TRX-CAT2-1 Gene (RNA Gene)

TRNA-IMet (Anticodon CAT) 2-1

GC06P027903
GIFtS:
6
Santos and Zasloff (1981) [PubMed 6261953] identified 12 initiator methionine tRNA genes, symbolized tRNA-i(met), in the haploid human genome. Zasloff et al. (1982) [PubMed 6923137] found a variant tRNA-i(met) with a G-to-T transversion in the highly conserved TCGA sequence in loop 4, a sequence position occupied exclusively by a purine (usually G) in almost 200 prokaryotic and... See more...

Aliases for TRX-CAT2-1 Gene

Subcategory (RNA class) for TRX-CAT2-1 Gene

tRNA

Quality Score for this RNA gene is

13

Aliases for TRX-CAT2-1 Gene

  • TRNA-IMet (Anticodon CAT) 2-1 2 3
  • Transfer RNA Methionine Initiator 1 (Anticodon CAU) 2 3
  • Transfer RNA Initiator Methionine (CAT) 2-1 2 3
  • Transfer RNA Methionine 2 (Anticodon CAU) 2 3
  • Transfer RNA-IMet (CAT) 2-1 2 3
  • TRNA-IMet-CAT-2-1 3 167
  • TRNA Methionine Initiator 1 3
  • TRX-CAT2-1 2
  • TRNAMI2 3
  • TRNAMI1 3
  • RF00005 174
  • RNTMI2 3
  • TRNAM2 3
  • RNTMI 3
  • TRMI1 3
  • TRM1 3

External Ids for TRX-CAT2-1 Gene

Previous HGNC Symbols for TRX-CAT2-1 Gene

  • TRM1
  • TRMI1
  • TRNAMI1
  • TRNAM2

Previous GeneCards Identifiers for TRX-CAT2-1 Gene

  • GC06P027781
  • GC06P027785
  • GC06P027811
  • GC06P027812
  • GC06P027787
  • GC06P027789
  • GC06P027793
  • GC06P027795
  • GC06P027797
  • GC06P027801
  • GC06P027803
  • GC06P027806

Summaries for TRX-CAT2-1 Gene

Entrez Gene Summary for TRX-CAT2-1 Gene

  • Santos and Zasloff (1981) [PubMed 6261953] identified 12 initiator methionine tRNA genes, symbolized tRNA-i(met), in the haploid human genome. Zasloff et al. (1982) [PubMed 6923137] found a variant tRNA-i(met) with a G-to-T transversion in the highly conserved TCGA sequence in loop 4, a sequence position occupied exclusively by a purine (usually G) in almost 200 prokaryotic and eukaryotic tRNAs. One functional consequence of this base substitution is reduction in the rate of processing of the primary transcript of the gene. A second, demonstrated by microinjection into the germinal vesicle of the intact Xenopus laevis oocyte, is blockage of egress from the nucleus. It has been estimated that the human haploid genome contains 1,000 to 2,000 tRNA genes and that there are 50 to 60 chromatographically distinct tRNA species. These observations suggest redundancy of some tRNA genes. The studies of initiator methionine tRNA genes bear out this suspicion.[supplied by OMIM, Sep 2009]

GeneCards Summary for TRX-CAT2-1 Gene

TRX-CAT2-1 (TRNA-IMet (Anticodon CAT) 2-1) is an RNA Gene, and is affiliated with the tRNA class.

Rfam classification for TRX-CAT2-1 Gene

Additional gene information for TRX-CAT2-1 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for TRX-CAT2-1 Gene

Genomics for TRX-CAT2-1 Gene

GeneHancer (GH) Regulatory Elements for TRX-CAT2-1 Gene

Promoters and enhancers for TRX-CAT2-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH06J027776 Enhancer 1.1 FANTOM5 ENCODE 750.6 -0.2 -242 1.7 GTF3C2 ZNF24 ZBTB40 SMARCE1 CC2D1A ELF1 RBM39 TEAD4 ZNF148 CSDE1 TRX-CAT2-1 piR-30961-007 piR-33437-008 ZKSCAN8 ZSCAN12 ZKSCAN3 ZKSCAN4 ZSCAN9 ZSCAN23 ZNF603P
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TRX-CAT2-1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRX-CAT2-1 Gene

Genomic Locations for TRX-CAT2-1 Gene
chr6:27,777,885-27,777,956
(GRCh38/hg38)
Size:
72 bases
Orientation:
Plus strand
chr6:27,745,664-27,745,735
(GRCh37/hg19)
Size:
72 bases
Orientation:
Plus strand

Genomic View for TRX-CAT2-1 Gene

Genes around TRX-CAT2-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRX-CAT2-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRX-CAT2-1 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for TRX-CAT2-1 Gene

Proteins for TRX-CAT2-1 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for TRX-CAT2-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRX-CAT2-1 Gene

Domains & Families for TRX-CAT2-1 Gene

Gene Families for TRX-CAT2-1 Gene

HGNC:
genes like me logo Genes that share domains with TRX-CAT2-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TRX-CAT2-1 Gene

Function for TRX-CAT2-1 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRX-CAT2-1 Gene

Localization for TRX-CAT2-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRX-CAT2-1 Gene

Pathways & Interactions for TRX-CAT2-1 Gene

PathCards logo

SuperPathways for TRX-CAT2-1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TRX-CAT2-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRX-CAT2-1 Gene

Drugs & Compounds for TRX-CAT2-1 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for TRX-CAT2-1 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for TRX-CAT2-1 Gene

(1) RNACentral transcripts :
(2) ENA transcripts :
(2) GtRNAdb transcripts :
(1) Rfam transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRX-CAT2-1 Gene

No ASD Table

Relevant External Links for TRX-CAT2-1 Gene

GeneLoc Exon Structure for
TRX-CAT2-1
ECgene alternative splicing isoforms for
TRX-CAT2-1

Expression for TRX-CAT2-1 Gene

Products:

  1. Primer
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRX-CAT2-1 Gene

Orthologs for TRX-CAT2-1 Gene

No data available for Orthologs and Evolution for TRX-CAT2-1 Gene

Paralogs for TRX-CAT2-1 Gene

No data available for Paralogs for TRX-CAT2-1 Gene

Variants for TRX-CAT2-1 Gene

Additional Variant Information for TRX-CAT2-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRX-CAT2-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRX-CAT2-1 Gene

Disorders for TRX-CAT2-1 Gene

No disorders were found for TRX-CAT2-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRX-CAT2-1 Gene

Publications for TRX-CAT2-1 Gene

  1. Comparative analysis of human chromosomal segments bearing nonallelic dispersed tRNAimet genes. (PMID: 6261953) Santos T … Zasloff M (Cell 1981) 2 3 56
  2. GtRNAdb: a database of transfer RNA genes detected in genomic sequence. (PMID: 18984615) Chan PP … Lowe TM (Nucleic acids research 2009) 3 56
  3. Two nonallelic tRNAiMet genes are located in the p23 leads to q12 region of human chromosome 6. (PMID: 6308668) Naylor SL … Zasloff M (Proceedings of the National Academy of Sciences of the United States of America 1983) 3 56
  4. Impaired nuclear transport of a human variant tRNAiMet. (PMID: 6923137) Zasloff M … Santos T (Nature 1982) 3 56

ExternalLinks

View latest publications for TRX-CAT2-1 gene in Mastermind

Products for TRX-CAT2-1 Gene

Sources for TRX-CAT2-1 Gene