Aliases for TUSC8 Gene

Subcategory (RNA class) for TUSC8 Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for TUSC8 Gene

  • Tumor Suppressor Candidate 8 2 3 5
  • Tumor Suppressor Candidate 8 (Non-Protein Coding) 2 3
  • Long Intergenic Non-Protein Coding RNA 1071 2 3
  • TUSC8 2 168
  • NONHSAG013388 92
  • HSALNG0096756 167
  • XLOC_010588 3
  • LINC01071 3

External Ids for TUSC8 Gene

Previous HGNC Symbols for TUSC8 Gene

  • LINC01071

Previous GeneCards Identifiers for TUSC8 Gene

  • GC13U901084

Summaries for TUSC8 Gene

GeneCards Summary for TUSC8 Gene

TUSC8 (Tumor Suppressor Candidate 8) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with TUSC8 include Cervical Cancer and Colorectal Cancer.

Additional gene information for TUSC8 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TUSC8 Gene

Genomics for TUSC8 Gene

GeneHancer (GH) Regulatory Elements for TUSC8 Gene

Promoters and enhancers for TUSC8 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13J044411 Enhancer 0.4 Ensembl 505.9 -1.8 -1815 2 HNRNPK PCBP1 GATA2 PCBP2 TUSC8 piR-35564-037 piR-58297-130 SERP2
GH13J044402 Promoter/Enhancer 1.6 Ensembl ENCODE CraniofacialAtlas 9.3 +5.5 5534 6.1 EP300 POLR2G NCOR1 TEAD4 ZIC2 KDM6A TCF7 ZNF623 FOXA1 TGIF2 piR-47103 SERP2 ENSG00000273149 TPT1-AS1 RCN1P2 TUSC8 FJ601684-100
GH13J044396 Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas 7.3 +13.5 13485 2.6 PHB2 ZIC2 ZBTB11 AFF1 TARDBP DNMT1 HES1 TOE1 MYC MXI1 TUSC8 piR-47103 HSALNG0096754 LOC105370297 SERP2
GH13J044362 Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas 7.4 +46.7 46727 4.1 KDM6A TCF7 FOXA1 RFX1 CUX1 EP300 SKI TEAD1 TBX3 FOXA2 TUSC8 ENSG00000277831 RF00951-032
GH13J044359 Enhancer 0.9 Ensembl ENCODE 8 +50.4 50375 2.8 JUND FOS MYC NCOR1 NFIC FOSL2 JUN FOSL1 STAT3 EP300 TUSC8 ENSG00000277831 RF00951-032
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TUSC8 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TUSC8 Gene

Genomic Locations for TUSC8 Gene
chr13:44,397,725-44,410,786
(GRCh38/hg38)
Size:
13,062 bases
Orientation:
Minus strand

Genomic View for TUSC8 Gene

Genes around TUSC8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TUSC8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TUSC8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TUSC8 Gene

Proteins for TUSC8 Gene

Post-translational modifications for TUSC8 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TUSC8 Gene

Domains & Families for TUSC8 Gene

Gene Families for TUSC8 Gene

genes like me logo Genes that share domains with TUSC8: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TUSC8 Gene

Function for TUSC8 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TUSC8 Gene

Localization for TUSC8 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TUSC8 Gene

Pathways & Interactions for TUSC8 Gene

PathCards logo

SuperPathways for TUSC8 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for TUSC8 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for TUSC8 Gene

Drugs & Compounds for TUSC8 Gene

No Compound Related Data Available

Transcripts for TUSC8 Gene

mRNA/cDNA for TUSC8 Gene

19 RNACentral transcripts :
1 REFSEQ mRNAs :
2 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
6 NONCODE transcripts :
12 LncBook transcripts :
16 LNCipedia transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for TUSC8 Gene

No ASD Table

Relevant External Links for TUSC8 Gene

GeneLoc Exon Structure for
TUSC8

Expression for TUSC8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TUSC8 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TUSC8

genes like me logo Genes that share expression patterns with TUSC8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TUSC8 Gene

Orthologs for TUSC8 Gene

Evolution for TUSC8 Gene

ENSEMBL:
Gene Tree for TUSC8 (if available)
TreeFam:
Gene Tree for TUSC8 (if available)

No data available for Orthologs for TUSC8 Gene

Paralogs for TUSC8 Gene

No data available for Paralogs for TUSC8 Gene

Variants for TUSC8 Gene

Additional dbSNP identifiers (rs#s) for TUSC8 Gene

Additional Variant Information for TUSC8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TUSC8

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TUSC8 Gene

Disorders for TUSC8 Gene

MalaCards: The human disease database

(2) MalaCards diseases for TUSC8 Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
cervical cancer
  • cervical cancer, somatic
colorectal cancer
  • crc
- elite association - COSMIC cancer census association via MalaCards
Search TUSC8 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for TUSC8

genes like me logo Genes that share disorders with TUSC8: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TUSC8 Gene

Publications for TUSC8 Gene

  1. Low expression of long noncoding XLOC_010588 indicates a poor prognosis and promotes proliferation through upregulation of c-Myc in cervical cancer. (PMID: 24667250) Liao LM … Huang L (Gynecologic oncology 2014) 2 3 54
  2. LncRNA TUSC8 inhibits the invasion and migration of cervical cancer cells via miR-641/PTEN axis. (PMID: 31033083) Zhu Y … Wang L (Cell biology international 2019) 3 54
  3. Downregulation of the long non-coding RNA XLOC_010588 inhibits the invasion and migration of colorectal cancer. (PMID: 29436686) Li Y … Sun M (Oncology reports 2018) 3 54
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 54
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 54

Products for TUSC8 Gene

Sources for TUSC8 Gene