Aliases for TSPAN5 Gene
External Ids for TSPAN5 Gene
Previous HGNC Symbols for TSPAN5 Gene
Previous GeneCards Identifiers for TSPAN5 Gene
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
GeneCards Summary for TSPAN5 Gene
TSPAN5 (Tetraspanin 5) is a Protein Coding gene. Diseases associated with TSPAN5 include Coffin-Siris Syndrome 3 and Autosomal Dominant Non-Syndromic Intellectual Disability. Gene Ontology (GO) annotations related to this gene include enzyme binding. An important paralog of this gene is TSPAN17.
UniProtKB/Swiss-Prot Summary for TSPAN5 Gene
Regulates ADAM10 maturation and trafficking to the cell surface. Promotes ADAM10-mediated cleavage of CD44.