Aliases for TUBD1 Gene
Aliases for TUBD1 Gene
External Ids for TUBD1 Gene
- HGNC: 16811
- Entrez Gene: 51174
- Ensembl: ENSG00000108423
- OMIM: 607344
- UniProtKB: Q9UJT1
Previous GeneCards Identifiers for TUBD1 Gene
- GC17M057786
- GC17M060386
- GC17M058278
- GC17M058412
- GC17M055291
- GC17M057936
- GC17M053309
Summaries for TUBD1 Gene
GeneCards Summary for TUBD1 Gene
TUBD1 (Tubulin Delta 1) is a Protein Coding gene. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and ERK Signaling. Gene Ontology (GO) annotations related to this gene include GTP binding and structural constituent of cytoskeleton. An important paralog of this gene is TUBE1.
UniProtKB/Swiss-Prot for TUBD1 Gene
-
Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
-
Microtubules are cylindrical tubes of 20-25 nm in diameter. They are composed of protofilaments which are in turn composed of alpha- and beta-tubulin polymers. Each microtubule is polarized; at one end alpha-subunits are exposed (-) and at the other, beta-subunits are exposed (+).
Additional gene information for TUBD1 Gene
- Monarch Initiative
- Search for TUBD1 at DataMed
- Search for TUBD1 at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TUBD1 Gene
Genomics for TUBD1 Gene
GeneHancer (GH) Regulatory Elements for TUBD1 Gene
Promoters and enhancers for TUBD1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around TUBD1 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for TUBD1 Gene
Genomic Locations for TUBD1 Gene
- chr17:59,859,479-59,892,945
- (GRCh38/hg38)
- Size:
- 33,467 bases
- Orientation:
- Minus strand
- chr17:57,936,840-57,970,306
- (GRCh37/hg19)
Genomic View for TUBD1 Gene
Genes around TUBD1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q23.1 by Entrez Gene
- 17q23.1 by HGNC
- 17q23.1 by Ensembl
TUBD1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TUBD1 Gene
Proteins for TUBD1 Gene
-
Protein details for TUBD1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UJT1-TBD_HUMAN
- Recommended name:
- Tubulin delta chain
- Protein Accession:
- Q9UJT1
- B4DPT8
- B4DW01
- D3DU02
- E9PCA7
- E9PCQ8
- Q5KU36
- Q9BWG9
- Q9H7Z8
Protein attributes for TUBD1 Gene
- Size:
- 453 amino acids
- Molecular mass:
- 51034 Da
- Quaternary structure:
- No Data Available
Protein Expression for TUBD1 Gene
Post-translational modifications for TUBD1 Gene
Other Protein References for TUBD1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for TUBD1
- Invitrogen Antibodies for TUBD1
- Search GeneTex for Antibodies for TUBD1
-
Santa Cruz Biotechnology (SCBT) Antibodies for TUBD1
Protein Products
-
OriGene Purified Proteins for TUBD1
- Search Origene for MassSpec and Protein Over-expression Lysates for TUBD1
- Origene Custom Protein Services for TUBD1
- Search GeneTex for Proteins for TUBD1
Assay Products
No data available for DME Specific Peptides for TUBD1 Gene
Domains & Families for TUBD1 Gene
Gene Families for TUBD1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- FDA approved drug targets
- Predicted intracellular proteins
Protein Domains for TUBD1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for TUBD1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9UJT1- Family:
-
- Belongs to the tubulin family.
Function for TUBD1 Gene
Molecular function for TUBD1 Gene
- UniProtKB/Swiss-Prot Function:
- Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
Phenotypes From GWAS Catalog for TUBD1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA | -- |
| GO:0005200 | structural constituent of cytoskeleton | IEA | -- |
| GO:0005525 | GTP binding | IEA | -- |
Phenotypes for TUBD1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for TUBD1
-
CRISPR Products
-
OriGene CRISPR knockouts for TUBD1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TUBD1
- genomics-online: gRNA clones - Search results for 158 available TUBD1 gene related products
- Overview of 158 available TUBD1 gene related products
-
Recommended
- Applied Biological Materials CRISPR for TUBD1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TUBD1
- GenScript: Design CRISPR guide RNA sequences for TUBD1
miRNA for TUBD1 Gene
- miRTarBase miRNAs that target TUBD1
-
- hsa-mir-26b-5p (MIRT028800)
- hsa-mir-1276 (MIRT449868)
- hsa-mir-376a-2-5p (MIRT573334)
- hsa-mir-7150 (MIRT573335)
- hsa-mir-4451 (MIRT573336)
- hsa-mir-4650-3p (MIRT573337)
- hsa-mir-5681a (MIRT573338)
- hsa-mir-3529-5p (MIRT573339)
- hsa-mir-379-5p (MIRT573340)
- hsa-mir-96-5p (MIRT573341)
- hsa-mir-182-5p (MIRT573342)
- hsa-mir-1271-5p (MIRT573343)
- hsa-mir-2054 (MIRT614116)
- hsa-mir-190a-3p (MIRT614117)
- hsa-mir-380-3p (MIRT614118)
- hsa-mir-411-3p (MIRT614119)
- hsa-mir-379-3p (MIRT614120)
- hsa-mir-4495 (MIRT614121)
- hsa-mir-5011-5p (MIRT614122)
- hsa-mir-4789-3p (MIRT614123)
- hsa-mir-8485 (MIRT614124)
- hsa-mir-3941 (MIRT628731)
- hsa-mir-603 (MIRT628732)
- hsa-mir-362-3p (MIRT628733)
- hsa-mir-329-3p (MIRT628734)
- hsa-mir-6783-3p (MIRT665574)
- hsa-mir-1343-3p (MIRT665575)
- hsa-mir-23b-5p (MIRT665576)
- hsa-mir-23a-5p (MIRT665577)
- hsa-mir-4284 (MIRT665578)
- hsa-mir-6829-3p (MIRT665579)
- hsa-mir-6791-3p (MIRT665580)
- hsa-mir-2276-3p (MIRT665581)
- hsa-mir-4638-5p (MIRT665582)
- hsa-mir-1307-3p (MIRT665583)
- hsa-mir-1304-3p (MIRT665584)
- hsa-mir-6741-3p (MIRT665585)
- hsa-mir-1281 (MIRT665586)
- hsa-mir-6852-5p (MIRT665587)
- hsa-mir-939-3p (MIRT665588)
- hsa-mir-660-3p (MIRT665589)
- hsa-mir-4485-5p (MIRT665590)
- hsa-mir-6890-3p (MIRT665591)
- hsa-mir-598-3p (MIRT665592)
- hsa-mir-7151-3p (MIRT706821)
- hsa-mir-5095 (MIRT706822)
- hsa-mir-365b-5p (MIRT706823)
- hsa-mir-365a-5p (MIRT706824)
- hsa-mir-8052 (MIRT706825)
- hsa-mir-3199 (MIRT706826)
- hsa-mir-6720-3p (MIRT706827)
- hsa-mir-6778-3p (MIRT706828)
- hsa-mir-4258 (MIRT706829)
- hsa-mir-4740-3p (MIRT706830)
- hsa-mir-6715b-5p (MIRT706831)
- hsa-mir-4269 (MIRT706832)
- hsa-mir-4438 (MIRT706833)
- hsa-mir-620 (MIRT717935)
- hsa-mir-4531 (MIRT717937)
- hsa-mir-1270 (MIRT717938)
- hsa-mir-550a-3p (MIRT717939)
- hsa-mir-200c-5p (MIRT717940)
- hsa-mir-6879-3p (MIRT717941)
- hsa-mir-139-3p (MIRT717942)
- hsa-mir-4524a-3p (MIRT717943)
- hsa-mir-550b-3p (MIRT717944)
- hsa-mir-215-3p (MIRT717945)
- hsa-mir-6773-3p (MIRT717946)
- hsa-mir-3664-5p (MIRT717947)
- hsa-mir-514a-5p (MIRT717948)
- hsa-mir-4714-5p (MIRT717949)
- hsa-mir-122-5p (MIRT761358)
- hsa-mir-143-5p (MIRT762704)
- hsa-mir-3135b (MIRT764955)
- hsa-mir-3652 (MIRT766316)
- hsa-mir-4430 (MIRT768951)
- hsa-mir-4634 (MIRT770506)
- hsa-mir-504-3p (MIRT773078)
- hsa-mir-5693 (MIRT775046)
- hsa-mir-5698 (MIRT775171)
- hsa-mir-6499-3p (MIRT776401)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TUBD1
- Browse OriGene Inhibitory RNA Products For TUBD1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TUBD1
- genomics-online: shRNA clones - Search results for 158 available TUBD1 gene related products
- Overview of 158 available TUBD1 gene related products
-
Recommended
Clone Products
-
OriGene ORF clones in human for TUBD1
- RC230822L1V
- RC230822L2V
- RC231207L1V
- RC231207L2V
- RC231177L1V
- RC231177L2V
- RC230791L1V
- RC230791L2V
- RC231084L1V
- RC231084L2V
- RC220591L1V
- RC220591L2V
- RC230822
- RC230822L1
- RC230822L2
- RG230822
- RC231207
- RC231207L1
- RC231207L2
- RG231207
- RC231177
- RC231177L1
- RC231177L2
- RG231177
- RC230791
- RC230791L1
- RC230791L2
- RG230791
- RC231084
- RC231084L1
- RC231084L2
- RG231084
- RC220591
- RC220591L1
- RC220591L2
- RG220591
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for TUBD1
- VectorBuilder custom plasmid, inducible vectors for TUBD1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TUBD1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TUBD1
- genomics-online: cdna clones - Search results for 158 available TUBD1 gene related products
- Overview of 158 available TUBD1 gene related products
-
Recommended
- orf clones - Search results for 158 available TUBD1 gene related products
- Overview of 158 available TUBD1 gene related products
-
Recommended
- Applied Biological Materials Clones for TUBD1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TUBD1 Gene
Localization for TUBD1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TUBD1 Gene
- Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell projection, cilium. Note=Associated with centrioles. Both cytoplasmic and nuclear. In the elongating spermatid it is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head. {ECO:0000250 UniProtKB:Q9R1K7}.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| nucleus | 5 |
| cytosol | 5 |
| peroxisome | 1 |
- Cytosol (4)
- Nucleoplasm (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IBA,IEA | -- |
| GO:0005814 | centriole | TAS,IEA | -- |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for TUBD1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Sertoli-Sertoli Cell Junction Dynamics | ||
| 2 | PAK Pathway | ||
| 3 | G-Beta Gamma Signaling | ||
| 4 | ERK Signaling | ||
| 5 | Remodeling of Adherens Junctions | ||
Pathways by source for TUBD1 Gene
Interacting Proteins for TUBD1 Gene
GPS-Prot Interaction Network for TUBD1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000226 | microtubule cytoskeleton organization | IBA | -- |
| GO:0000278 | mitotic cell cycle | IBA | -- |
| GO:0007010 | cytoskeleton organization | IEA | -- |
| GO:0007017 | microtubule-based process | IEA | -- |
| GO:0007275 | multicellular organism development | IEA | -- |
Drugs & Compounds for TUBD1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Vinblastine | Approved | Pharma | Target, adduct | 439 | ||
| Taxol | Approved August 1997 | Pharma | Agonist | Promotes assembly and inhibits disassembly of microtubules | 0 | |
| Nocodazole | Experimental | Pharma | Tubulin production inhibitor,anti-neoplastic agent, Microtubule inhibitor | 0 | ||
| MPC 6827 hydrochloride | Pharma | Potent microtubule inhibitor, Inhibitor of microtubule polymerization; antimitotic and antitumor | 0 | |||
| Vinblastine sulfate | Pharma | Anti-mitotic agent, Disrupts microtubules | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| Noscapine hydrochloride |
|
912-60-7 |
|
|
(5) Tocris Compounds for TUBD1 Gene
| Compound | Action | Cas Number |
|---|---|---|
| MPC 6827 hydrochloride | Inhibitor of microtubule polymerization; antimitotic and antitumor | 917369-31-4 |
| Nocodazole | Microtubule inhibitor | 31430-18-9 |
| Noscapine hydrochloride | Tubulin inhibitor; induces apoptosis | 912-60-7 |
| Taxol | Promotes assembly and inhibits disassembly of microtubules | 33069-62-4 |
| Vinblastine sulfate | Disrupts microtubules | 143-67-9 |
Transcripts for TUBD1 Gene
mRNA/cDNA for TUBD1 Gene
- (83) Selected AceView cDNA sequences:
- (11) Additional mRNA sequences :
- (15) REFSEQ mRNAs :
- (16) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000325752 2490 bps (uc002ixw.3)
- ENST00000340993 1769 bps (uc002ixx.3)
- ENST00000346141 1490 bps (uc010ddi.3)
- ENST00000376094 1154 bps (uc060ieh.1)
- ENST00000394239 1680 bps (uc010wok.3)
Unigene Clusters for TUBD1 Gene
- Tubulin, delta 1:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for TUBD1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TUBD1
- genomics-online: gRNA clones - Search results for 158 available TUBD1 gene related products
- Overview of 158 available TUBD1 gene related products
-
Recommended
- Applied Biological Materials CRISPR for TUBD1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TUBD1
- GenScript: Design CRISPR guide RNA sequences for TUBD1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TUBD1
- Browse OriGene Inhibitory RNA Products For TUBD1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TUBD1
- genomics-online: shRNA clones - Search results for 158 available TUBD1 gene related products
- Overview of 158 available TUBD1 gene related products
-
Recommended
Clone Products
-
OriGene ORF clones in human for TUBD1
- RC230822L1V
- RC230822L2V
- RC231207L1V
- RC231207L2V
- RC231177L1V
- RC231177L2V
- RC230791L1V
- RC230791L2V
- RC231084L1V
- RC231084L2V
- RC220591L1V
- RC220591L2V
- RC230822
- RC230822L1
- RC230822L2
- RG230822
- RC231207
- RC231207L1
- RC231207L2
- RG231207
- RC231177
- RC231177L1
- RC231177L2
- RG231177
- RC230791
- RC230791L1
- RC230791L2
- RG230791
- RC231084
- RC231084L1
- RC231084L2
- RG231084
- RC220591
- RC220591L1
- RC220591L2
- RG220591
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for TUBD1
- VectorBuilder custom plasmid, inducible vectors for TUBD1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TUBD1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TUBD1
- genomics-online: cdna clones - Search results for 158 available TUBD1 gene related products
- Overview of 158 available TUBD1 gene related products
-
Recommended
- orf clones - Search results for 158 available TUBD1 gene related products
- Overview of 158 available TUBD1 gene related products
-
Recommended
- Applied Biological Materials Clones for TUBD1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP8: | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP13: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP14: | - | - | - | - | - | - | - | - | - | - |
Expression for TUBD1 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TUBD1 Gene
NURSA nuclear receptor signaling pathways regulating expression of TUBD1 Gene:
TUBD1SOURCE GeneReport for Unigene cluster for TUBD1 Gene:
Hs.463638Evidence on tissue expression from TISSUES for TUBD1 Gene
- Eye(4.1)
- Stomach(4.1)
Primer Products
-
OriGene qPCR primer pairs and template standards for TUBD1
-
OriGene qPCR primer pairs for TUBD1
- genomics-online: primer clones - Search results for 158 available TUBD1 gene related products
- Overview of 158 available TUBD1 gene related products
-
Recommended
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TUBD1 Gene
Orthologs for TUBD1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | TUBD1 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | TUBD1 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | TUBD1 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Tubd1 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Tubd1 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | TUBD1 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | TUBD1 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | TUBD1 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | TUBD1 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | tubd1 33 |
|
||
| Str.12654 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | tubd1-A-prov 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | tubd1 34 33 |
|
OneToOne | |
| worm (Caenorhabditis elegans) |
Secernentea | tbg-1 34 |
|
OneToOne | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | TUB4 34 |
|
OneToMany |
- Species where no ortholog for TUBD1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for TUBD1 Gene
- ENSEMBL:
- Gene Tree for TUBD1 (if available)
- TreeFam:
- Gene Tree for TUBD1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TUBD1: view image
Paralogs for TUBD1 Gene
Paralogs for TUBD1 Gene
(5) SIMAP similar genes for TUBD1 Gene using alignment to 5 proteins:
- TBD_HUMAN
- K7EKE2_HUMAN
- K7EMW6_HUMAN
- K7EPQ0_HUMAN
- K7EQN9_HUMAN
Variants for TUBD1 Gene
| SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000021445 | -- | 59,891,985(-) | A/T | intron_variant | |
| rs1000207163 | -- | 59,869,174(-) | G/A/C | intron_variant | |
| rs1000312990 | -- | 59,862,850(-) | G/A/C | intron_variant | |
| rs1000333130 | -- | 59,874,639(-) | A/C/G | coding_sequence_variant, intron_variant, synonymous_variant | |
| rs1000336935 | -- | 59,893,558(-) | G/A | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2716085 | CNV | deletion | 23290073 |
| esv3554613 | CNV | deletion | 23714750 |
| esv3640914 | CNV | gain | 21293372 |
| nsv1116228 | CNV | deletion | 24896259 |
Residual Variation Intolerance Score:
32.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
13.32;
95.35% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TUBD1 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TUBD1 Gene
Disorders for TUBD1 Gene
Additional Disease Information for TUBD1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for TUBD1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TUBD1 Gene
Publications for TUBD1 Gene
- Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function. (PMID: 10620804) Chang P … Stearns T (Nature cell biology 2000) 2 3 4 22 58
- Delta-tubulin is a component of intercellular bridges and both the early and mature perinuclear rings during spermatogenesis. (PMID: 15081367) Kato A … Todokoro K (Developmental biology 2004) 3 4 22 58
- Centrosome-related genes, genetic variation, and risk of breast cancer. (PMID: 20508983) Olson JE … Couch FJ (Breast cancer research and treatment 2011) 3 44 58
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 44 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
Products for TUBD1 Gene
- Browse R&D Systems for Antibodies
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- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
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- Browse Immunoprecipitation Assays
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- Browse OriGene Antibodies
- Custom Antibody Services
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- Custom Assay Services
- OriGene Purified Proteins for TUBD1
- Search Origene for MassSpec and Protein Over-expression Lysates for TUBD1
- Origene Custom Protein Services for TUBD1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TUBD1
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- OriGene qPCR primer pairs and template standards for TUBD1
- OriGene qPCR primer pairs for TUBD1
- OriGene CRISPR knockouts for TUBD1
- OriGene ORF clones in human for TUBD1
- RC230822L1V
- RC230822L2V
- RC231207L1V
- RC231207L2V
- RC231177L1V
- RC231177L2V
- RC230791L1V
- RC230791L2V
- RC231084L1V
- RC231084L2V
- RC220591L1V
- RC220591L2V
- RC230822
- RC230822L1
- RC230822L2
- RG230822
- RC231207
- RC231207L1
- RC231207L2
- RG231207
- RC231177
- RC231177L1
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- RG231177
- RC230791
- RC230791L1
- RC230791L2
- RG230791
- RC231084
- RC231084L1
- RC231084L2
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- RC220591
- RC220591L1
- RC220591L2
- RG220591
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping of latest version cDNA ORF clones for TUBD1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for TUBD1
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- GenScript Custom overexpressing Cell Line Services for TUBD1
- GenScript: Design CRISPR guide RNA sequences for TUBD1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
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- Sino Biological Human cDNA Clone for TUBD1
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- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for TUBD1
- Novus Biologicals proteins and lysates for TUBD1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
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- VectorBuilder custom plasmid, inducible vectors for TUBD1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TUBD1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 36 available TUBD1 Antibodies ranked by validation data
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- antibodies-online: Search results for 11 available TUBD1 Proteins ranked by validation data
- Compare Top TUBD1 Proteins
- Search GeneTex for Antibodies for TUBD1
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- Santa Cruz Biotechnology (SCBT) Antibodies for TUBD1
- Search Santa Cruz Biotechnology (SCBT) for TUBD1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for TUBD1
- genomics-online: cdna clones - Search results for 158 available TUBD1 gene related products
- Overview of 158 available TUBD1 gene related products
- Recommended
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- Overview of 158 available TUBD1 gene related products
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- Overview of 158 available TUBD1 gene related products
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- Overview of 158 available TUBD1 gene related products
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Sources for TUBD1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70)