Aliases for TSPAN2 Gene
External Ids for TSPAN2 Gene
Previous GeneCards Identifiers for TSPAN2 Gene
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
GeneCards Summary for TSPAN2 Gene
TSPAN2 (Tetraspanin 2) is a Protein Coding gene. Diseases associated with TSPAN2 include Migraine, Familial Hemiplegic, 2 and Vasculopathy, Retinal, With Cerebral Leukoencephalopathy And Systemic Manifestations. An important paralog of this gene is CD9.
UniProtKB/Swiss-Prot Summary for TSPAN2 Gene
May play a role in signalling in oligodendrocytes in the early stages of their terminal differentiation into myelin-forming glia and may also function in stabilizing the mature sheath.