Aliases for TUBA1C Gene
External Ids for TUBA1C Gene
Previous HGNC Symbols for TUBA1C Gene
Previous GeneCards Identifiers for TUBA1C Gene
GeneCards Summary for TUBA1C Gene
TUBA1C (Tubulin Alpha 1c) is a Protein Coding gene. Diseases associated with TUBA1C include Osteoblastoma. Among its related pathways are Gap junction and Chaperonin-mediated protein folding. Gene Ontology (GO) annotations related to this gene include GTP binding and structural molecule activity. An important paralog of this gene is TUBA1B.
UniProtKB/Swiss-Prot Summary for TUBA1C Gene
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Microtubules are cylindrical tubes of 20-25 nm in diameter. They are composed of protofilaments which are in turn composed of alpha- and beta-tubulin polymers. Each microtubule is polarized; at one end alpha-subunits are exposed (-) and at the other, beta-subunits are exposed (+).