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TRX-CAT2-1 Gene(RNA Gene)

Transfer RNA-IMet (CAT) 2-1

GCID:
GC06P027801
GIFtS:
8
Genes Participants
UDN Logo

Aliases for TRX-CAT2-1 Gene

Subcategory (RNA class) for TRX-CAT2-1 Gene

tRNA

Quality Score for this RNA gene is

2

Aliases for TRX-CAT2-1 Gene

  • Transfer RNA-IMet (CAT) 2-1 2 3
  • Transfer RNA Methionine Initiator 1 (Anticodon CAU) 2 3
  • Transfer RNA Initiator Methionine (CAT) 2-1 2 3
  • Transfer RNA Methionine 2 (Anticodon CAU) 2 3
  • TRNA Methionine Initiator 1 3
  • TRNA-IMet-CAT-2-1 3
  • TRNAMI2 3
  • TRNAMI1 3
  • RNTMI2 3
  • TRNAM2 3
  • RNTMI 3
  • TRMI1 3
  • TRM1 3

External Ids for TRX-CAT2-1 Gene

ORGUL Members for TRX-CAT2-1 Gene

Previous HGNC Symbols for TRX-CAT2-1 Gene

  • TRM1
  • TRMI1
  • TRNAMI1
  • TRNAM2

Previous GeneCards Identifiers for TRX-CAT2-1 Gene

  • GC06P027781
  • GC06P027785
  • GC06P027787
  • GC06P027789
  • GC06P027793
  • GC06P027795
  • GC06P027797

Summaries for TRX-CAT2-1 Gene

Entrez Gene Summary for TRX-CAT2-1 Gene

  • Santos and Zasloff (1981) [PubMed 6261953] identified 12 initiator methionine tRNA genes, symbolized tRNA-i(met), in the haploid human genome. Zasloff et al. (1982) [PubMed 6923137] found a variant tRNA-i(met) with a G-to-T transversion in the highly conserved TCGA sequence in loop 4, a sequence position occupied exclusively by a purine (usually G) in almost 200 prokaryotic and eukaryotic tRNAs. One functional consequence of this base substitution is reduction in the rate of processing of the primary transcript of the gene. A second, demonstrated by microinjection into the germinal vesicle of the intact Xenopus laevis oocyte, is blockage of egress from the nucleus. It has been estimated that the human haploid genome contains 1,000 to 2,000 tRNA genes and that there are 50 to 60 chromatographically distinct tRNA species. These observations suggest redundancy of some tRNA genes. The studies of initiator methionine tRNA genes bear out this suspicion.[supplied by OMIM, Sep 2009]

GeneCards Summary for TRX-CAT2-1 Gene

TRX-CAT2-1 (Transfer RNA-IMet (CAT) 2-1) is an RNA Gene, and is affiliated with the tRNA class.

Additional gene information for TRX-CAT2-1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRX-CAT2-1 Gene

Genomics for TRX-CAT2-1 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for TRX-CAT2-1 Gene

Promoters and enhancers for TRX-CAT2-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH06I027776 Enhancer 1.2 FANTOM5 ENCODE 550.8 -0.2 -242 1.7 ARNT YY1 GTF3C2 ZNF766 E2F8 ARID2 RUNX3 NCOA1 ZNF592 MEF2D GC06P027803 PIR58221 TRX-CAT2-1 ZKSCAN8 ZSCAN12 ZKSCAN3 ZNF603P ZSCAN23 ZSCAN9 HIST1H4PS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRX-CAT2-1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRX-CAT2-1 Gene

Genomic Locations for TRX-CAT2-1 Gene
chr6:27,777,885-27,777,956
(GRCh38/hg38)
Size:
72 bases
Orientation:
Plus strand
chr6:27,745,664-27,745,735
(GRCh37/hg19)

Genomic View for TRX-CAT2-1 Gene

Genes around TRX-CAT2-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRX-CAT2-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRX-CAT2-1 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for TRX-CAT2-1 Gene

Proteins for TRX-CAT2-1 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for TRX-CAT2-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRX-CAT2-1 Gene

Domains & Families for TRX-CAT2-1 Gene

Gene Families for TRX-CAT2-1 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRX-CAT2-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRX-CAT2-1 Gene

Function for TRX-CAT2-1 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRX-CAT2-1 Gene

Localization for TRX-CAT2-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRX-CAT2-1 Gene

Pathways & Interactions for TRX-CAT2-1 Gene

SuperPathways for TRX-CAT2-1 Gene

PathCards logo More details on SuperPathways for TRX-CAT2-1
No Data Available

Interacting Proteins for TRX-CAT2-1 Gene

Gene Ontology (GO) - Biological Process for TRX-CAT2-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRX-CAT2-1 Gene

Drugs & Compounds for TRX-CAT2-1 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for TRX-CAT2-1 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRX-CAT2-1 Gene

No ASD Table

Relevant External Links for TRX-CAT2-1 Gene

GeneLoc Exon Structure for
TRX-CAT2-1
ECgene alternative splicing isoforms for
TRX-CAT2-1

No data available for mRNA/cDNA for TRX-CAT2-1 Gene

Expression for TRX-CAT2-1 Gene

Products:

  1. Primer
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRX-CAT2-1 Gene

Orthologs for TRX-CAT2-1 Gene

No data available for Orthologs and Evolution for TRX-CAT2-1 Gene

Paralogs for TRX-CAT2-1 Gene

No data available for Paralogs for TRX-CAT2-1 Gene

Variants for TRX-CAT2-1 Gene

Additional Variant Information for TRX-CAT2-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRX-CAT2-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRX-CAT2-1 Gene

Disorders for TRX-CAT2-1 Gene

No disorders were found for TRX-CAT2-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRX-CAT2-1 Gene

Publications for TRX-CAT2-1 Gene

  1. Comparative analysis of human chromosomal segments bearing nonallelic dispersed tRNAimet genes. (PMID: 6261953) Santos T … Zasloff M (Cell 1981) 2 3 58
  2. GtRNAdb: a database of transfer RNA genes detected in genomic sequence. (PMID: 18984615) Chan PP … Lowe TM (Nucleic acids research 2009) 3 58
  3. Two nonallelic tRNAiMet genes are located in the p23 leads to q12 region of human chromosome 6. (PMID: 6308668) Naylor SL … Zasloff M (Proceedings of the National Academy of Sciences of the United States of America 1983) 3 58
  4. Impaired nuclear transport of a human variant tRNAiMet. (PMID: 6923137) Zasloff M … Santos T (Nature 1982) 3 58

Products for TRX-CAT2-1 Gene

Sources for TRX-CAT2-1 Gene

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