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Aliases for TSGA10IP Gene

Aliases for TSGA10IP Gene

  • Testis Specific 10 Interacting Protein 2 3 5
  • Tsga10-Interacting Protein 3 4
  • Testis-Specific Protein 10-Interacting Protein 3
  • FAM161C 3

External Ids for TSGA10IP Gene

Previous GeneCards Identifiers for TSGA10IP Gene

  • GC11P065489
  • GC11P065469
  • GC11P065713
  • GC11P062039

Summaries for TSGA10IP Gene

GeneCards Summary for TSGA10IP Gene

TSGA10IP (Testis Specific 10 Interacting Protein) is a Protein Coding gene.

Additional gene information for TSGA10IP Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TSGA10IP Gene

Genomics for TSGA10IP Gene

GeneHancer (GH) Regulatory Elements for TSGA10IP Gene

Promoters and enhancers for TSGA10IP Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I065945 Enhancer 0.8 Ensembl ENCODE 550.8 +0.4 351 1.2 GATAD2A RFX1 FOXA3 CEBPG RARA SP1 SKI POLR2A SCRT2 LOC105369350 TSGA10IP C11orf68 DRAP1 FOSL1 BANF1 EIF1AD CST6 CTSW EFEMP2
GH11I065910 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 10.3 -29.7 -29718 11.4 CLOCK MLX ZFP64 YY1 ZNF213 E2F8 ZNF143 SP3 MEF2D SSRP1 DRAP1 C11orf68 RBM14 LOC105369352 ZFPL1 ENSG00000254461 MUS81 ENSG00000258297 EIF1AD PCNX3
GH11I065886 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 7.6 -50.0 -49987 18.4 CLOCK ZFP64 FEZF1 DMAP1 YY1 SLC30A9 E2F8 ZNF143 ZNF263 SP3 FOSL1 FIBP CCDC85B SNX32 ENSG00000258297 EIF1AD RBM14 MUS81 SART1 POLA2
GH11I065786 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 7.4 -156.8 -156812 4.4 CTCF GTF2F1 PKNOX1 CLOCK FOXA2 SIN3A E2F1 CTBP1 GATA3 POLR2A OVOL1 PIR37328 CATSPER1 KRT8P26 MAP3K11 ZFPL1 ENSG00000258297 MEN1 SYVN1 LOC105369352
GH11I065567 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 4.7 -371.8 -371771 12 MLX FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 SSSCA1 EHBP1L1 FAM89B PCNX3 SF1 EIF1AD POLA2 LOC105369352 NEAT1 ZFPL1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TSGA10IP on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TSGA10IP gene promoter:

Genomic Locations for TSGA10IP Gene

Genomic Locations for TSGA10IP Gene
chr11:65,945,445-65,960,392
(GRCh38/hg38)
Size:
14,948 bases
Orientation:
Plus strand
chr11:65,712,916-65,727,434
(GRCh37/hg19)

Genomic View for TSGA10IP Gene

Genes around TSGA10IP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TSGA10IP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TSGA10IP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TSGA10IP Gene

Proteins for TSGA10IP Gene

  • Protein details for TSGA10IP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q3SY00-T10IP_HUMAN
    Recommended name:
    Testis-specific protein 10-interacting protein
    Protein Accession:
    Q3SY00
    Secondary Accessions:
    • Q3SXZ9
    • Q3SY01
    • Q96M26

    Protein attributes for TSGA10IP Gene

    Size:
    556 amino acids
    Molecular mass:
    62381 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TSGA10IP Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TSGA10IP Gene

Post-translational modifications for TSGA10IP Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TSGA10IP Gene

No data available for DME Specific Peptides for TSGA10IP Gene

Domains & Families for TSGA10IP Gene

Gene Families for TSGA10IP Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for TSGA10IP Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TSGA10IP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TSGA10IP: view

No data available for UniProtKB/Swiss-Prot for TSGA10IP Gene

Function for TSGA10IP Gene

Phenotypes From GWAS Catalog for TSGA10IP Gene

Gene Ontology (GO) - Molecular Function for TSGA10IP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TSGA10IP: view
genes like me logo Genes that share phenotypes with TSGA10IP: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TSGA10IP Gene

Localization for TSGA10IP Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TSGA10IP Gene

Pathways & Interactions for TSGA10IP Gene

SuperPathways for TSGA10IP Gene

No Data Available

Gene Ontology (GO) - Biological Process for TSGA10IP Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TSGA10IP Gene

Drugs & Compounds for TSGA10IP Gene

No Compound Related Data Available

Transcripts for TSGA10IP Gene

mRNA/cDNA for TSGA10IP Gene

(3) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TSGA10IP Gene

Testis specific, 10 interacting protein:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TSGA10IP Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7
SP1: - - - -
SP2: -
SP3:

Relevant External Links for TSGA10IP Gene

GeneLoc Exon Structure for
TSGA10IP
ECgene alternative splicing isoforms for
TSGA10IP

Expression for TSGA10IP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TSGA10IP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TSGA10IP Gene

This gene is overexpressed in Testis (x37.3).

Protein differential expression in normal tissues from HIPED for TSGA10IP Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TSGA10IP Gene



Protein tissue co-expression partners for TSGA10IP Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TSGA10IP Gene:

TSGA10IP

SOURCE GeneReport for Unigene cluster for TSGA10IP Gene:

Hs.350671
genes like me logo Genes that share expression patterns with TSGA10IP: view

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TSGA10IP Gene

Orthologs for TSGA10IP Gene

This gene was present in the common ancestor of chordates.

Orthologs for TSGA10IP Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TSGA10IP 33
  • 97.51 (n)
dog
(Canis familiaris)
Mammalia TSGA10IP 33 34
  • 80.28 (n)
cow
(Bos Taurus)
Mammalia TSGA10IP 33 34
  • 78.8 (n)
mouse
(Mus musculus)
Mammalia Tsga10ip 33 16 34
  • 72.83 (n)
rat
(Rattus norvegicus)
Mammalia Tsga10ip 33
  • 72.13 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia TSGA10IP 34
  • 36 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TSGA10IP 34
  • 24 (a)
OneToOne
Species where no ortholog for TSGA10IP was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TSGA10IP Gene

ENSEMBL:
Gene Tree for TSGA10IP (if available)
TreeFam:
Gene Tree for TSGA10IP (if available)

Paralogs for TSGA10IP Gene

No data available for Paralogs for TSGA10IP Gene

Variants for TSGA10IP Gene

Sequence variations from dbSNP and Humsavar for TSGA10IP Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000018081 -- 65,944,490(+) T/C upstream_transcript_variant
rs1000094545 -- 65,953,449(+) G/C/T intron_variant
rs1000240798 -- 65,957,007(+) G/A genic_downstream_transcript_variant, intron_variant
rs1000451701 -- 65,960,615(+) C/T downstream_transcript_variant
rs1000488526 -- 65,955,536(+) C/T genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for TSGA10IP Gene

Variant ID Type Subtype PubMed ID
esv2667131 CNV deletion 23128226
esv2759834 CNV gain 17122850
esv3626685 CNV loss 21293372
nsv832191 CNV loss 17160897
nsv983036 CNV duplication 23825009

Additional Variant Information for TSGA10IP Gene

Human Gene Mutation Database (HGMD)
TSGA10IP
SNPedia medical, phenotypic, and genealogical associations of SNPs for
TSGA10IP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TSGA10IP Gene

Disorders for TSGA10IP Gene

Additional Disease Information for TSGA10IP

No disorders were found for TSGA10IP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TSGA10IP Gene

Publications for TSGA10IP Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 2 3 4 58
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  4. Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage. (PMID: 25184681) Hill SJ … Livingston DM (Genes & development 2014) 3 58
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58

Products for TSGA10IP Gene

Sources for TSGA10IP Gene

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