Aliases for TSC22D2 Gene

Aliases for TSC22D2 Gene

  • TSC22 Domain Family Member 2 2 3 5
  • TSC22-Related-Inducible Leucine Zipper Protein 4 3 4
  • TSC22 Domain Family Protein 2 3 4
  • TSC22 Domain Family, Member 2 2
  • TSC22 Domain Family 2 3
  • KIAA0669 4
  • TILZ4a 3
  • TILZ4b 3
  • TILZ4c 3
  • TILZ4 4

External Ids for TSC22D2 Gene

Previous GeneCards Identifiers for TSC22D2 Gene

  • GC03P151609
  • GC03P150126
  • GC03P147500

Summaries for TSC22D2 Gene

GeneCards Summary for TSC22D2 Gene

TSC22D2 (TSC22 Domain Family Member 2) is a Protein Coding gene. Diseases associated with TSC22D2 include Keratomalacia. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is TSC22D1.

Additional gene information for TSC22D2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TSC22D2 Gene

Genomics for TSC22D2 Gene

GeneHancer (GH) Regulatory Elements for TSC22D2 Gene

Promoters and enhancers for TSC22D2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TSC22D2 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for TSC22D2

Top Transcription factor binding sites by QIAGEN in the TSC22D2 gene promoter:
  • AREB6
  • Arnt
  • GR
  • GR-alpha
  • GR-beta
  • STAT5B
  • YY1
  • ZID

Genomic Locations for TSC22D2 Gene

Genomic Locations for TSC22D2 Gene
chr3:150,408,335-150,466,431
(GRCh38/hg38)
Size:
58,097 bases
Orientation:
Plus strand
chr3:150,126,122-150,184,218
(GRCh37/hg19)
Size:
58,097 bases
Orientation:
Plus strand

Genomic View for TSC22D2 Gene

Genes around TSC22D2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TSC22D2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TSC22D2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TSC22D2 Gene

Proteins for TSC22D2 Gene

  • Protein details for TSC22D2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O75157-T22D2_HUMAN
    Recommended name:
    TSC22 domain family protein 2
    Protein Accession:
    O75157
    Secondary Accessions:
    • D3DNI5
    • Q6PI50
    • Q9H2Z6
    • Q9H2Z7
    • Q9H2Z8

    Protein attributes for TSC22D2 Gene

    Size:
    780 amino acids
    Molecular mass:
    79228 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA31644.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for TSC22D2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TSC22D2 Gene

Post-translational modifications for TSC22D2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TSC22D2 Gene

Antibody Products

  • Abcam antibodies for TSC22D2

No data available for DME Specific Peptides for TSC22D2 Gene

Domains & Families for TSC22D2 Gene

Gene Families for TSC22D2 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for TSC22D2 Gene

Blocks:
  • TSC-22 / Dip / Bun family
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TSC22D2 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ57127, highly similar to TSC22 domain family protein 2 (B4DMB2_HUMAN)
  • cDNA FLJ51900, highly similar to TSC22 domain family protein 2 (B4DN36_HUMAN)
  • TSC22-related-inducible leucine zipper protein 4 (T22D2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

O75157

UniProtKB/Swiss-Prot:

T22D2_HUMAN :
  • Belongs to the TSC-22/Dip/Bun family.
Family:
  • Belongs to the TSC-22/Dip/Bun family.
genes like me logo Genes that share domains with TSC22D2: view

Function for TSC22D2 Gene

Phenotypes From GWAS Catalog for TSC22D2 Gene

Gene Ontology (GO) - Molecular Function for TSC22D2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific ISM 19274049
GO:0003700 DNA-binding transcription factor activity IEA --
genes like me logo Genes that share ontologies with TSC22D2: view
genes like me logo Genes that share phenotypes with TSC22D2: view

miRNA for TSC22D2 Gene

miRTarBase miRNAs that target TSC22D2