Aliases for TTC4 Gene
External Ids for TTC4 Gene
Previous GeneCards Identifiers for TTC4 Gene
This gene encodes a protein that contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions and chaperone activity. The encoded protein interacts with heat shock proteins 70 and 90. Alternative splicing results in multiple transcript variants. Naturally-occuring readthrough transcription occurs from upstream gene MROH (maestro heat-like repeat family member 7) to this gene. [provided by RefSeq, Apr 2014]
GeneCards Summary for TTC4 Gene
TTC4 (Tetratricopeptide Repeat Domain 4) is a Protein Coding gene. Diseases associated with TTC4 include Sporadic Breast Cancer and Central Nervous System Leukemia. An important paralog of this gene is SPAG1.
UniProtKB/Swiss-Prot Summary for TTC4 Gene
May act as a co-chaperone for HSP90AB1 (PubMed:18320024). Promotes Sendai virus (SeV)-induced host cell innate immune responses (PubMed:29251827).