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Aliases for TRPV6 Gene

Aliases for TRPV6 Gene

  • Transient Receptor Potential Cation Channel Subfamily V Member 6 2 3 5
  • Epithelial Calcium Channel 2 2 3 4
  • Calcium Transport Protein 1 3 4
  • ECAC2 3 4
  • CAT1 3 4
  • Transient Receptor Potential Cation Channel, Subfamily V, Member 6 2
  • Epithelial Apical Membrane Calcium Transporter/Channel CaT1 3
  • Alu-Binding Protein With Zinc Finger Domain 3
  • Calcium Transporter-Like Protein 3
  • HSA277909 3
  • CaT-Like 4
  • ABP/ZF 3
  • LP6728 3
  • CaT-L 4
  • TrpV6 4
  • CATL 3
  • ZFAB 3

External Ids for TRPV6 Gene

Previous HGNC Symbols for TRPV6 Gene

  • ECAC2

Previous GeneCards Identifiers for TRPV6 Gene

  • GC07U990280
  • GC07M140894
  • GC07M141963
  • GC07M142039
  • GC07M142085
  • GC07M142279
  • GC07M142568
  • GC07M136907

Summaries for TRPV6 Gene

Entrez Gene Summary for TRPV6 Gene

  • This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds. [provided by RefSeq, Feb 2015]

GeneCards Summary for TRPV6 Gene

TRPV6 (Transient Receptor Potential Cation Channel Subfamily V Member 6) is a Protein Coding gene. Diseases associated with TRPV6 include Prostate Cancer and Aromatase Deficiency. Among its related pathways are Mineral absorption and CREB Pathway. Gene Ontology (GO) annotations related to this gene include calmodulin binding and calcium channel activity. An important paralog of this gene is TRPV5.

UniProtKB/Swiss-Prot for TRPV6 Gene

  • Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine (PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin (By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification (PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.

Tocris Summary for TRPV6 Gene

  • Vanilloids are a group of compounds, structurally related to capsaicin, thought to exert their actions via vanilloid receptors. The vanilloid receptor family (TRPV) is a member of the transient receptor potential (TRP) superfamily of ion channels, and have six members (TRPV1-6).

Gene Wiki entry for TRPV6 Gene

Additional gene information for TRPV6 Gene

No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRPV6 Gene

Genomics for TRPV6 Gene

GeneHancer (GH) Regulatory Elements for TRPV6 Gene

Promoters and enhancers for TRPV6 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I142885 Promoter/Enhancer 0.9 EPDnew ENCODE 555.2 -0.1 -75 1 MAZ POLR2A GLIS1 TRPV6 ENSG00000224970 TRPV5
GH07I142805 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 10.8 +77.0 77025 5.7 HDGF PKNOX1 SMAD1 IRF4 NCOA2 TCF12 GATA2 ZNF143 ATF7 FOS TRBV30 TRPV6 GSTK1 EPHB6 TCAF1P1 TRPV5 CASP2 GC07M142813 TRBC2 TRB
GH07I143282 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE 5.9 -400.8 -400785 7.1 HDGF FOXA2 PKNOX1 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 CASP2 GC07M143288 PIR32183 LOC105375545 TMEM139 LOC154761 RN7SL535P ZYX TRPV6
GH07I142811 Enhancer 1.1 Ensembl ENCODE dbSUPER 10 +72.6 72564 2.6 KLF1 FOXA2 EBF1 TEAD3 FOSL1 CTBP1 GATA3 POLR2A RCOR1 FOS TRBV30 GC07M142813 LOC105375541 TRPV6 EPHB6 TRBV7-3 TRPV5 TRB
GH07I142796 Promoter/Enhancer 1.1 Ensembl dbSUPER 4.6 +88.6 88561 1.2 SMAD1 KLF5 POLR2A IKZF1 ID3 NBN MLLT1 EZH2 TRBD2 TRBJ2-1 TRBJ2-2 TRBJ2-2P TRBJ2-3 TRBJ2-4 TRBJ2-5 TRBJ2-6 TRBJ2-7 PRSS3P1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRPV6 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TRPV6 gene promoter:

Genomic Locations for TRPV6 Gene

Genomic Locations for TRPV6 Gene
chr7:142,871,203-142,885,762
(GRCh38/hg38)
Size:
14,560 bases
Orientation:
Minus strand
chr7:142,568,956-142,583,507
(GRCh37/hg19)

Genomic View for TRPV6 Gene

Genes around TRPV6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRPV6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRPV6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRPV6 Gene

Proteins for TRPV6 Gene

  • Protein details for TRPV6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H1D0-TRPV6_HUMAN
    Recommended name:
    Transient receptor potential cation channel subfamily V member 6
    Protein Accession:
    Q9H1D0
    Secondary Accessions:
    • A4D2I8
    • Q8TDL3
    • Q8WXR8
    • Q96LC5
    • Q9H1D1
    • Q9H296

    Protein attributes for TRPV6 Gene

    Size:
    765 amino acids
    Molecular mass:
    87286 Da
    Quaternary structure:
    • Homotetramer and probably heterotetramer with TRPV5. Interacts with TRPV5. Interacts with S100A10 and probably with the ANAX2-S100A10 heterotetramer. The interaction with S100A10 is required for the trafficking to the plasma membrane. Interacts with BSPRY (By similarity). Interacts with TCAF1 and TCAF2 isoform 2 (PubMed:25559186). Interacts with calmodulin (PubMed:11248124).
    SequenceCaution:
    • Sequence=AAK50426.1; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical ACG threonine codon.; Evidence={ECO:0000305 PubMed:23612980}; Sequence=AAL40230.1; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical ACG threonine codon.; Evidence={ECO:0000305 PubMed:23612980}; Sequence=AAM00356.1; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical ACG threonine codon.; Evidence={ECO:0000305 PubMed:23612980}; Sequence=AAO38052.1; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical ACG threonine codon.; Evidence={ECO:0000305 PubMed:23612980}; Sequence=BAF84396.1; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical ACG threonine codon.; Evidence={ECO:0000305 PubMed:23612980}; Sequence=CAC20416.2; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical ACG threonine codon.; Evidence={ECO:0000305 PubMed:23612980}; Sequence=CAC20417.2; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical ACG threonine codon.; Evidence={ECO:0000305 PubMed:23612980}; Sequence=CAD32311.1; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical ACG threonine codon.; Evidence={ECO:0000305 PubMed:23612980};

    Alternative splice isoforms for TRPV6 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TRPV6 Gene

Post-translational modifications for TRPV6 Gene

  • Glycosylated.
  • Phosphorylation at Tyr-201 by SRC leads to an increased calcium influx through the channel. Probably dephosphorylated at this site by PTPN1 (By similarity). Phosphorylation by PRKCA at the calmodulin binding site delays channel inactivation (PubMed:11248124).
  • Glycosylation at posLast=398398

Other Protein References for TRPV6 Gene

No data available for DME Specific Peptides for TRPV6 Gene

Domains & Families for TRPV6 Gene

Gene Families for TRPV6 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Transporters
  • Voltage-gated ion channels

Graphical View of Domain Structure for InterPro Entry

Q9H1D0

UniProtKB/Swiss-Prot:

TRPV6_HUMAN :
  • Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV6 sub-subfamily.
Family:
  • Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV6 sub-subfamily.
genes like me logo Genes that share domains with TRPV6: view

Function for TRPV6 Gene

Molecular function for TRPV6 Gene

UniProtKB/Swiss-Prot Function:
Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine (PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin (By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification (PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.

Phenotypes From GWAS Catalog for TRPV6 Gene

Gene Ontology (GO) - Molecular Function for TRPV6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005262 calcium channel activity TAS --
GO:0005515 protein binding IPI 15894168
GO:0005516 calmodulin binding IEA,IDA 11278579
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with TRPV6: view
genes like me logo Genes that share phenotypes with TRPV6: view

miRNA for TRPV6 Gene

miRTarBase miRNAs that target TRPV6

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TRPV6 Gene

Localization for TRPV6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRPV6 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TRPV6 gene
Compartment Confidence
plasma membrane 5
extracellular 5
nucleus 1
cytosol 1

Gene Ontology (GO) - Cellular Components for TRPV6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane TAS 11278579
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0070062 extracellular exosome HDA,IDA 23376485
genes like me logo Genes that share ontologies with TRPV6: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for TRPV6 Gene

Pathways & Interactions for TRPV6 Gene

genes like me logo Genes that share pathways with TRPV6: view

Pathways by source for TRPV6 Gene

SIGNOR curated interactions for TRPV6 Gene

Is inactivated by:

Gene Ontology (GO) - Biological Process for TRPV6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA --
GO:0006811 ion transport IEA --
GO:0006816 calcium ion transport NAS 11278579
GO:0017158 regulation of calcium ion-dependent exocytosis NAS 11278579
GO:0034220 ion transmembrane transport IEA --
genes like me logo Genes that share ontologies with TRPV6: view

Drugs & Compounds for TRPV6 Gene

(16) Drugs for TRPV6 Gene - From: DrugBank, DGIdb, IUPHAR, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
calcium Approved Nutra 0
Calcium Citrate Approved Pharma Transporter, substrate 0
Calcium Phosphate Approved Pharma Transporter, substrate 0
2-APB Pharma Antagonist, Pore Blocker IP3 receptor antagonist. Also TRP channel modulator 0
Cd<sup>2+</sup> Pharma Channel blocker 0

(5) Additional Compounds for TRPV6 Gene - From: Novoseek and Tocris

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
(E)-Capsaicin
404-86-4

(5) Tocris Compounds for TRPV6 Gene

Compound Action Cas Number
(E)-Capsaicin Prototypic vanilloid receptor agonist 404-86-4
Capsazepine Vanilloid receptor antagonist; also activator of ENaCdelta 138977-28-3
Olvanil Potent vanilloid receptor agonist 58493-49-5
Resiniferatoxin Potent vanilloid receptor agonist 57444-62-9
STEARDA Endogenous lipid, active in vivo. Enhances effects of endovanilloids at TRPV1 receptors 105955-10-0
genes like me logo Genes that share compounds with TRPV6: view

Transcripts for TRPV6 Gene

mRNA/cDNA for TRPV6 Gene

(2) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRPV6 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b
SP1: - -
SP2:
SP3:

Relevant External Links for TRPV6 Gene

GeneLoc Exon Structure for
TRPV6
ECgene alternative splicing isoforms for
TRPV6

Expression for TRPV6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRPV6 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TRPV6 Gene

This gene is overexpressed in Pancreas (x19.0) and Prostate (x8.5).

Protein differential expression in normal tissues from HIPED for TRPV6 Gene

This gene is overexpressed in Placenta (45.1), Heart (12.2), and Urine (11.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TRPV6 Gene



Protein tissue co-expression partners for TRPV6 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRPV6 Gene:

TRPV6

SOURCE GeneReport for Unigene cluster for TRPV6 Gene:

Hs.302740

mRNA Expression by UniProt/SwissProt for TRPV6 Gene:

Q9H1D0-TRPV6_HUMAN
Tissue specificity: Expressed at high levels in the gastrointestinal tract, including esophagus, stomach, duodenum, jejunum, ileum and colon, and in pancreas, placenta, prostate and salivary gland. Expressed at moderate levels in liver, kidney and testis. Expressed in trophoblasts of placenta villus trees (at protein level)(PubMed:23612980). Expressed in locally advanced prostate cancer, metastatic and androgen-insensitive prostatic lesions but not detected in healthy prostate tissue and benign prostatic hyperplasia.

Evidence on tissue expression from TISSUES for TRPV6 Gene

  • Kidney(4.5)
  • Intestine(2.9)
genes like me logo Genes that share expression patterns with TRPV6: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for TRPV6 Gene

Orthologs for TRPV6 Gene

This gene was present in the common ancestor of animals.

Orthologs for TRPV6 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TRPV6 33 34
  • 99.45 (n)
dog
(Canis familiaris)
Mammalia TRPV6 33 34
  • 88.44 (n)
mouse
(Mus musculus)
Mammalia Trpv6 33 16 34
  • 86.46 (n)
rat
(Rattus norvegicus)
Mammalia Trpv6 33
  • 86.42 (n)
cow
(Bos Taurus)
Mammalia TRPV6 33 34
  • 86.08 (n)
oppossum
(Monodelphis domestica)
Mammalia TRPV6 34
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 62 (a)
OneToMany
-- 34
  • 58 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 34
  • 70 (a)
OneToMany
TRPV6 33
  • 69.33 (n)
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 69 (a)
ManyToMany
-- 34
  • 69 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia trpv5 33
  • 64.06 (n)
African clawed frog
(Xenopus laevis)
Amphibia XCAT1 33
zebrafish
(Danio rerio)
Actinopterygii trpv6 33 34
  • 58.18 (n)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.7984 33
fruit fly
(Drosophila melanogaster)
Insecta nan 34
  • 21 (a)
ManyToMany
iav 34
  • 14 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea ocr-4 35 34
  • 27 (a)
osm-9 35 34
  • 25 (a)
ocr-1 34
  • 19 (a)
ManyToMany
ocr-2 34
  • 18 (a)
ManyToMany
ocr-3 34
  • 18 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 25 (a)
ManyToMany
-- 34
  • 22 (a)
ManyToMany
Species where no ortholog for TRPV6 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TRPV6 Gene

ENSEMBL:
Gene Tree for TRPV6 (if available)
TreeFam:
Gene Tree for TRPV6 (if available)

Paralogs for TRPV6 Gene

Paralogs for TRPV6 Gene

(4) SIMAP similar genes for TRPV6 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with TRPV6: view

Variants for TRPV6 Gene

Sequence variations from dbSNP and Humsavar for TRPV6 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs387907545 uncertain-significance, not provided 142,877,718(-) G/A coding_sequence_variant, synonymous_variant
rs387907546 uncertain-significance, not provided 142,874,505(-) T/C/G coding_sequence_variant, missense_variant
rs387907547 uncertain-significance, not provided 142,874,600(-) C/G/T coding_sequence_variant, missense_variant
rs387907548 uncertain-significance, not provided 142,873,452(-) G/T coding_sequence_variant, missense_variant
rs1000394543 -- 142,885,596(-) C/T coding_sequence_variant, missense_variant

Structural Variations from Database of Genomic Variants (DGV) for TRPV6 Gene

Variant ID Type Subtype PubMed ID
nsv949965 CNV deletion 24416366
nsv831168 CNV gain 17160897
nsv608656 CNV loss 21841781
nsv526015 CNV gain 19592680
nsv520735 CNV loss 19592680
nsv428187 CNV loss 18775914
nsv1030700 CNV gain 25217958
esv2759569 CNV loss 17122850

Variation tolerance for TRPV6 Gene

Residual Variation Intolerance Score: 23.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.99; 84.10% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TRPV6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRPV6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRPV6 Gene

Disorders for TRPV6 Gene

MalaCards: The human disease database

(5) MalaCards diseases for TRPV6 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
prostate cancer
  • prostate cancer, susceptibility to
aromatase deficiency
  • pseudohermaphroditism, female, due to placental aromatase deficiency
corneal staphyloma
chromosomal deletion syndrome
osmotic diarrhea
- elite association - COSMIC cancer census association via MalaCards
Search TRPV6 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for TRPV6

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with TRPV6: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TRPV6 Gene

Publications for TRPV6 Gene

  1. Structural conservation of the genes encoding CaT1, CaT2, and related cation channels. (PMID: 11549322) Peng JB … Hediger MA (Genomics 2001) 2 3 4 22 58
  2. TRPV6 alleles do not influence prostate cancer progression. (PMID: 19857260) Kessler T … Flockerzi V (BMC cancer 2009) 3 22 44 58
  3. TRPV6 exhibits unusual patterns of polymorphism and divergence in worldwide populations. (PMID: 16717058) Akey JM … Shriver MD (Human molecular genetics 2006) 2 3 22 58
  4. Competitive regulation of CaT-like-mediated Ca2+ entry by protein kinase C and calmodulin. (PMID: 11248124) Niemeyer BA … Trost C (Proceedings of the National Academy of Sciences of the United States of America 2001) 3 4 22 58
  5. Expression of CaT-like, a novel calcium-selective channel, correlates with the malignancy of prostate cancer. (PMID: 11278579) Wissenbach U … Flockerzi V (The Journal of biological chemistry 2001) 3 4 22 58

Products for TRPV6 Gene

Sources for TRPV6 Gene

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