Aliases for TSPEAR-AS2 Gene

Subcategory (RNA class) for TSPEAR-AS2 Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for TSPEAR-AS2 Gene

  • TSPEAR Antisense RNA 2 2 3 4 5
  • TSPEAR-AS2 2 5 165
  • C21orf90 3 4
  • Putative Uncharacterized Protein TSPEAR-AS2 4
  • Chromosome 21 Open Reading Frame 90 2
  • TSPEAR Antisense Gene Protein 2 4
  • NONHSAG033038.2 91
  • HSALNG0133549 164

External Ids for TSPEAR-AS2 Gene

Previous HGNC Symbols for TSPEAR-AS2 Gene

  • C21orf90

Previous GeneCards Identifiers for TSPEAR-AS2 Gene

  • GC21P044518
  • GC21P044519
  • GC21P044625
  • GC21P044638
  • GC21P044639
  • GC21P044656
  • GC21P044531
  • GC21P044542
  • GC21P044554
  • GC21P044567
  • GC21P044580
  • GC21P044591
  • GC21P044603
  • GC21P044604

Summaries for TSPEAR-AS2 Gene

GeneCards Summary for TSPEAR-AS2 Gene

TSPEAR-AS2 (TSPEAR Antisense RNA 2) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for TSPEAR-AS2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TSPEAR-AS2 Gene

Genomics for TSPEAR-AS2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for TSPEAR-AS2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TSPEAR-AS2 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for TSPEAR-AS2 Gene

Genomic Locations for TSPEAR-AS2 Gene
chr21:44,517,215-44,525,952
(GRCh38/hg38)
Size:
8,738 bases
Orientation:
Plus strand
chr21:45,937,098-45,945,835
(GRCh37/hg19)
Size:
8,738 bases
Orientation:
Plus strand

Genomic View for TSPEAR-AS2 Gene

Genes around TSPEAR-AS2 on UCSC Golden Path with GeneCards custom track
TSPEAR-AS2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
TSPEAR-AS2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TSPEAR-AS2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TSPEAR-AS2 Gene

Proteins for TSPEAR-AS2 Gene

  • Protein details for TSPEAR-AS2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P59090-TSAS2_HUMAN
    Recommended name:
    Putative uncharacterized protein TSPEAR-AS2
    Protein Accession:
    P59090
    Secondary Accessions:
    • Q3MIX8

    Protein attributes for TSPEAR-AS2 Gene

    Size:
    65 amino acids
    Molecular mass:
    7097 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TSPEAR-AS2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TSPEAR-AS2 Gene

Post-translational modifications for TSPEAR-AS2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TSPEAR-AS2 Gene

Domains & Families for TSPEAR-AS2 Gene

Gene Families for TSPEAR-AS2 Gene

Protein Domains for TSPEAR-AS2 Gene

ProtoNet:
genes like me logo Genes that share domains with TSPEAR-AS2: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TSPEAR-AS2 Gene

Function for TSPEAR-AS2 Gene

Phenotypes From GWAS Catalog for TSPEAR-AS2 Gene

Phenotypes for TSPEAR-AS2 Gene

genes like me logo Genes that share phenotypes with TSPEAR-AS2: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TSPEAR-AS2 Gene

Localization for TSPEAR-AS2 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TSPEAR-AS2 gene
Compartment Confidence
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TSPEAR-AS2 Gene

Pathways & Interactions for TSPEAR-AS2 Gene

PathCards logo

SuperPathways for TSPEAR-AS2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TSPEAR-AS2 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for TSPEAR-AS2 Gene

Drugs & Compounds for TSPEAR-AS2 Gene

No Compound Related Data Available

Transcripts for TSPEAR-AS2 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for TSPEAR-AS2 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075A9E0_9606 lncRNA 1045 5

HGNC: 16428,

RefSeq: NR_026547,

LncBook: HSALNT0274502,

LNCipedia: TSPEAR-AS2:1,

NONCODE: NONHSAT191059.1,

URS00007CADC6_9606 lncRNA 2422 4

Ensembl: ENST00000354333 (view in UCSC) ,

LncBook: HSALNT0274504,

LNCipedia: TSPEAR-AS2:4,

NONCODE: NONHSAT191060.1,

URS00007D94A1_9606 lncRNA 345 3

Ensembl: ENST00000465978 (view in UCSC) ,

LncBook: HSALNT0274506,

NONCODE: NONHSAT082865.2,

URS000075BBA3_9606 lncRNA 971 2

RefSeq: NR_026548,

LNCipedia: TSPEAR-AS2:2,

URS00007BC2CE_9606 lncRNA 823 2

Ensembl: ENST00000330490 (view in UCSC) ,

LNCipedia: TSPEAR-AS2:3,

TSPEAR-AS2 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for TSPEAR-AS2 Gene

1 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for TSPEAR-AS2 Gene

No ASD Table

Relevant External Links for TSPEAR-AS2 Gene

GeneLoc Exon Structure for
TSPEAR-AS2

Expression for TSPEAR-AS2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TSPEAR-AS2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TSPEAR-AS2

mRNA Expression by UniProt/SwissProt for TSPEAR-AS2 Gene:

P59090-TSAS2_HUMAN
Tissue specificity: Widely expressed. Not expressed in liver and muscle.
genes like me logo Genes that share expression patterns with TSPEAR-AS2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TSPEAR-AS2 Gene

Orthologs for TSPEAR-AS2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TSPEAR-AS2 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia C21orf90 31
  • 98 (a)
OneToOne
Species where no ortholog for TSPEAR-AS2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for TSPEAR-AS2 Gene

ENSEMBL:
Gene Tree for TSPEAR-AS2 (if available)
TreeFam:
Gene Tree for TSPEAR-AS2 (if available)

Paralogs for TSPEAR-AS2 Gene

No data available for Paralogs for TSPEAR-AS2 Gene

Variants for TSPEAR-AS2 Gene

Additional dbSNP identifiers (rs#s) for TSPEAR-AS2 Gene

Structural Variations from Database of Genomic Variants (DGV) for TSPEAR-AS2 Gene

Variant ID Type Subtype PubMed ID
esv2723638 CNV deletion 23290073
esv33817 CNV loss 17666407
nsv1055163 CNV gain 25217958
nsv1058359 CNV gain 25217958
nsv587803 CNV loss 21841781
nsv587804 CNV loss 21841781
nsv953646 CNV deletion 24416366

Variation tolerance for TSPEAR-AS2 Gene

Gene Damage Index Score: 0.05; 1.12% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TSPEAR-AS2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TSPEAR-AS2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TSPEAR-AS2 Gene

Disorders for TSPEAR-AS2 Gene

No disorders were found for TSPEAR-AS2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TSPEAR-AS2 Gene

Publications for TSPEAR-AS2 Gene

  1. Nineteen additional unpredicted transcripts from human chromosome 21. (PMID: 12036297) Reymond A … Antonarakis SE (Genomics 2002) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3
  5. The DNA sequence of human chromosome 21. (PMID: 10830953) Hattori M … Chromosome 21 mapping and sequencing consortium (Nature 2000) 4

Products for TSPEAR-AS2 Gene

Sources for TSPEAR-AS2 Gene