novus Biologicals Antibodies for TUT4
-
Abcam antibodies for TUT4
- Invitrogen Antibodies for TUT4
- GeneTex ZCCHC11 Antibody for TUT4
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TUT4
- Origene Custom Protein Services for TUT4
- Search GeneTex for Proteins for TUT4
-
Abcam proteins for TUT4
Assay Products
No data available for DME Specific Peptides for TUT4 Gene
Domains & Families for TUT4 Gene
Gene Families for TUT4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for TUT4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for TUT4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q5TAX3- Family:
-
- Belongs to the DNA polymerase type-B-like family.
Function for TUT4 Gene
Molecular function for TUT4 Gene
- UniProtKB/Swiss-Prot Function:
- Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay (PubMed:25480299). Involved in microRNA (miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets. Also acts as a suppressor of miRNA biogenesis by mediating the terminal uridylation of some miRNA precursors, including that of let-7 (pre-let-7), miR107, miR-143 and miR-200c. Uridylated miRNAs are not processed by Dicer and undergo degradation. Degradation of pre-let-7 contributes to the maintenance of embryonic stem (ES) cell pluripotency (By similarity). Does not bind RNA directly, but recruited to RNA targets by RNA-binding protein LIN28A. Also catalyzes the 3 uridylation of miR-26A, a miRNA that targets IL6 transcript. This abrogates the silencing of IL6 transcript, hence promoting cytokine expression (By similarity). May also suppress Toll-like receptor-induced NF-kappa-B activation via binding to T2BP. Does not play a role in replication-dependent histone mRNA degradation. Due to functional redundancy between ZCCHC6 and ZCCHC11, the identification of the specific role of each of these proteins is difficult.
- UniProtKB/Swiss-Prot CatalyticActivity:
- UTP + RNA(n) = diphosphate + RNA(n+1).
Enzyme Numbers (IUBMB) for TUT4 Gene
Phenotypes From GWAS Catalog for TUT4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003723 | RNA binding | HDA | 22658674 |
| GO:0005515 | protein binding | IPI | 19703396 |
| GO:0008270 | zinc ion binding | IEA | -- |
| GO:0016740 | transferase activity | IEA | -- |
Phenotypes for TUT4 Gene
- MGI mutant phenotypes for TUT4:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for TUT4:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for TUT4
-
CRISPR Products
-
OriGene CRISPR knockouts for TUT4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TUT4
- genomics-online: gRNA clones - Search results for available ZCCHC11 gene related products
- Applied Biological Materials CRISPR for TUT4
-
Vectors and viruses for KO, Activation, Repression, and more
- GenScript: Design CRISPR guide RNA sequences for TUT4
miRNA for TUT4 Gene
- miRTarBase miRNAs that target TUT4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TUT4
- Browse OriGene Inhibitory RNA Products For TUT4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TUT4
- genomics-online: shRNA clones - Search results for available ZCCHC11 gene related products
Clone Products
-
GenScript: Next-day shipping of latest version cDNA ORF clones for TUT4 in any vector
- XM_006710499.3
- XM_005270678.2
- XM_005270680.2
- NM_015269.2
- XM_005270683.2
- XM_005270676.2
- XM_005270679.2
- NM_001009881.2
- XM_011541100.2
- XM_005270682.2
- XM_006710498.2
- XM_005270681.2
- XM_011541101.2
- XM_011541098.1
- XM_017000810.1
- XM_017000817.1
- XM_017000815.1
- XM_017000803.1
- XM_017000806.1
- XM_011541097.1
- XM_006710500.1
- XM_011541099.1
- XM_017000808.1
- XM_017000814.1
- XM_017000816.1
- XM_017000805.1
- XM_017000812.1
- XM_017000813.1
- XM_017000804.1
- XM_017000807.1
- XM_017000809.1
- XM_017000811.1
- XM_017000818.1
- Sino Biological Human cDNA Clone for TUT4
- VectorBuilder custom plasmid, inducible vectors for TUT4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TUT4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TUT4
- genomics-online: cdna clones - Search results for available ZCCHC11 gene related products
- orf clones - Search results for available ZCCHC11 gene related products
- Applied Biological Materials Clones for TUT4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for TUT4
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TUT4 Gene
Localization for TUT4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TUT4 Gene
- Nucleus. Cytoplasm. Note=Mainly cytoplasmic (PubMed:19703396, PubMed:25480299). Translocates into the cytoplasm following treatment of the cell with LPS (PubMed:16643855).
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| cytosol | 5 |
- Cytosol (3)
- Nucleoli (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005615 | extracellular space | HDA | 22664934 |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005730 | nucleolus | IDA | -- |
| GO:0005737 | cytoplasm | IEA,IDA | 19703396 |
| GO:0005829 | cytosol | TAS,IDA | -- |
Pathways & Interactions for TUT4 Gene
No Data Available
Interacting Proteins for TUT4 Gene
Selected Interacting proteins:
Q5TAX3-TUT4_HUMAN
ENSP00000257177
for TUT4 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for TUT4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening | TAS | -- |
| GO:0001816 | cytokine production | IEA | -- |
| GO:0010586 | miRNA metabolic process | ISS | -- |
| GO:0010587 | miRNA catabolic process | IMP | 19703396 |
| GO:0019827 | stem cell population maintenance | IMP | 19703396 |
No data available for Pathways by source and SIGNOR curated interactions for TUT4 Gene
Drugs & Compounds for TUT4 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Uridine triphosphate | Experimental, Investigational | Pharma | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| pyrophosphate |
|
14000-31-8 |
|
Drug Products
Transcripts for TUT4 Gene
mRNA/cDNA for TUT4 Gene
- (34) REFSEQ mRNAs :
- (160) Selected AceView cDNA sequences:
- (21) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000257177 5743 bps (uc001cty.3)
- ENST00000371544 5858 bps (uc001ctx.3)
- ENST00000466440 5763 bps (uc057goj.1)
- ENST00000494469 827 bps (uc057gok.1)
- ENST00000471623 506 bps (uc057gol.1)
CRISPR Products
-
OriGene CRISPR knockouts for TUT4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TUT4
- genomics-online: gRNA clones - Search results for available ZCCHC11 gene related products
- Applied Biological Materials CRISPR for TUT4
-
Vectors and viruses for KO, Activation, Repression, and more
- GenScript: Design CRISPR guide RNA sequences for TUT4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TUT4
- Browse OriGene Inhibitory RNA Products For TUT4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TUT4
- genomics-online: shRNA clones - Search results for available ZCCHC11 gene related products
Clone Products
-
GenScript: Next-day shipping of latest version cDNA ORF clones for TUT4 in any vector
- XM_006710499.3
- XM_005270678.2
- XM_005270680.2
- NM_015269.2
- XM_005270683.2
- XM_005270676.2
- XM_005270679.2
- NM_001009881.2
- XM_011541100.2
- XM_005270682.2
- XM_006710498.2
- XM_005270681.2
- XM_011541101.2
- XM_011541098.1
- XM_017000810.1
- XM_017000817.1
- XM_017000815.1
- XM_017000803.1
- XM_017000806.1
- XM_011541097.1
- XM_006710500.1
- XM_011541099.1
- XM_017000808.1
- XM_017000814.1
- XM_017000816.1
- XM_017000805.1
- XM_017000812.1
- XM_017000813.1
- XM_017000804.1
- XM_017000807.1
- XM_017000809.1
- XM_017000811.1
- XM_017000818.1
- Sino Biological Human cDNA Clone for TUT4
- VectorBuilder custom plasmid, inducible vectors for TUT4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TUT4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TUT4
- genomics-online: cdna clones - Search results for available ZCCHC11 gene related products
- orf clones - Search results for available ZCCHC11 gene related products
- Applied Biological Materials Clones for TUT4
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for TUT4 Gene
NURSA nuclear receptor signaling pathways regulating expression of TUT4 Gene:
TUT4Evidence on tissue expression from TISSUES for TUT4 Gene
- Bone marrow(4.2)
- Nervous system(2.9)
No Expression Related Data Available
Primer Products
-
OriGene qPCR primer pairs for TUT4
- genomics-online: primer clones - Search results for available ZCCHC11 gene related products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TUT4 Gene
Orthologs for TUT4 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ZCCHC11 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | ZCCHC11 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | LOC528986 33 |
|
||
| ZCCHC11 34 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Zcchc11 34 33 |
|
OneToOne | |
| Tut4 16 |
|
||||
| rat (Rattus norvegicus) |
Mammalia | Zcchc11 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ZCCHC11 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ZCCHC11 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ZCCHC11 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | ZCCHC11 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | zcchc11 33 |
|
||
| Str.15797 33 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | LOC795358 33 |
|
||
| zcchc11 34 |
|
OneToOne | |||
| Dr.17857 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | mkg-p 34 |
|
ManyToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | pup-2 34 |
|
ManyToMany | |
| cid-1 34 |
|
ManyToMany | |||
| Y34F4.3 34 |
|
ManyToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.5065 34 |
|
OneToMany | |
| Cin.4240 33 |
|
||||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.4240 33 |
|
- Species where no ortholog for TUT4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for TUT4 Gene
- ENSEMBL:
- Gene Tree for TUT4 (if available)
- TreeFam:
- Gene Tree for TUT4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TUT4: view image
Paralogs for TUT4 Gene
Variants for TUT4 Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000027586 | -- | 52,517,129(-) | C/T | intron_variant | |
| rs1000029564 | -- | 52,553,171(-) | G/A | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000034878 | -- | 52,510,864(-) | C/G | intron_variant | |
| rs1000037070 | -- | 52,426,172(-) | A/G | genic_downstream_transcript_variant, intron_variant | |
| rs1000048446 | -- | 52,425,357(-) | T/C | coding_sequence_variant, genic_downstream_transcript_variant, missense_variant, non_coding_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3586051 | CNV | loss | 21293372 |
| esv988243 | CNV | insertion | 20482838 |
| nsv1137759 | CNV | deletion | 24896259 |
Residual Variation Intolerance Score:
2.47% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.40;
54.25% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TUT4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TUT4
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TUT4 Gene
Disorders for TUT4 Gene
Additional Disease Information for TUT4
No disorders were found for TUT4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TUT4 Gene
Publications for TUT4 Gene
- Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PMID: 8724849) Nagase T … Nomura N (DNA research : an international journal for rapid publication of reports on genes and genomes 1996) 2 3 4 58
- Uridylation by TUT4 and TUT7 marks mRNA for degradation. (PMID: 25480299) Lim J … Kim VN (Cell 2014) 3 4 58
- TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. (PMID: 19703396) Heo I … Kim VN (Cell 2009) 3 4 58
- Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'. (PMID: 18172165) Mullen TE … Marzluff WF (Genes & development 2008) 3 4 58
- A novel Zinc finger protein, ZCCHC11, interacts with TIFA and modulates TLR signaling. (PMID: 16643855) Minoda Y … Yoshimura A (Biochemical and biophysical research communications 2006) 3 4 58
Products for TUT4 Gene
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- Browse R&D Systems for biochemical assays
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- Browse ELISAs
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- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for TUT4
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TUT4
- Origene Custom Protein Services for TUT4
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TUT4
- Browse OriGene Inhibitory RNA Products For TUT4
- OriGene qPCR primer pairs for TUT4
- OriGene CRISPR knockouts for TUT4
- OriGene ORF clones in human for TUT4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TUT4
- GenScript: Next-day shipping of latest version cDNA ORF clones for TUT4 in any vector
- XM_006710499.3
- XM_005270678.2
- XM_005270680.2
- NM_015269.2
- XM_005270683.2
- XM_005270676.2
- XM_005270679.2
- NM_001009881.2
- XM_011541100.2
- XM_005270682.2
- XM_006710498.2
- XM_005270681.2
- XM_011541101.2
- XM_011541098.1
- XM_017000810.1
- XM_017000817.1
- XM_017000815.1
- XM_017000803.1
- XM_017000806.1
- XM_011541097.1
- XM_006710500.1
- XM_011541099.1
- XM_017000808.1
- XM_017000814.1
- XM_017000816.1
- XM_017000805.1
- XM_017000812.1
- XM_017000813.1
- XM_017000804.1
- XM_017000807.1
- XM_017000809.1
- XM_017000811.1
- XM_017000818.1
- GenScript Custom Purified and Recombinant Proteins Services for TUT4
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- GenScript: Design CRISPR guide RNA sequences for TUT4
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- Sino Biological Human cDNA Clone for TUT4
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- High-throughput Antibody Production Service
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- Epitope Tag Antibodies & Reporter Protein Antibodies
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- Novus Biologicals Antibodies for TUT4
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- Novus Biologicals
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- Browse Primary Antibodies
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- Search Knockout (KO) Validated Antibodies
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- Browse Recombinant Antibodies
- VectorBuilder custom plasmid, inducible vectors for TUT4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TUT4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 56 available ZCCHC11 Antibodies ranked by validation data
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- antibodies-online: Search results for available ZCCHC11 related products ranked by validation data
- antibodies-online: Search results for 3 available ZCCHC11 Proteins ranked by validation data
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- GeneTex ZCCHC11 Antibody for TUT4
- Search GeneTex for Proteins for TUT4
- Horizon Cell Lines for TUT4
- genomics-online: cdna clones - Search results for available ZCCHC11 gene related products
- orf clones - Search results for available ZCCHC11 gene related products
- genomics-online: gRNA clones - Search results for available ZCCHC11 gene related products
- genomics-online: primer clones - Search results for available ZCCHC11 gene related products
- genomics-online: shRNA clones - Search results for available ZCCHC11 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TUT4
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Sources for TUT4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt