TTC28-AS1 Gene (RNA Gene)

TTC28 Antisense RNA 1

GC22P027920
GIFtS:
17
See more...

Aliases for TTC28-AS1 Gene

Data sources for TTC28-AS1 Gene:

Subcategory (RNA class) for TTC28-AS1 Gene

lncRNA

Aliases for TTC28-AS1 Gene

External Ids for TTC28-AS1 Gene

Previous HGNC Symbols for TTC28-AS1 Gene

  • TTC28AS
  • TTC28-AS

Previous GeneCards Identifiers for TTC28-AS1 Gene

  • GC22P028318
  • GC22P028321
  • GC22P028327

Summaries for TTC28-AS1 Gene

GeneCards Summary for TTC28-AS1 Gene

TTC28-AS1 (TTC28 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class.

Rfam classification for TTC28-AS1 Gene

  • TTC28 antisense RNA 1 conserved region 1
  • TTC28 antisense RNA 1 conserved region 2
  • TTC28 antisense RNA 1 conserved region 3
  • TTC28 antisense RNA 1 conserved region 4

Additional gene information for TTC28-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for TTC28-AS1 Gene

Genomics for TTC28-AS1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for TTC28-AS1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TTC28-AS1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for TTC28-AS1 Gene

Latest Assembly
chr22:27,919,367-28,008,581
(GRCh38/hg38)
Size:
89,215 bases
Orientation:
Plus strand

Previous Assembly
chr22:28,315,364-28,398,667
(GRCh37/hg19 by Entrez Gene)
Size:
83,304 bases
Orientation:
Plus strand

chr22:28,315,364-28,404,569
(GRCh37/hg19 by Ensembl)
Size:
89,206 bases
Orientation:
Plus strand

Genomic View for TTC28-AS1 Gene

Genes around TTC28-AS1 on UCSC Golden Path with GeneCards custom track
TTC28-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
TTC28-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TTC28-AS1 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for TTC28-AS1 Gene

Proteins for TTC28-AS1 Gene

Products:

  1. Antibodies for research
  2. Protein products for research
  3. Assay products for research

Post-translational modifications for TTC28-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TTC28-AS1 Gene

Domains & Families for TTC28-AS1 Gene

Gene Families for TTC28-AS1 Gene

HGNC:
genes like me logo Genes that share domains with TTC28-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TTC28-AS1 Gene

Function for TTC28-AS1 Gene

Products:

  1. Animal Models for research
  2. CRISPR products for research
  3. miRNA products for research
  4. Inhibitory RNAs for research
  5. Clone products for research
  6. Cell Lines for research

Phenotypes From GWAS Catalog for TTC28-AS1 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TTC28-AS1 Gene

Localization for TTC28-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TTC28-AS1 gene
Compartment Confidence
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TTC28-AS1 Gene

Pathways & Interactions for TTC28-AS1 Gene

PathCards logo

SuperPathways for TTC28-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TTC28-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for TTC28-AS1 Gene

Drugs & Compounds for TTC28-AS1 Gene

Products:

  1. Drug products for research
No Compound Related Data Available

Transcripts for TTC28-AS1 Gene

Products:

  1. CRISPR products for research
  2. miRNA products for research
  3. Inhibitory RNAs for research
  4. Clone products for research

Non-coding RNA (ncRNA) Transcripts from RNAcentral for TTC28-AS1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00008BCAB4_9606 lncRNA 848 4

Ensembl: ENST00000419253 (view in UCSC) ,

LncBook: HSALNT0276608,

LNCipedia: TTC28-AS1:7,

NONCODE: NONHSAT084611.2,

URS00008B4220_9606 lncRNA 706 4

Ensembl: ENST00000428818 (view in UCSC) ,

LncBook: HSALNT0276615,

LNCipedia: TTC28-AS1:12,

NONCODE: NONHSAT084616.2,

URS00008BC545_9606 lncRNA 811 3

Ensembl: ENST00000425112 (view in UCSC) ,

LNCipedia: TTC28-AS1:22,

NONCODE: NONHSAT084623.2,

URS00008B538A_9606 lncRNA 564 3

Ensembl: ENST00000430853 (view in UCSC) ,

LncBook: HSALNT0276603,

NONCODE: NONHSAT084608.2,

URS00008BA242_9606 lncRNA 5859 2

Ensembl: ENST00000428584 (view in UCSC) ,

NONCODE: NONHSAT084637.2,

TTC28-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for TTC28-AS1 Gene

10 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR products for research

Alternative Splicing Database (ASD) splice patterns (SP) for TTC28-AS1 Gene

No ASD Table

Relevant External Links for TTC28-AS1 Gene

GeneLoc Exon Structure for
TTC28-AS1

Expression for TTC28-AS1 Gene

Products:

  1. Primer products for research
  2. Gene Expression Assays for research

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TTC28-AS1 Gene

mRNA expression in normal human tissues for TTC28-AS1 Gene
mRNA expression by GTEx for TTC28-AS1 GenemRNA expression by BioGPS for TTC28-AS1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TTC28-AS1

SOURCE GeneReport for Unigene cluster for TTC28-AS1 Gene:

Hs.602319
genes like me logo Genes that share expression patterns with TTC28-AS1: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TTC28-AS1 Gene

Orthologs for TTC28-AS1 Gene

Evolution for TTC28-AS1 Gene

ENSEMBL:
Gene Tree for TTC28-AS1 (if available)
TreeFam:
Gene Tree for TTC28-AS1 (if available)

No data available for Orthologs for TTC28-AS1 Gene

Paralogs for TTC28-AS1 Gene

No data available for Paralogs for TTC28-AS1 Gene

Variants for TTC28-AS1 Gene

Products:

  1. SNP Genotyping and Copy Number Assays for research

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TTC28-AS1 Gene

SNP ID Clinical significance and condition Chr 22 pos Variation AA Info Type
rs143432636 Likely Benign: not provided 27,983,132(+) G/A
NM_001145418.1(TTC28):c.6535C>T (p.Arg2179Cys) 		MISSENSE
rs1601475038 Likely Benign: not provided 27,982,797(+) G/A
NM_001145418.1(TTC28):c.6870C>T (p.Tyr2290=) 		SYNONYMOUS
rs187345071 Benign: not provided 27,998,697(+) G/A
NM_001145418.1(TTC28):c.4962C>T (p.Leu1654=) 		NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS
rs189781469 Likely Benign: not provided 27,983,028(+) C/T
NM_001145418.1(TTC28):c.6639G>A (p.Ala2213=) 		SYNONYMOUS
rs200365104 Likely Benign: not provided 27,993,391(+) C/T
NM_001145418.1(TTC28):c.5372G>A (p.Arg1791Gln) 		MISSENSE

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for TTC28-AS1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for TTC28-AS1 Gene

Variant ID Type Subtype PubMed ID
esv3568347 CNV loss 25503493
esv3568348 CNV loss 25503493
nsv1129409 OTHER inversion 24896259
nsv473282 CNV novel sequence insertion 20440878
nsv522306 CNV loss 19592680

Additional Variant Information for TTC28-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TTC28-AS1

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TTC28-AS1 Gene

Disorders for TTC28-AS1 Gene

Additional Disease Information for TTC28-AS1

Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform

No disorders were found for TTC28-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TTC28-AS1 Gene

Publications for TTC28-AS1 Gene

  1. Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping. (PMID: 11258795) Hirosawa M … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2001) 2 3
  2. Deregulation of long noncoding RNA SNHG17 and TTC28-AS1 is associated with type 2 diabetes mellitus. (PMID: 31509021) Mohamadi M … Rahimipour A (Scandinavian journal of clinical and laboratory investigation 2019) 3
  3. A genome-wide association study on obesity and obesity-related traits. (PMID: 21552555) Wang K … Price RA (PloS one 2011) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
  5. A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins JE … Dunham I (Genome biology 2004) 3

ExternalLinks

View latest publications for TTC28-AS1 gene in Mastermind

Products for TTC28-AS1 Gene

Sources for TTC28-AS1 Gene