Aliases for TUB Gene
Aliases for TUB Gene
External Ids for TUB Gene
- HGNC: 12406
- Entrez Gene: 7275
- Ensembl: ENSG00000166402
- OMIM: 601197
- UniProtKB: P50607
Previous GeneCards Identifiers for TUB Gene
- GC11P008828
- GC11P008520
- GC11P007999
- GC11P008024
- GC11P008016
- GC11P007727
Summaries for TUB Gene
-
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for TUB Gene
TUB (Tubby Bipartite Transcription Factor) is a Protein Coding gene. Diseases associated with TUB include Retinal Dystrophy And Obesity and Retinitis Pigmentosa. Among its related pathways are Presynaptic function of Kainate receptors and Transcription_Transcription factor Tubby signaling pathways. Gene Ontology (GO) annotations related to this gene include G-protein coupled photoreceptor activity. An important paralog of this gene is TULP1.
UniProtKB/Swiss-Prot for TUB Gene
-
Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight (By similarity). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages.
Additional gene information for TUB Gene
- Monarch Initiative
- Search for TUB at DataMed
- Search for TUB at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TUB Gene
Genomics for TUB Gene
GeneHancer (GH) Regulatory Elements for TUB Gene
Promoters and enhancers for TUB Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around TUB on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the TUB gene promoter:
-
- Zic1
- NCX
- Spz1
- S8
- Ik-2
- HEN1
- AP-1
- CUTL1
- c-Fos
- c-Jun
Regulatory Element Products
Genomic Locations for TUB Gene
Genomic Locations for TUB Gene
- chr11:8,019,180-8,106,241
- (GRCh38/hg38)
- Size:
- 87,062 bases
- Orientation:
- Plus strand
- chr11:8,040,791-8,127,659
- (GRCh37/hg19)
- Size:
- 86,869 bases
- Orientation:
- Plus strand
Genomic View for TUB Gene
Genes around TUB on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11p15.4 by Entrez Gene
- 11p15.4 by HGNC
- 11p15.4 by Ensembl
TUB Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TUB Gene
Proteins for TUB Gene
-
Protein details for TUB Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P50607-TUB_HUMAN
- Recommended name:
- Tubby protein homolog
- Protein Accession:
- P50607
- D3DQU4
- O00293
- Q6B007
Protein attributes for TUB Gene
- Size:
- 506 amino acids
- Molecular mass:
- 55651 Da
- Quaternary structure:
-
- Interacts with GNAQ. Interacts with TULP1.
Protein Expression for TUB Gene
Post-translational modifications for TUB Gene
Other Protein References for TUB Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for TUB
-
Abcam antibodies for TUB
- Invitrogen Antibodies for TUB
- GeneTex TUB Antibody for TUB
-
Santa Cruz Biotechnology (SCBT) Antibodies for TUB
- Sino Biological Antibodies for TUB
Protein Products
-
OriGene Purified Proteins for TUB
- Search Origene for MassSpec and Protein Over-expression Lysates for TUB
- Origene Custom Protein Services for TUB
- Novus Biologicals proteins for TUB
- Search GeneTex for Proteins for TUB
-
Abcam proteins for TUB
No data available for DME Specific Peptides for TUB Gene
Domains & Families for TUB Gene
Gene Families for TUB Gene
- Human Protein Atlas (HPA):
-
- Disease related genes
- Predicted intracellular proteins
Protein Domains for TUB Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for TUB Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P50607- Family:
-
- Belongs to the TUB family.
Function for TUB Gene
Molecular function for TUB Gene
- UniProtKB/Swiss-Prot Function:
- Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight (By similarity). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages.
- GENATLAS Biochemistry:
- tubby gene homolog of mouse (Tub) of mild naturity onset obesity,progressive retinal and cochlear degeneration,expressed in cochlea,retina,brain,testis
Phenotypes From GWAS Catalog for TUB Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0035091 | phosphatidylinositol binding | IBA | -- |
| GO:0044877 | protein-containing complex binding | IDA | 20889716 |
Phenotypes for TUB Gene
- MGI mutant phenotypes for TUB:
-
inferred from 3 alleles
- cardiovascular system phenotype
- pigmentation phenotype
- vision/eye phenotype
- homeostasis/metabolism phenotype
- nervous system phenotype
- behavior/neurological phenotype
- endocrine/exocrine gland phenotype
- cellular phenotype
- liver/biliary system phenotype
- hearing/vestibular/ear phenotype
- adipose tissue phenotype
- immune system phenotype
- growth/size/body region phenotype
- GenomeRNAi human phenotypes for TUB:
Animal Models for TUB Gene
- MGI Knock Outs for TUB:
-
- Tub Tub<tm1Rok>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for TUB
-
CRISPR Products
-
OriGene CRISPR knockouts for TUB
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TUB
- genomics-online: gRNA clones - Search results for 81 available TUB gene related products
- Overview of 81 available TUB gene related products
- Applied Biological Materials CRISPR for TUB
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TUB
- GenScript: Design CRISPR guide RNA sequences for TUB
miRNA for TUB Gene
- miRTarBase miRNAs that target TUB
-
- hsa-mir-128-3p (MIRT021923)
- hsa-mir-124-3p (MIRT022311)
- hsa-mir-221-3p (MIRT024147)
- hsa-mir-940 (MIRT036622)
- hsa-mir-744-5p (MIRT037636)
- hsa-mir-320a (MIRT044577)
- hsa-mir-181c-5p (MIRT047219)
- hsa-mir-653-5p (MIRT544946)
- hsa-mir-26b-5p (MIRT544947)
- hsa-mir-4465 (MIRT544948)
- hsa-mir-26a-5p (MIRT544949)
- hsa-mir-1297 (MIRT544950)
- hsa-mir-4775 (MIRT544951)
- hsa-mir-6867-5p (MIRT544952)
- hsa-mir-3177-5p (MIRT544953)
- hsa-mir-511-3p (MIRT544954)
- hsa-mir-374c-3p (MIRT544955)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for TUB
- Browse OriGene Inhibitory RNA Products For TUB
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TUB
- genomics-online: shRNA clones - Search results for 81 available TUB gene related products
- Overview of 81 available TUB gene related products
Clone Products
- Sino Biological Human cDNA Clone for TUB
- VectorBuilder custom plasmid, inducible vectors for TUB
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TUB
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TUB
- Applied Biological Materials Clones for TUB
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for TUB
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for TUB Gene
Localization for TUB Gene
Subcellular locations from UniProtKB/Swiss-Prot for TUB Gene
- Cytoplasm. Nucleus. Secreted. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Binds phospholipid and is anchored to the plasma membrane through binding phosphatidylinositol 4,5-bisphosphate. Is released upon activation of phospholipase C. Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha. Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity). {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| extracellular | 4 |
| cytosol | 4 |
| plasma membrane | 3 |
| cytoskeleton | 3 |
| mitochondrion | 2 |
- Centrosome (2)
- Microtubule organizing center (2)
- Nucleoli (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
| GO:0005634 | nucleus | TAS,IEA | -- |
| GO:0005737 | cytoplasm | TAS | 11000483 |
| GO:0005829 | cytosol | IEA | -- |
| GO:0005886 | plasma membrane | IEA | -- |
Pathways & Interactions for TUB Gene
Pathways by source for TUB Gene
1 GeneGo (Thomson Reuters) pathway for TUB Gene
1 Qiagen pathway for TUB Gene
Interacting Proteins for TUB Gene
GPS-Prot Interaction Network for TUB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006909 | phagocytosis | IEA | -- |
| GO:0006910 | phagocytosis, recognition | IEA | -- |
| GO:0007605 | sensory perception of sound | IEA | -- |
| GO:0009725 | response to hormone | IEA | -- |
| GO:0045494 | photoreceptor cell maintenance | IEA | -- |
No data available for SIGNOR curated interactions for TUB Gene
Drugs & Compounds for TUB Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| (1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate)] | Experimental | Pharma | Target | 0 |
Transcripts for TUB Gene
mRNA/cDNA for TUB Gene
- (4) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (72) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000534099 1759 bps (uc010rbk.3)
- ENST00000305253 6420 bps (uc001mfy.4)
- ENST00000299506 2019 bps (uc001mga.4)
CRISPR Products
-
OriGene CRISPR knockouts for TUB
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TUB
- genomics-online: gRNA clones - Search results for 81 available TUB gene related products
- Overview of 81 available TUB gene related products
- Applied Biological Materials CRISPR for TUB
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TUB
- GenScript: Design CRISPR guide RNA sequences for TUB
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for TUB
- Browse OriGene Inhibitory RNA Products For TUB
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TUB
- genomics-online: shRNA clones - Search results for 81 available TUB gene related products
- Overview of 81 available TUB gene related products
Clone Products
- Sino Biological Human cDNA Clone for TUB
- VectorBuilder custom plasmid, inducible vectors for TUB
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TUB
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TUB
- Applied Biological Materials Clones for TUB
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||||||||
| SP4: |
Expression for TUB Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Eye (Sensory Organs)
- Mature Rod Cells Outer Nuclear Layer
-
Neurons
- Mature Rod Cells Outer Nuclear Layer
-
Brain (Nervous System)
- Mature Endothelial Cells Blood Brain Barrier
-
Endothelium (Cardiovascular System)
- Mature Endothelial Cells Blood Brain Barrier
-
Kidney (Urinary System)
This gene is overexpressed in Fetal Brain (31.7) and Retina (31.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TUB Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of TUB Gene:
TUBSOURCE GeneReport for Unigene cluster for TUB Gene:
Hs.568986Evidence on tissue expression from TISSUES for TUB Gene
- Nervous system(4.7)
- Skin(2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for TUB Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- immune
- integumentary
- nervous
- reproductive
- respiratory
- skeletal muscle
- skeleton
Regions:
Head and neck:
- brain
- cerebellum
- cranial nerve
- ear
- eye
- eyelid
- face
- head
- middle ear
- nose
- outer ear
- skull
Pelvis:
- penis
- testicle
General:
- blood
- blood vessel
- peripheral nervous system
- red blood cell
- skin
Primer Products
-
OriGene qPCR primer pairs and template standards for TUB
-
OriGene qPCR primer pairs for TUB
- genomics-online: primer clones - Search results for 81 available TUB gene related products
- Overview of 81 available TUB gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TUB Gene
Orthologs for TUB Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | TUB 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | TUB 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Tub 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Tub 33 |
|
||
| cow (Bos Taurus) |
Mammalia | TUB 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | TUB 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | TUB 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | TUB 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | TUB 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | tub 33 |
|
||
| Str.12141 33 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | TUB 34 |
|
OneToOne | |
| tub 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | Tulp 35 |
|
|
|
| king-tubby 34 |
|
OneToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | tub-1 34 35 33 |
|
OneToMany | |
| Alicante grape (Vitis vinifera) |
eudicotyledons | Vvi.6835 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os03g0351400 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany | |
| Cin.13886 33 |
|
||||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.13886 33 |
|
- Species where no ortholog for TUB was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for TUB Gene
- ENSEMBL:
- Gene Tree for TUB (if available)
- TreeFam:
- Gene Tree for TUB (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TUB: view image
Paralogs for TUB Gene
Variants for TUB Gene
| SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs727502810 | pathogenic, Retinal dystrophy and obesity | 8,100,575(+) | GAGAGAG/GAGAG | coding_sequence_variant, frameshift | |
| rs1000006631 | -- | 8,092,818(+) | G/A | intron_variant | |
| rs1000036415 | -- | 8,099,076(+) | G/A | intron_variant | |
| rs1000060116 | -- | 8,086,407(+) | G/A | intron_variant | |
| rs1000066580 | -- | 8,068,617(+) | C/T | genic_upstream_transcript_variant, intron_variant |
Residual Variation Intolerance Score:
16.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.06;
50.62% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TUB Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TUB Gene
Disorders for TUB Gene
(5) MalaCards diseases for TUB Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| retinal dystrophy and obesity |
|
|
| retinitis pigmentosa |
|
|
| retinitis pigmentosa 14 |
|
|
| deafness, autosomal recessive 26 |
|
|
| signet ring cell adenocarcinoma |
|
|
Search TUB in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
TUB_HUMAN- Retinal dystrophy and obesity (RDOB) [MIM:616188]: A disease characterized by obesity, night blindness, decreased visual acuity, and electrophysiological features of a rod cone dystrophy. {ECO:0000269 PubMed:24375934}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for TUB
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for TUB Gene
Publications for TUB Gene
- Molecular characterization of TUB, TULP1, and TULP2, members of the novel tubby gene family and their possible relation to ocular diseases. (PMID: 9096357) North MA … Nishina PM (Proceedings of the National Academy of Sciences of the United States of America 1997) 3 4 22 58
- Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family. (PMID: 8612280) Kleyn PW … Moore KJ (Cell 1996) 2 3 4 58
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 44 58
- Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. (PMID: 20080650) Xu J … Isaacs WB (Proceedings of the National Academy of Sciences of the United States of America 2010) 3 44 58
- Identification of tubby and tubby-like protein 1 as eat-me signals by phage display. (PMID: 19837063) Caberoy NB … Li W (Experimental cell research 2010) 3 4 58
Products for TUB Gene
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- Novus Biologicals
- Novus Biologicals Tissue Microarrays
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- Find your target
- Browse Primary Antibodies
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- Cyagen custom Knockout/knockin (KOKI) mouse models for TUB
- VectorBuilder custom plasmid, inducible vectors for TUB
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TUB
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 10 available TUB Antibodies ranked by validation data
- Compare Top TUB Antibodies
- antibodies-online: Search results for available TUB related products ranked by validation data
- antibodies-online: Search results for 5 available TUB Proteins ranked by validation data
- Compare Top TUB Proteins
- GeneTex TUB Antibody for TUB
- Search GeneTex for Proteins for TUB
- Santa Cruz Biotechnology (SCBT) Antibodies for TUB
- Search Santa Cruz Biotechnology (SCBT) for TUB siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for TUB
- Horizon Cell Lines for TUB
- genomics-online: cdna clones - Search results for 81 available TUB gene related products
- Overview of 81 available TUB gene related products
- orf clones - Search results for 81 available TUB gene related products
- Overview of 81 available TUB gene related products
- genomics-online: gRNA clones - Search results for 81 available TUB gene related products
- Overview of 81 available TUB gene related products
- genomics-online: primer clones - Search results for 81 available TUB gene related products
- Overview of 81 available TUB gene related products
- genomics-online: shRNA clones - Search results for 81 available TUB gene related products
- Overview of 81 available TUB gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TUB
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TUB
- GeneCopoeia miRNA 3'UTR Target clone products for TUB
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TUB
Sources for TUB Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt