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TSPAN11 (Tetraspanin 11) is a Protein Coding gene. Diseases associated with TSPAN11 include Kallmann Syndrome. An important paralog of this gene is CD151.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH12J030926 | Promoter/Enhancer | 2 | EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas | 603 | +1.0 | 1005 | 2.9 | KLF9 ZBTB20 ZBTB48 ZBTB26 ZBTB17 MYC POLR2A EZH2 ZFHX2 ZNF335 | TSPAN11 piR-57551 lnc-CAPRIN2-2 DDX11 | |
GH12J030930 | Promoter | 0.6 | EPDnew | 600.7 | +4.0 | 3981 | 0.1 | NR2F2 POLR2A SMARCA4 | TSPAN11 piR-57551 lnc-CAPRIN2-2 DDX11 | |
GH12J030925 | Enhancer | 0.3 | CraniofacialAtlas | 600.7 | -0.7 | -661 | 0.2 | EZH2 | TSPAN11 RF00017-1122 lnc-CAPRIN2-2 CAPRIN2 | |
GH12J030908 | Enhancer | 0.9 | Ensembl ENCODE CraniofacialAtlas | 20.1 | -17.3 | -17295 | 2.9 | PRDM10 FOXA2 MAFF MAFK JUND SMAD4 BCL6 NFIA GLIS1 SOX5 | TSPAN11 LINC00941 RF00017-1122 CAPRIN2 | |
GH12J030874 | Enhancer | 0.7 | Ensembl | 12.5 | -51.4 | -51427 | 0.4 | PRDM10 ZNF629 ZNF692 ZIC2 ZNF561 TCF7L2 ZXDB TSHZ1 OSR2 BCL11A | TSPAN11 LOC107984476 PPIAP44 lnc-TSPAN11-6 ENSG00000285517 CAPRIN2 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005887 | integral component of plasma membrane | IBA | 21873635 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016477 | cell migration | IBA | 21873635 |
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||||
SP2: | |||||||||||||
SP3: | |||||||||||||
SP4: |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | TSPAN11 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | TSPAN11 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | TSPAN11 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Tspan11 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Tspan11 30 17 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | TSPAN11 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | TSPAN11 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | -- 31 |
|
ManyToMany | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC101732684 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | tspan11 30 31 |
|
OneToOne | |
Fruit Fly (Drosophila melanogaster) |
Insecta | Tsp74F 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.8828 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs2075333 | - | p.Val190Ala |
Disorder | Aliases | PubMed IDs |
---|---|---|
kallmann syndrome |
|
|