Aliases for TUBG2 Gene
External Ids for TUBG2 Gene
Previous GeneCards Identifiers for TUBG2 Gene
GeneCards Summary for TUBG2 Gene
TUBG2 (Tubulin Gamma 2) is a Protein Coding gene. Diseases associated with TUBG2 include Childhood Pilocytic Astrocytoma. Among its related pathways are Cell Cycle, Mitotic and Regulation of PLK1 Activity at G2/M Transition. Gene Ontology (GO) annotations related to this gene include GTP binding and structural molecule activity. An important paralog of this gene is TUBG1.
UniProtKB/Swiss-Prot Summary for TUBG2 Gene
Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).
Microtubules are cylindrical tubes of 20-25 nm in diameter. They are composed of protofilaments which are in turn composed of alpha- and beta-tubulin polymers. Each microtubule is polarized; at one end alpha-subunits are exposed (-) and at the other, beta-subunits are exposed (+).