Aliases for TSPAN4 Gene
External Ids for TSPAN4 Gene
Previous HGNC Symbols for TSPAN4 Gene
Previous GeneCards Identifiers for TSPAN4 Gene
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for TSPAN4 Gene
TSPAN4 (Tetraspanin 4) is a Protein Coding gene. Diseases associated with TSPAN4 include Deafness, Autosomal Recessive 67 and Spastic Paraplegia 2, X-Linked. Gene Ontology (GO) annotations related to this gene include integrin binding and antigen binding. An important paralog of this gene is TSPAN9.