This gene encodes a member of TTC21 family, containing several tetratricopeptide repeat (TPR) domains. This protein is localized to the cilium axoneme, and may play a role in retrograde intraflagellar transport in cilia. Mutations in this gene are associated with various ciliopathies, nephronophthisis 12, and asphyxiating thoracic dystrophy 4. [provided by RefSeq, Oct 2011] See more...

Aliases for TTC21B Gene

Aliases for TTC21B Gene

  • Tetratricopeptide Repeat Domain 21B 2 3 5
  • Intraflagellar Transport 139 Homolog 3 4
  • Tetratricopeptide Repeat Protein 21B 3 4
  • TPR Repeat Protein 21B 3 4
  • IFT139 3 4
  • Putative Protein Product Of Nbla10696 3
  • Nbla10696 3
  • KIAA1992 4
  • IFT139B 3
  • JBTS11 3
  • NPHP12 3
  • SRTD4 3
  • ATD4 3
  • THM1 3

External Ids for TTC21B Gene

Previous GeneCards Identifiers for TTC21B Gene

  • GC02M166491
  • GC02M166713
  • GC02M158612

Summaries for TTC21B Gene

Entrez Gene Summary for TTC21B Gene

  • This gene encodes a member of TTC21 family, containing several tetratricopeptide repeat (TPR) domains. This protein is localized to the cilium axoneme, and may play a role in retrograde intraflagellar transport in cilia. Mutations in this gene are associated with various ciliopathies, nephronophthisis 12, and asphyxiating thoracic dystrophy 4. [provided by RefSeq, Oct 2011]

GeneCards Summary for TTC21B Gene

TTC21B (Tetratricopeptide Repeat Domain 21B) is a Protein Coding gene. Diseases associated with TTC21B include Nephronophthisis 12 and Short-Rib Thoracic Dysplasia 4 With Or Without Polydactyly. Among its related pathways are Intraflagellar transport and Signaling by Hedgehog. An important paralog of this gene is TTC21A.

UniProtKB/Swiss-Prot Summary for TTC21B Gene

  • Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs). Essential for retrograde trafficking of IFT-1, IFT-B and GPCRs (PubMed:27932497). Negatively modulates the SHH signal transduction (By similarity).

Additional gene information for TTC21B Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TTC21B Gene

Genomics for TTC21B Gene

GeneHancer (GH) Regulatory Elements for TTC21B Gene

Promoters and enhancers for TTC21B Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J165952 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 760.6 +0.2 171 4.1 E2F8 ZNF24 SP1 ZBTB40 CTCF ZBTB6 MLX SMARCE1 RBPJ POLR2A TTC21B lnc-SCN1A-2 SCN1A-AS1 ENSG00000232411 GALNT3 TTC21B-AS1
GH02J166371 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas 19.5 -420.2 -420165 6.4 ZBTB40 LCORL RBPJ SMARCE1 CTBP1 NR2F6 CREB1 MIXL1 RUNX1 CC2D1A SCN9A CSRNP3 TTC21B SCN1A piR-35674-293 SCN1A-AS1
GH02J165825 Enhancer 0.8 Ensembl 53.6 +128.4 128438 0.4 ZBTB6 LCORL NFIB BCL6B ZNF473 KLF14 ZBTB8A PRDM10 ZNF544 ZNF501 TTC21B ENSG00000235192 ENSG00000232411 RF00951-075 ENSG00000229195 LOC105373730
GH02J166410 Enhancer 1.2 FANTOM5 Ensembl ENCODE 30.8 -458.3 -458300 3.7 SMARCE1 HLF MAX DACH1 ZKSCAN8 MAFK BACH1 SMARCA4 TRIM24 EGR1 piR-31292-098 TTC21B ENSG00000232411 SCN9A lnc-SCN9A-2 SCN7A
GH02J166351 Enhancer 0.5 Ensembl ENCODE 17.3 -398.0 -397962 0.8 ZBTB40 ZNF507 TTC21B SCN9A RF01210-219 lnc-SCN7A-2 SCN1A-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TTC21B on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TTC21B gene promoter:
  • CREB
  • deltaCREB
  • FOXD3
  • GR
  • GR-alpha
  • GR-beta
  • Ik-2
  • Nkx2-2
  • TBP
  • TFIID

Genomic Locations for TTC21B Gene

Genomic Locations for TTC21B Gene
chr2:165,857,475-165,953,838
(GRCh38/hg38)
Size:
96,364 bases
Orientation:
Minus strand
chr2:166,713,985-166,810,353
(GRCh37/hg19)
Size:
96,369 bases
Orientation:
Minus strand

Genomic View for TTC21B Gene

Genes around TTC21B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TTC21B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TTC21B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TTC21B Gene

Proteins for TTC21B Gene

  • Protein details for TTC21B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z4L5-TT21B_HUMAN
    Recommended name:
    Tetratricopeptide repeat protein 21B
    Protein Accession:
    Q7Z4L5
    Secondary Accessions:
    • A8MUZ3
    • Q3LIE4
    • Q53T84
    • Q6P4A1
    • Q6PIF5
    • Q8NCN3
    • Q96MA4
    • Q9HAK8

    Protein attributes for TTC21B Gene

    Size:
    1316 amino acids
    Molecular mass:
    150937 Da
    Quaternary structure:
    • Component of the IFT complex A (IFT-A) complex (PubMed:20889716, PubMed:27932497). IFT-A complex is divided into a core subcomplex composed of IFT122:IFT140:WDR19 which is associated with TULP3 and a peripheral subcomplex composed of IFT43:WDR35:TTC21B (PubMed:27932497). Interacts directy with WDR35 and TTC21B (PubMed:27932497). Interacts with TTC25 (PubMed:25860617).
    SequenceCaution:
    • Sequence=AAY14750.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAB13836.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for TTC21B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TTC21B Gene

Post-translational modifications for TTC21B Gene

  • Ubiquitination at Lys184 and Lys308
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for TTC21B Gene

Domains & Families for TTC21B Gene

Gene Families for TTC21B Gene

Protein Domains for TTC21B Gene

Suggested Antigen Peptide Sequences for TTC21B Gene

GenScript: Design optimal peptide antigens:
  • Tetratricopeptide repeat protein 21B (TT21B_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q7Z4L5

UniProtKB/Swiss-Prot:

TT21B_HUMAN :
  • Belongs to the TTC21 family.
Family:
  • Belongs to the TTC21 family.
genes like me logo Genes that share domains with TTC21B: view

Function for TTC21B Gene

Molecular function for TTC21B Gene

UniProtKB/Swiss-Prot Function:
Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs). Essential for retrograde trafficking of IFT-1, IFT-B and GPCRs (PubMed:27932497). Negatively modulates the SHH signal transduction (By similarity).

Phenotypes From GWAS Catalog for TTC21B Gene

Gene Ontology (GO) - Molecular Function for TTC21B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IEA --
genes like me logo Genes that share ontologies with TTC21B: view
genes like me logo Genes that share phenotypes with TTC21B: view

Human Phenotype Ontology for TTC21B Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for TTC21B Gene

MGI Knock Outs for TTC21B:
  • Ttc21b Ttc21b<tm2a(KOMP)Wtsi>

Animal Model Products

CRISPR Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for TTC21B Gene

Localization for TTC21B Gene

Subcellular locations from UniProtKB/Swiss-Prot for TTC21B Gene

Cytoplasm, cytoskeleton, cilium axoneme.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TTC21B gene
Compartment Confidence
cytoskeleton 3
mitochondrion 2
nucleus 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for TTC21B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000790 nuclear chromatin IEA --
GO:0005737 cytoplasm IEA --
GO:0005856 cytoskeleton IEA --
GO:0005929 cilium TAS --
GO:0030991 intraciliary transport particle A IDA,IBA 20889716
genes like me logo Genes that share ontologies with TTC21B: view

Pathways & Interactions for TTC21B Gene

genes like me logo Genes that share pathways with TTC21B: view

Pathways by source for TTC21B Gene

Gene Ontology (GO) - Biological Process for TTC21B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription by RNA polymerase II IMP 22302990
GO:0007224 smoothened signaling pathway IEA --
GO:0008589 regulation of smoothened signaling pathway IEA --
GO:0021591 ventricular system development IEA --
GO:0021798 forebrain dorsal/ventral pattern formation IEA --
genes like me logo Genes that share ontologies with TTC21B: view

No data available for SIGNOR curated interactions for TTC21B Gene

Drugs & Compounds for TTC21B Gene

No Compound Related Data Available

Transcripts for TTC21B Gene

mRNA/cDNA for TTC21B Gene

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TTC21B Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20 ^ 21 ^
SP1: - -
SP2: -
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:

ExUns: 22a · 22b ^ 23 ^ 24a · 24b ^ 25 ^ 26a · 26b ^ 27a · 27b ^ 28 ^ 29 ^ 30a · 30b ^ 31a · 31b ^ 32 ^ 33 ^ 34 ^ 35
SP1: - - -
SP2:
SP3: - - - -
SP4:
SP5:
SP6: -
SP7:
SP8: -

Relevant External Links for TTC21B Gene

GeneLoc Exon Structure for
TTC21B
ECgene alternative splicing isoforms for
TTC21B

Expression for TTC21B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TTC21B Gene

Protein differential expression in normal tissues from HIPED for TTC21B Gene

This gene is overexpressed in Plasma (19.7), Pancreatic juice (13.7), Liver (10.3), and Ovary (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TTC21B Gene



NURSA nuclear receptor signaling pathways regulating expression of TTC21B Gene:

TTC21B

SOURCE GeneReport for Unigene cluster for TTC21B Gene:

Hs.310672

Evidence on tissue expression from TISSUES for TTC21B Gene

  • Nervous system(4.3)
  • Adrenal gland(4.1)

Phenotype-based relationships between genes and organs from Gene ORGANizer for TTC21B Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • endocrine
  • immune
  • integumentary
  • lymphatic
  • nervous
  • reproductive
  • respiratory
  • skeletal muscle
  • skeleton
  • urinary
Regions:
Head and neck:
  • brain
  • cheek
  • chin
  • cranial nerve
  • ear
  • eye
  • face
  • head
  • jaw
  • lip
  • mandible
  • maxilla
  • mouth
  • nose
  • outer ear
  • skull
  • tooth
Thorax:
  • chest wall
  • clavicle
  • heart
  • lung
  • rib
  • rib cage
  • scapula
  • sternum
Abdomen:
  • abdominal wall
  • biliary tract
  • gallbladder
  • intestine
  • kidney
  • large intestine
  • liver
  • pancreas
  • small intestine
  • spleen
Pelvis:
  • pelvis
  • penis
  • testicle
  • ureter
  • urinary bladder
  • vagina
  • vulva
Limb:
  • arm
  • digit
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • lower limb
  • nail
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
General:
  • blood
  • blood vessel
  • coagulation system
  • peripheral nervous system
  • skin
  • spinal column
  • vertebrae
genes like me logo Genes that share expression patterns with TTC21B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TTC21B Gene

Orthologs for TTC21B Gene

This gene was present in the common ancestor of animals.

Orthologs for TTC21B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TTC21B 33 32
  • 99.52 (n)
OneToOne
dog
(Canis familiaris)
Mammalia TTC21B 33 32
  • 90.07 (n)
OneToOne
cow
(Bos Taurus)
Mammalia TTC21B 33 32
  • 89.67 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ttc21b 32
  • 84.03 (n)
oppossum
(Monodelphis domestica)
Mammalia TTC21B 33
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ttc21b 17 33 32
  • 83.5 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia TTC21B 33
  • 77 (a)
OneToOne
chicken
(Gallus gallus)
Aves TTC21B 33 32
  • 75.29 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TTC21B 33
  • 68 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ttc21b 32
  • 72.42 (n)
zebrafish
(Danio rerio)
Actinopterygii ttc21b 33 32
  • 65.57 (n)
OneToOne
sbcb947 32
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000136 32
  • 46.79 (n)
worm
(Caenorhabditis elegans)
Secernentea ZK328.7 33 32
  • 47.38 (n)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 33
  • 46 (a)
OneToMany
Cin.13610 32
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.13610 32
Species where no ortholog for TTC21B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TTC21B Gene

ENSEMBL:
Gene Tree for TTC21B (if available)
TreeFam:
Gene Tree for TTC21B (if available)
Aminode:
Evolutionary constrained regions (ECRs) for TTC21B: view image

Paralogs for TTC21B Gene

Paralogs for TTC21B Gene

(1) SIMAP similar genes for TTC21B Gene using alignment to 2 proteins:

  • TT21B_HUMAN
  • H9KV93_HUMAN
genes like me logo Genes that share paralogs with TTC21B: view

Variants for TTC21B Gene

Sequence variations from dbSNP and Humsavar for TTC21B Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs10176588 benign, not specified, Joubert syndrome, Jeune thoracic dystrophy 165,913,610(-) A/G coding_sequence_variant, synonymous_variant
rs1040877016 Nephronophthisis 12 (NPHP12) [MIM:613820] 165,883,978(-) T/C 3_prime_UTR_variant, coding_sequence_variant, genic_downstream_transcript_variant, missense_variant
rs1060504949 likely-benign, Jeune thoracic dystrophy, Nephronophthisis 165,874,767(-) A/G 3_prime_UTR_variant, coding_sequence_variant, genic_downstream_transcript_variant, synonymous_variant
rs111867313 benign, Joubert syndrome, Jeune thoracic dystrophy 165,953,850(-) C/T upstream_transcript_variant
rs112868646 benign, likely-benign, not specified, Jeune thoracic dystrophy, Joubert syndrome, Nephronophthisis, not provided, - 165,931,814(-) T/C 5_prime_UTR_variant, coding_sequence_variant, missense_variant

Structural Variations from Database of Genomic Variants (DGV) for TTC21B Gene

Variant ID Type Subtype PubMed ID
nsv1149755 CNV insertion 26484159
nsv507045 OTHER sequence alteration 20534489
nsv834445 CNV gain+loss 17160897

Variation tolerance for TTC21B Gene

Residual Variation Intolerance Score: 67.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.63; 72.62% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TTC21B Gene

Human Gene Mutation Database (HGMD)
TTC21B
SNPedia medical, phenotypic, and genealogical associations of SNPs for
TTC21B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TTC21B Gene

Disorders for TTC21B Gene

MalaCards: The human disease database

(22) MalaCards diseases for TTC21B Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, DISEASES, and GeneCards

UniProtKB/Swiss-Prot

TT21B_HUMAN
  • Note=Ciliary dysfunction leads to a broad spectrum of disorders, collectively termed ciliopathies. Overlapping clinical features include retinal degeneration, renal cystic disease, skeletal abnormalities, fibrosis of various organ, and a complex range of anatomical and functional defects of the central and peripheral nervous system. The ciliopathy range of diseases includes Meckel-Gruber syndrome, Bardet-Biedl syndrome, Joubert syndrome, nephronophtisis, Senior-Loken syndrome, and Jeune asphyxiating thoracic dystrophy among others. TTC21B is causally associated with diverse ciliopathies. It also acts as a modifier gene across the ciliopathy spectrum, interacting in trans with mutations in other ciliopathy-causing genes and contributing to disease manifestation and severity. {ECO:0000269 PubMed:21258341}.
  • Nephronophthisis 12 (NPHP12) [MIM:613820]: An autosomal recessive disorder resulting in end-stage renal disease. It is a progressive tubulo-interstitial kidney disorder histologically characterized by modifications of the tubules with thickening of the basement membrane, interstitial fibrosis and, in the advanced stages, medullary cysts. Some patients manifest extra-renal features including retinal, skeletal and central nervous system defects. {ECO:0000269 PubMed:21258341}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Short-rib thoracic dysplasia 4 with or without polydactyly (SRTD4) [MIM:613819]: A form of short-rib thoracic dysplasia, a group of autosomal recessive ciliopathies that are characterized by a constricted thoracic cage, short ribs, shortened tubular bones, and a 'trident' appearance of the acetabular roof. Polydactyly is variably present. Non-skeletal involvement can include cleft lip/palate as well as anomalies of major organs such as the brain, eye, heart, kidneys, liver, pancreas, intestines, and genitalia. Some forms of the disease are lethal in the neonatal period due to respiratory insufficiency secondary to a severely restricted thoracic cage, whereas others are compatible with life. Disease spectrum encompasses Ellis-van Creveld syndrome, asphyxiating thoracic dystrophy (Jeune syndrome), Mainzer-Saldino syndrome, and short rib-polydactyly syndrome. {ECO:0000269 PubMed:21258341}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Joubert syndrome 11 (JBTS11) [MIM:613820]: A disorder presenting with cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay. Neuroradiologically, it is characterized by cerebellar vermian hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar tooth sign). Additional variable features include retinal dystrophy and renal disease. {ECO:0000269 PubMed:21258341, ECO:0000269 PubMed:22425360}. Note=The disease may be caused by mutations affecting the gene represented in this entry.

Additional Disease Information for TTC21B

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with TTC21B: view

No data available for Genatlas for TTC21B Gene

Publications for TTC21B Gene

  1. TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum. (PMID: 21258341) Davis EE … Katsanis N (Nature genetics 2011) 2 3 4 56
  2. Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method. (PMID: 12056414) Ohara O … Koseki H (DNA research : an international journal for rapid publication of reports on genes and genomes 2002) 2 3 4 56
  3. Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors. (PMID: 27932497) Hirano T … Nakayama K (Molecular biology of the cell 2017) 3 4 56
  4. TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia. (PMID: 20889716) Mukhopadhyay S … Jackson PK (Genes & development 2010) 3 4 56
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 56

Products for TTC21B Gene

Sources for TTC21B Gene