Aliases for TUBD1 Gene
External Ids for TUBD1 Gene
Previous GeneCards Identifiers for TUBD1 Gene
GeneCards Summary for TUBD1 Gene
TUBD1 (Tubulin Delta 1) is a Protein Coding gene. Diseases associated with TUBD1 include Seckel Syndrome 7 and Orofaciodigital Syndrome Ix. Among its related pathways are Remodeling of Adherens Junctions and G-Beta Gamma Signaling. Gene Ontology (GO) annotations related to this gene include GTP binding and structural constituent of cytoskeleton. An important paralog of this gene is TUBB8.
UniProtKB/Swiss-Prot Summary for TUBD1 Gene
Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
Microtubules are cylindrical tubes of 20-25 nm in diameter. They are composed of protofilaments which are in turn composed of alpha- and beta-tubulin polymers. Each microtubule is polarized; at one end alpha-subunits are exposed (-) and at the other, beta-subunits are exposed (+).