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This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause heredi... See more...
Aliases for TTPA Gene
Aliases for TTPA Gene
External Ids for TTPA Gene
- HGNC: 12404
- Entrez Gene: 7274
- Ensembl: ENSG00000137561
- OMIM: 600415
- UniProtKB: P49638
Previous HGNC Symbols for TTPA Gene
- AVED
Previous GeneCards Identifiers for TTPA Gene
- GC08M063337
- GC08M063913
- GC08M063695
- GC08M064022
- GC08M064134
- GC08M059459
- GC08M063961
Summaries for TTPA Gene
-
This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa. [provided by RefSeq, Nov 2009]
GeneCards Summary for TTPA Gene
TTPA (Alpha Tocopherol Transfer Protein) is a Protein Coding gene. Diseases associated with TTPA include Vitamin E, Familial Isolated Deficiency Of and Ataxia With Vitamin E Deficiency. Gene Ontology (GO) annotations related to this gene include transporter activity and phosphatidylinositol-3,4-bisphosphate binding. An important paralog of this gene is SEC14L3.
UniProtKB/Swiss-Prot Summary for TTPA Gene
-
Binds alpha-tocopherol, enhances its transfer between separate membranes, and stimulates its release from liver cells (PubMed:7887897). Binds both phosphatidylinol 3,4-bisphosphate and phosphatidylinol 4,5-bisphosphate; the resulting conformation change is important for the release of the bound alpha-tocopherol (By similarity).
Additional gene information for TTPA Gene
- HGNC(12404)
- Entrez Gene(7274)
- Ensembl(ENSG00000137561)
- OMIM(600415)
- UniProtKB(P49638)
- Open Targets Platform(ENSG00000137561)
- Monarch Initiative
- Search for TTPA at DataMed
- Search for TTPA at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TTPA Gene
Genomics for TTPA Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TTPA Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TTPA on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TTPA
- Top Transcription factor binding sites by QIAGEN in the TTPA gene promoter:
-
- aMEF-2
- Cart-1
- FAC1
- FOXD1
- Lhx3a
- LHX3b
- MEF-2A
- PPAR-alpha
- RSRFC4
Genomic Locations for TTPA Gene
Genomic Locations for TTPA Gene
- chr8:63,048,553-63,086,523
- (GRCh38/hg38)
- Size:
- 37,971 bases
- Orientation:
- Minus strand
- chr8:63,961,112-63,998,612
- (GRCh37/hg19)
- Size:
- 37,501 bases
- Orientation:
- Minus strand
Genomic View for TTPA Gene
Genes around TTPA on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8q12.3 by HGNC
- 8q12.3 by Entrez Gene
- 8q12.3 by Ensembl
TTPA Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TTPA Gene
Proteins for TTPA Gene
-
Protein details for TTPA Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P49638-TTPA_HUMAN
- Recommended name:
- Alpha-tocopherol transfer protein
- Protein Accession:
- P49638
- Q71V64
Protein attributes for TTPA Gene
- Size:
- 278 amino acids
- Molecular mass:
- 31750 Da
- Quaternary structure:
-
- Monomer and homotetramer. Phosphatidylinol 4,5-bisphosphate binding induces the formation of homotetramers. Phosphatidylinol 3,4-bisphosphate is less efficient in inducing tetramerization (By similarity).
Protein Expression for TTPA Gene
Post-translational modifications for TTPA Gene
Other Protein References for TTPA Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Protein Products
-
OriGene Purified Proteins for TTPA
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- Origene Custom Protein Services for TTPA
- Novus Biologicals proteins for TTPA
- antibodies-online: Show 7 available TTPA Proteins ranked by validation data
- Compare Top TTPA Proteins
-
Quality Products:
Assay Products
- antibodies-online: Show 17 available TTPA Elisa Kits ranked by validation data
- Compare Top TTPA Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for TTPA Gene
Domains & Families for TTPA Gene
Gene Families for TTPA Gene
- Human Protein Atlas (HPA):
-
- Disease related genes
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for TTPA Gene
- InterPro:
- Blocks:
-
- Cellular retinaldehyde-binding (CRAL)/Triple function domain (TRIO)
- Cellular retinaldehyde-binding protein signature
- Cellular retinaldehyde-binding/triple function, N-terminal
- ProtoNet:
Suggested Antigen Peptide Sequences for TTPA Gene
- GenScript: Design optimal peptide antigens:
-
- Alpha-tocopherol transfer protein (TTPA_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TTPA Gene
Function for TTPA Gene
Molecular function for TTPA Gene
- UniProtKB/Swiss-Prot Function:
- Binds alpha-tocopherol, enhances its transfer between separate membranes, and stimulates its release from liver cells (PubMed:7887897). Binds both phosphatidylinol 3,4-bisphosphate and phosphatidylinol 4,5-bisphosphate; the resulting conformation change is important for the release of the bound alpha-tocopherol (By similarity).
- GENATLAS Biochemistry:
- alpha-tocopherol transfer protein
Phenotypes From GWAS Catalog for TTPA Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding | IEA,ISS | -- |
| GO:0008289 | lipid binding | IEA | -- |
| GO:0008431 | vitamin E binding | TAS,ISS | -- |
| GO:0019842 | vitamin binding | IEA | -- |
Phenotypes for TTPA Gene
- MGI mutant phenotypes for TTPA:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for TTPA:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TTPA - Select products 50% OFF >
- * TTPA CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TTPA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TTPA
-
Santa Cruz Biotechnology (SCBT) CRISPR for TTPA
miRNA for TTPA Gene
- miRTarBase miRNAs that target TTPA
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TTPA
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Clone Products
- Applied Biological Materials (abm): Clones for TTPA - Select products 50% OFF >
- * TTPA as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TTPA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TTPA
Cell Line Products
-
Horizon Cell Lines for TTPA
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for TTPA Gene
Localization for TTPA Gene
Subcellular locations from UniProtKB/Swiss-Prot for TTPA Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| endosome | 4 |
| nucleus | 3 |
| plasma membrane | 2 |
| extracellular | 2 |
| cytoskeleton | 2 |
| mitochondrion | 2 |
| endoplasmic reticulum | 2 |
| peroxisome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005623 | cell | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005770 | late endosome | IEA,IBA | 21873635 |
| GO:0005829 | cytosol | IEA,TAS | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for TTPA Gene
Pathways & Interactions for TTPA Gene
Interacting Proteins for TTPA Gene
Selected Interacting proteins:
P49638-TTPA_HUMAN
ENSP00000260116
for TTPA Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for TTPA
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001890 | placenta development | IEA | -- |
| GO:0001892 | embryonic placenta development | IEA | -- |
| GO:0006629 | lipid metabolic process | TAS | 7887897 |
| GO:0007584 | response to nutrient | IEA | -- |
| GO:0009268 | response to pH | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for TTPA Gene
Drugs & Compounds for TTPA Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Vitamin E | Approved, Vet_approved | Nutra | Carrier | 526,534 | ||
| alpha-Tocopherol acetate | Approved, Vet_approved | Nutra | Carrier, Transporter, substrate | 0 | ||
| Tocopherol | Approved, Investigational | Pharma | Transporter, substrate | 9,535 | ||
| Tocofersolan | Approved | Pharma | Transporter, substrate | 0 | ||
| alpha-Tocopherol succinate | Approved, Vet_approved | Nutra | Carrier | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for TTPA Gene
mRNA/cDNA for TTPA Gene
- 1 REFSEQ mRNAs :
- 4 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000260116 2633 nts (view in UCSC)
- ENST00000521138 283 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TTPA - Select products 50% OFF >
- * TTPA CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TTPA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TTPA
-
Santa Cruz Biotechnology (SCBT) CRISPR for TTPA
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TTPA
- Browse OriGene Inhibitory RNA Products For TTPA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TTPA
Clone Products
- Applied Biological Materials (abm): Clones for TTPA - Select products 50% OFF >
- * TTPA as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TTPA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TTPA
Relevant External Links for TTPA Gene
- GeneLoc Exon Structure for
- TTPA
Expression for TTPA Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Pancreas (Endocrine System)
- Duct Cells Pancreatic Ducts
-
Epithelial Cells
- Duct Cells Pancreatic Ducts
-
Blood (Hematopoietic System)
- Hematopoietic Stem Cells Hematopoietic Bone Marrow
-
Brain (Nervous System)
- Protoplasmic Astrocyte Cells Neocortex
-
Glial Cells
- Protoplasmic Astrocyte Cells Neocortex
-
Liver (Hepatobiliary System)
mRNA differential expression in normal tissues according to GTEx for TTPA Gene
This gene is overexpressed in Liver (x35.8).
This gene is overexpressed in Gallbladder (43.8), Liver (16.6), and Fetal Liver (8.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TTPA Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TTPA
SOURCE GeneReport for Unigene cluster for TTPA Gene:
Hs.69049Evidence on tissue expression from TISSUES for TTPA Gene
- Liver(4.7)
- Kidney(4.4)
- Blood(2.6)
- Nervous system(2.4)
Phenotype-based relationships between genes and organs from Gene ORGANizer for TTPA Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- immune
- integumentary
- nervous
- respiratory
- skeletal muscle
- skeleton
Regions:
Head and neck:
- brain
- cranial nerve
- ear
- eye
- eyelid
- face
- head
Thorax:
- heart
- lung
- rib
- rib cage
Abdomen:
- duodenum
- intestine
- liver
- pancreas
- small intestine
Pelvis:
- pelvis
Limb:
- foot
- lower limb
General:
- blood vessel
- peripheral nerve
- peripheral nervous system
- skin
- spinal column
- spinal cord
- vertebrae
Primer Products
-
OriGene qPCR primer pairs for TTPA
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt for TTPA Gene
Orthologs for TTPA Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TTPA 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | TTPA 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | TTPA 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Ttpa 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Ttpa 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | TTPA 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | TTPA 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | TTPA 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | TTPA 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | ttpa 30 31 |
|
OneToOne | |
| wufd44e05 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG10237 32 |
|
|
|
| pinta 31 |
|
ManyToMany | |||
| CG33966 31 |
|
ManyToMany | |||
| CG3823 31 |
|
ManyToMany | |||
| Cralbp 31 |
|
ManyToMany | |||
| CG33514 31 |
|
ManyToMany | |||
| CG33965 31 |
|
ManyToMany | |||
| CG30339 31 |
|
ManyToMany | |||
| CG10657 31 |
|
ManyToMany | |||
| CG10300 31 |
|
ManyToMany | |||
| CG2663 31 |
|
ManyToMany | |||
| CG31636 31 |
|
ManyToMany | |||
| CG12926 31 |
|
ManyToMany | |||
| CG3091 31 |
|
ManyToMany | |||
| CG10301 31 |
|
ManyToMany | |||
| CG1902 31 |
|
ManyToMany | |||
| CG3191 31 |
|
ManyToMany | |||
| CG11550 31 |
|
ManyToMany | |||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
ManyToMany |
- Species where no ortholog for TTPA was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for TTPA Gene
- ENSEMBL:
- Gene Tree for TTPA (if available)
- TreeFam:
- Gene Tree for TTPA (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TTPA: view image
Paralogs for TTPA Gene
Variants for TTPA Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TTPA Gene
| SNP ID | Clinical significance and condition | Chr 08 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 721391 | Likely Benign: not provided | 63,073,008(-) | G/A | SYNONYMOUS_VARIANT | |
| 724632 | Conflicting Interpretations: Familial isolated deficiency of vitamin E; not provided | 63,085,986(-) | C/A | SYNONYMOUS_VARIANT | |
| 727159 | Likely Benign: not provided | 63,072,938(-) | T/C | MISSENSE_VARIANT | |
| 729056 | Benign: not provided | 63,085,875(-) | G/A | SYNONYMOUS_VARIANT | |
| 752168 | Benign: not provided | 63,065,985(-) | G/T | SYNONYMOUS_VARIANT |
Residual Variation Intolerance Score:
62.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.87;
18.23% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TTPA Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TTPA Gene
Disorders for TTPA Gene
(28) MalaCards diseases for TTPA Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| vitamin e, familial isolated deficiency of |
|
|
| ataxia with vitamin e deficiency |
|
|
| friedreich ataxia |
|
|
| abetalipoproteinemia |
|
|
| autosomal recessive disease |
|
|
Search TTPA in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
TTPA_HUMAN- Ataxia with isolated vitamin E deficiency (AVED) [MIM:277460]: An autosomal recessive disease characterized by undetectable or markedly reduced plasma levels of vitamin E, spinocerebellar degeneration, ataxia, areflexia and proprioception loss. {ECO:0000269 PubMed:15065857, ECO:0000269 PubMed:15300460, ECO:0000269 PubMed:7566022, ECO:0000269 PubMed:8602747, ECO:0000269 PubMed:9463307}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for TTPA
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for Genatlas for TTPA Gene
Publications for TTPA Gene
- Human alpha-tocopherol transfer protein: cDNA cloning, expression and chromosomal localization. (PMID: 7887897) Arita M … Inoue K (The Biochemical journal 1995) 2 3 4 23
- Ataxia with isolated vitamin E deficiency is caused by mutations in the alpha-tocopherol transfer protein. (PMID: 7719340) Ouahchi K … Koenig M (Nature genetics 1995) 2 3 4 23
- Association of variants in two vitamin e transport genes with circulating vitamin e concentrations and prostate cancer risk. (PMID: 19190344) Wright ME … Albanes D (Cancer research 2009) 3 23 41
- Ataxia with isolated vitamin E deficiency: neurological phenotype, clinical follow-up and novel mutations in TTPA gene in Italian families. (PMID: 15300460) Mariotti C … Di Donato S (Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2004) 3 4 23
- Molecular determinants of heritable vitamin E deficiency. (PMID: 15065857) Morley S … Manor D (Biochemistry 2004) 3 4 23
ExternalLinks
Products for TTPA Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for TTPA
- Search Origene for MassSpec and Protein Over-expression Lysates for TTPA
- Origene Custom Protein Services for TTPA
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TTPA
- Browse OriGene Inhibitory RNA Products For TTPA
- OriGene qPCR primer pairs for TTPA
- OriGene CRISPR knockouts for TTPA
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TTPA
- Sino Biological Human cDNA Clone for TTPA
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for TTPA
- Novus Biologicals proteins for TTPA
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for TTPA (AFLGC-Ttpa)
- VectorBuilder Custom and pre-made DNA vectors for TTPA (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for TTPA (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for TTPA (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for TTPA CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for TTPA
- antibodies-online: Show 12 available TTPA Antibodies ranked by validation data
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- antibodies-online: Show 17 available TTPA Elisa Kits ranked by validation data
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- Quality Products:
- antibodies-online: Show 7 available TTPA Proteins ranked by validation data
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- Quality Products:
- Horizon Cell Lines for TTPA
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TTPA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TTPA
- Search GeneCopoeia for miRNA 3'UTR Target clone products for TTPA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TTPA
Sources for TTPA Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
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