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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provide... See more...
Aliases for TSPAN1 Gene
Aliases for TSPAN1 Gene
External Ids for TSPAN1 Gene
- HGNC: 20657
- Entrez Gene: 10103
- Ensembl: ENSG00000117472
- OMIM: 613170
- UniProtKB: O60635
Previous GeneCards Identifiers for TSPAN1 Gene
- GC01P046360
- GC01P046640
- GC01P044755
Summaries for TSPAN1 Gene
-
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
GeneCards Summary for TSPAN1 Gene
TSPAN1 (Tetraspanin 1) is a Protein Coding gene. Diseases associated with TSPAN1 include Retinitis Pigmentosa 76 and Muscle Eye Brain Disease. An important paralog of this gene is TSPAN18.
Additional gene information for TSPAN1 Gene
- HGNC(20657)
- Entrez Gene(10103)
- Ensembl(ENSG00000117472)
- OMIM(613170)
- UniProtKB(O60635)
- Open Targets Platform(ENSG00000117472)
- Search for TSPAN1 at DataMed
- Search for TSPAN1 at HumanCyc
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TSPAN1 Gene
Genomics for TSPAN1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for TSPAN1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around TSPAN1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TSPAN1
- Top Transcription factor binding sites by QIAGEN in the TSPAN1 gene promoter:
-
- AML1a
- Bach1
- E47
- GATA-2
- Hand1
- HNF-4alpha1
- HNF-4alpha2
- Roaz
Genomic Locations for TSPAN1 Gene
Genomic Locations for TSPAN1 Gene
- chr1:46,175,073-46,196,489
- (GRCh38/hg38)
- Size:
- 21,417 bases
- Orientation:
- Plus strand
- chr1:46,640,745-46,651,634
- (GRCh37/hg19)
- Size:
- 10,890 bases
- Orientation:
- Plus strand
Genomic View for TSPAN1 Gene
Genes around TSPAN1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p34.1 by HGNC
- 1p34.1 by Entrez Gene
- 1p34.1 by Ensembl
TSPAN1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TSPAN1 Gene
Proteins for TSPAN1 Gene
-
Protein details for TSPAN1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O60635-TSN1_HUMAN
- Recommended name:
- Tetraspanin-1
- Protein Accession:
- O60635
- D3DQ14
- O60745
- Q5VST0
Protein attributes for TSPAN1 Gene
- Size:
- 241 amino acids
- Molecular mass:
- 26301 Da
- Quaternary structure:
- No Data Available
Protein Expression for TSPAN1 Gene
Post-translational modifications for TSPAN1 Gene
Other Protein References for TSPAN1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- GeneTex Anti-Tetraspan 1 antibody
-
Custom Antibody ServicesOriGene Antibodies for TSPAN1
- Novus Biologicals Antibodies for TSPAN1
-
Abcam antibodies for TSPAN1
- Invitrogen Antibodies for TSPAN1 (AFLGC-TSPAN1)
-
Santa Cruz Biotechnology (SCBT) Antibodies for TSPAN1
- Sino Biological Antibodies for TSPAN1
Protein Products
-
OriGene Purified Proteins for TSPAN1
- Search Origene for MassSpec and Protein Over-expression Lysates for TSPAN1
- Origene Custom Protein Services for TSPAN1
- Sino Biological Cell Lysates for TSPAN1
- Sino Biological Recombinant Proteins for TSPAN1
- antibodies-online: Show 9 available TSPAN1 Proteins ranked by validation data
- Compare Top TSPAN1 Proteins
-
Quality Products:
-
Abcam proteins for TSPAN1
Assay Products
- antibodies-online: Show 5 available TSPAN1 Elisa Kits ranked by validation data
- Compare Top TSPAN1 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for TSPAN1 Gene
Domains & Families for TSPAN1 Gene
Gene Families for TSPAN1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for TSPAN1 Gene
- InterPro:
- Blocks:
-
- Transmembrane four family signature
- ProtoNet:
Suggested Antigen Peptide Sequences for TSPAN1 Gene
- GenScript: Design optimal peptide antigens:
-
- Tetraspanin TM4-C (TSN1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O60635- Family:
-
- Belongs to the tetraspanin (TM4SF) family.
Function for TSPAN1 Gene
Phenotypes From GWAS Catalog for TSPAN1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 21836059 |
Phenotypes for TSPAN1 Gene
Animal Model Products
-
Taconic Biosciences Mouse Models for TSPAN1
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TSPAN1 - Select products 50% OFF >
- * TSPAN1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for TSPAN1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TSPAN1
-
Santa Cruz Biotechnology (SCBT) CRISPR for TSPAN1
miRNA for TSPAN1 Gene
- miRTarBase miRNAs that target TSPAN1
-
- hsa-miR-573 (MIRT438319)
- hsa-miR-31-5p (MIRT472350)
- hsa-miR-4313 (MIRT472351)
- hsa-miR-6793-3p (MIRT472352)
- hsa-miR-4673 (MIRT472353)
- hsa-miR-4645-5p (MIRT472354)
- hsa-miR-103b (MIRT472355)
- hsa-miR-4742-5p (MIRT472356)
- hsa-miR-4733-3p (MIRT472357)
- hsa-miR-7853-5p (MIRT472358)
- hsa-miR-105-5p (MIRT472359)
- hsa-miR-449b-3p (MIRT472360)
- hsa-miR-1911-3p (MIRT472361)
- hsa-miR-365b-3p (MIRT472362)
- hsa-miR-3915 (MIRT472363)
- hsa-miR-365a-3p (MIRT472364)
- hsa-miR-4736 (MIRT472365)
- hsa-miR-657 (MIRT472366)
- hsa-miR-3928-3p (MIRT472367)
- hsa-miR-4495 (MIRT472368)
- hsa-miR-1252-3p (MIRT472369)
- hsa-miR-3646 (MIRT472370)
- hsa-miR-3662 (MIRT472371)
- hsa-miR-613 (MIRT472372)
- hsa-miR-206 (MIRT472373)
- hsa-miR-1-3p (MIRT472374)
- hsa-miR-3941 (MIRT612727)
- hsa-miR-153-5p (MIRT612728)
- hsa-miR-4789-3p (MIRT612729)
- hsa-miR-603 (MIRT612730)
- hsa-miR-8485 (MIRT612731)
- hsa-miR-362-3p (MIRT612732)
- hsa-miR-329-3p (MIRT612733)
- hsa-miR-4789-5p (MIRT616947)
- hsa-miR-34a-3p (MIRT627978)
- hsa-miR-607 (MIRT639491)
- hsa-miR-6749-3p (MIRT639492)
- hsa-miR-660-3p (MIRT639493)
- hsa-miR-5193 (MIRT639494)
- hsa-miR-483-3p (MIRT639495)
- hsa-miR-1277-5p (MIRT655886)
- hsa-miR-5011-5p (MIRT655887)
- hsa-miR-190a-3p (MIRT675943)
- hsa-miR-548c-3p (MIRT708018)
- hsa-miR-584-5p (MIRT722952)
- hsa-miR-8068 (MIRT722953)
- hsa-miR-5087 (MIRT722954)
- hsa-miR-6830-5p (MIRT722955)
- hsa-miR-758-5p (MIRT722956)
- hsa-miR-218-2-3p (MIRT722957)
- hsa-miR-651-3p (MIRT722958)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TSPAN1
- Browse OriGene Inhibitory RNA Products For TSPAN1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TSPAN1
Clone Products
- Applied Biological Materials (abm): Clones for TSPAN1 - Select products 50% OFF >
- * TSPAN1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TSPAN1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TSPAN1
Cell Line Products
-
Horizon Cell Lines for TSPAN1
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TSPAN1 Gene
Localization for TSPAN1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TSPAN1 Gene
- Lysosome membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 4 |
| nucleus | 4 |
| lysosome | 3 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| cytosol | 1 |
| golgi apparatus | 1 |
- Nucleoplasm (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IDA | 12115476 |
| GO:0005764 | lysosome | IEA | -- |
| GO:0005765 | lysosomal membrane | IEA | -- |
| GO:0005886 | plasma membrane | IDA | 21836059 |
Pathways & Interactions for TSPAN1 Gene
Interacting Proteins for TSPAN1 Gene
Selected Interacting proteins:
O60635-TSN1_HUMAN
ENSP00000361072
for TSPAN1 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for TSPAN1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0050821 | protein stabilization | IDA | 21836059 |
No data available for Pathways by source and SIGNOR curated interactions for TSPAN1 Gene
Transcripts for TSPAN1 Gene
mRNA/cDNA for TSPAN1 Gene
- 1 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000372003 1619 nts (view in UCSC)
- ENST00000464786 872 nts (view in UCSC)
- ENST00000469330 890 nts (view in UCSC)
- ENST00000470318 590 nts (view in UCSC)
- ENST00000472170 519 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for TSPAN1 - Select products 50% OFF >
- * TSPAN1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for TSPAN1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TSPAN1
-
Santa Cruz Biotechnology (SCBT) CRISPR for TSPAN1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TSPAN1
- Browse OriGene Inhibitory RNA Products For TSPAN1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TSPAN1
Clone Products
- Applied Biological Materials (abm): Clones for TSPAN1 - Select products 50% OFF >
- * TSPAN1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for TSPAN1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TSPAN1
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | · | 11c | · | 11d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP8: | - | - | |||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP10: | - | ||||||||||||||||||||||||||||||||||||||||
| SP11: |
Relevant External Links for TSPAN1 Gene
- GeneLoc Exon Structure for
- TSPAN1
Expression for TSPAN1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Bone (Muscoskeletal System)
- Kidney (Urinary System)
- Cartilage (Muscoskeletal System)
- Inner Cell Mass (Early Embryonic Tissues)
- Adipose (Muscoskeletal System)
- Epithelial Cells (Uncategorized)
- Liver (Hepatobiliary System)
-
Colon (Gastrointestinal Tract)
-
Prostate (Endocrine System)
-
Thyroid (Endocrine System)
-
Stomach (Gastrointestinal Tract)
mRNA differential expression in normal tissues according to GTEx for TSPAN1 Gene
This gene is overexpressed in Colon - Transverse (x17.4) and Kidney - Cortex (x10.6).
This gene is overexpressed in Urine (35.9) and Cervix (22.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for TSPAN1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TSPAN1
SOURCE GeneReport for Unigene cluster for TSPAN1 Gene:
Hs.38972Evidence on tissue expression from TISSUES for TSPAN1 Gene
- Intestine(4.9)
- Kidney(2.9)
- Stomach(2.9)
- Thyroid gland(2.5)
- Pancreas(2.4)
- Lung(2.3)
Primer Products
-
OriGene qPCR primer pairs for TSPAN1
-
OriGene qPCR primer pairs and template standards for TSPAN1
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TSPAN1 Gene
Orthologs for TSPAN1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | TSPAN1 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | TSPAN1 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | TSPAN1 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Tspan1 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Tspan1 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | TSPAN1 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | TSPAN1 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | TSPAN1 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | TSPAN1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | tspan1 30 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.24793 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | zgc:64085 30 |
|
||
| TSPAN1 31 |
|
OneToOne | |||
| -- 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Tsp66E 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | tsp-11 31 |
|
ManyToMany | |
| tsp-13 31 |
|
ManyToMany | |||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.10827 31 |
|
ManyToMany | |
| CSA.8143 31 |
|
ManyToMany | |||
| CSA.5127 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany |
- Species where no ortholog for TSPAN1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for TSPAN1 Gene
- ENSEMBL:
- Gene Tree for TSPAN1 (if available)
- TreeFam:
- Gene Tree for TSPAN1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for TSPAN1: view image
Paralogs for TSPAN1 Gene
Paralogs for TSPAN1 Gene
(12) SIMAP similar genes for TSPAN1 Gene using alignment to 1 proteins:
- TSN1_HUMAN
Variants for TSPAN1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TSPAN1 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 638451 | Uncertain Significance: POMGNT1-Related Disorders | 46,192,950(+) | C/A | MISSENSE_VARIANT | |
| 642934 | Likely Pathogenic: Congenital muscular dystrophy-dystroglycanopathy with mental retardation, type B3; Limb-girdle muscular dystrophy-dystroglycanopathy, type C3 | 46,194,843(+) | C/A | SPLICE_DONOR_VARIANT | |
| 643942 | Uncertain Significance: Congenital muscular dystrophy-dystroglycanopathy with mental retardation, type B3; Limb-girdle muscular dystrophy-dystroglycanopathy, type C3 | 46,189,477(+) | C/T | MISSENSE_VARIANT,INTRON_VARIANT | |
| 644042 | Uncertain Significance: Congenital muscular dystrophy-dystroglycanopathy with mental retardation, type B3; Limb-girdle muscular dystrophy-dystroglycanopathy, type C3 | 46,192,913(+) | C/G | MISSENSE_VARIANT | |
| 644389 | Uncertain Significance: Congenital muscular dystrophy-dystroglycanopathy with mental retardation, type B3; Limb-girdle muscular dystrophy-dystroglycanopathy, type C3 | 46,194,870(+) | G/A | MISSENSE_VARIANT |
Residual Variation Intolerance Score:
68.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.22;
24.44% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TSPAN1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TSPAN1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TSPAN1 Gene
Disorders for TSPAN1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| retinitis pigmentosa 76 |
|
|
| muscle eye brain disease |
|
|
| muscular dystrophy-dystroglycanopathy |
|
|
| retinitis pigmentosa |
|
|
Search TSPAN1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TSPAN1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for TSPAN1 Gene
Publications for TSPAN1 Gene
- Sequences and expression of six new members of the tetraspanin/TM4SF family. (PMID: 9714763) Todd SC … Levy S (Biochimica et biophysica acta 1998) 2 3 4
- Glycosylation of tetraspanin Tspan-1 at four distinct sites promotes its transition through the endoplasmic reticulum. (PMID: 19508227) Scholz CJ … Deissler H (Protein and peptide letters 2009) 3 4
- Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study. (PMID: 19139842) Lin X … Mooser V (Diabetologia 2009) 3 41
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Sequence and expression of seven new tetraspans. (PMID: 10719184) Serru V … Rubinstein E (Biochimica et biophysica acta 2000) 2 3
ExternalLinks
Products for TSPAN1 Gene
- Custom Antibody ServicesOriGene Antibodies for TSPAN1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for TSPAN1
- Search Origene for MassSpec and Protein Over-expression Lysates for TSPAN1
- Origene Custom Protein Services for TSPAN1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for TSPAN1
- Browse OriGene Inhibitory RNA Products For TSPAN1
- OriGene qPCR primer pairs for TSPAN1
- OriGene qPCR primer pairs and template standards for TSPAN1
- OriGene CRISPR knockouts for TSPAN1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TSPAN1
- Sino Biological Human cDNA Clone for TSPAN1
- Sino Biological Cell Lysates for TSPAN1
- Sino Biological Recombinant Proteins for TSPAN1
- Sino Biological Antibodies for TSPAN1
- Browse Sino Biological Assays
- Browse Recombinant Proteins
- Browse Antibodies
- Browse cDNA Clones
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- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for TSPAN1
- Novus Biologicals proteins and lysates for TSPAN1
- Browse Antibodies
- Browse Peptides and Proteins
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- Abcam antibodies for TSPAN1
- Abcam proteins for TSPAN1
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- Browse Primary Antibodies
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- Taconic Biosciences Mouse Models for TSPAN1
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for TSPAN1 (AFLGC-TSPAN1)
- VectorBuilder Custom and pre-made DNA vectors for TSPAN1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for TSPAN1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for TSPAN1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for TSPAN1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for TSPAN1
- antibodies-online: Show 17 available TSPAN1 Antibodies ranked by validation data
- Compare Top TSPAN1 Antibodies
- antibodies-online: Show 5 available TSPAN1 Elisa Kits ranked by validation data
- Compare Top TSPAN1 Elisa Kits
- Quality Products:
- antibodies-online: Show 9 available TSPAN1 Proteins ranked by validation data
- Compare Top TSPAN1 Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for TSPAN1
- Search Santa Cruz Biotechnology (SCBT) for TSPAN1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for TSPAN1
- Horizon Cell Lines for TSPAN1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for TSPAN1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for TSPAN1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for TSPAN1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for TSPAN1
Sources for TSPAN1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB