Aliases for TRPM2-AS Gene

Subcategory (RNA class) for TRPM2-AS Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for TRPM2-AS Gene

  • TRPM2 Antisense RNA 2 3 5
  • TRPM2-AS 2 168
  • HSALNG0133533 167
  • NONHSAG033027 92
  • TRPM2-AS1 3

External Ids for TRPM2-AS Gene

Previous GeneCards Identifiers for TRPM2-AS Gene

  • GC21M045837

Summaries for TRPM2-AS Gene

GeneCards Summary for TRPM2-AS Gene

TRPM2-AS (TRPM2 Antisense RNA) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with TRPM2-AS include Prostate Cancer and Lung Cancer.

Additional gene information for TRPM2-AS Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for TRPM2-AS Gene

Genomics for TRPM2-AS Gene

GeneHancer (GH) Regulatory Elements for TRPM2-AS Gene

Promoters and enhancers for TRPM2-AS Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21J044424 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE CraniofacialAtlas 500.7 -0.3 -310 2.2 POLR2A GABPA SMARCC1 CEBPB RCOR1 ZFHX2 GTF2F1 MAX MXI1 FOXP2 TRPM2 TRPM2-AS CFAP410 piR-35674-329
GH21J044223 Enhancer 0.8 Ensembl ENCODE 6.1 +202.7 202695 2.6 ZIC2 ZNF316 MAFF POLR2A TARDBP MAFK FOXA1 MAFG MTA3 KLF1 piR-43105-409 GATD3A PWP2 ICOSLG TRPM2-AS PICSAR lnc-DNMT3L-1
GH21J044285 Promoter 0.9 EPDnew Ensembl 5.1 +139.8 139795 0.4 MAZ EZH2 SUZ12 ZNF770 AIRE TRPM2-AS piR-52261-169
GH21J044428 Enhancer 0.8 Ensembl ENCODE 0.7 -3.3 -3274 0.3 ZNF263 ZNF341 MBD2 ZBTB17 POLR2A CHD2 KLF8 SKIL PKNOX1 IRF1 piR-35674-329 TRPM2-AS TRPM2
GH21J044427 Enhancer 0.8 Ensembl ENCODE 0.7 -2.6 -2618 0.8 ZNF263 ZNF341 MBD2 ZBTB17 POLR2A CHD2 KLF8 SKIL PKNOX1 IRF1 piR-35674-329 TRPM2-AS TRPM2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around TRPM2-AS on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRPM2-AS Gene

Genomic Locations for TRPM2-AS Gene
chr21:44,401,911-44,425,596
(GRCh38/hg38)
Size:
23,686 bases
Orientation:
Minus strand
chr21:45,834,473-45,845,155
(GRCh37/hg19)
Size:
10,683 bases
Orientation:
Minus strand

Genomic View for TRPM2-AS Gene

Genes around TRPM2-AS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRPM2-AS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRPM2-AS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRPM2-AS Gene

Proteins for TRPM2-AS Gene

Post-translational modifications for TRPM2-AS Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRPM2-AS Gene

Domains & Families for TRPM2-AS Gene

Gene Families for TRPM2-AS Gene

genes like me logo Genes that share domains with TRPM2-AS: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for TRPM2-AS Gene

Function for TRPM2-AS Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRPM2-AS Gene

Localization for TRPM2-AS Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TRPM2-AS gene
Compartment Confidence
plasma membrane 1
extracellular 1
mitochondrion 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRPM2-AS Gene

Pathways & Interactions for TRPM2-AS Gene

PathCards logo

SuperPathways for TRPM2-AS Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for TRPM2-AS Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for TRPM2-AS Gene

Drugs & Compounds for TRPM2-AS Gene

No Compound Related Data Available

Transcripts for TRPM2-AS Gene

mRNA/cDNA for TRPM2-AS Gene

12 RNACentral transcripts :
1 REFSEQ mRNAs :
2 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 NONCODE transcripts :
3 LncBook transcripts :
10 LNCipedia transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for TRPM2-AS Gene

No ASD Table

Relevant External Links for TRPM2-AS Gene

GeneLoc Exon Structure for
TRPM2-AS

Expression for TRPM2-AS Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TRPM2-AS Gene

mRNA differential expression in normal tissues according to GTEx for TRPM2-AS Gene

This gene is overexpressed in Spleen (x8.0) and Testis (x4.2).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for TRPM2-AS

genes like me logo Genes that share expression patterns with TRPM2-AS: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRPM2-AS Gene

Orthologs for TRPM2-AS Gene

Evolution for TRPM2-AS Gene

ENSEMBL:
Gene Tree for TRPM2-AS (if available)
TreeFam:
Gene Tree for TRPM2-AS (if available)

No data available for Orthologs for TRPM2-AS Gene

Paralogs for TRPM2-AS Gene

No data available for Paralogs for TRPM2-AS Gene

Variants for TRPM2-AS Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for TRPM2-AS Gene

SNP ID Clinical significance and condition Chr 21 pos Variation AA Info Type
726111 Likely Benign: not provided 44,423,740(-) C/T INTRON_VARIANT
777552 Benign: not provided 44,424,868(-) A/. MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
rs746629167 Uncertain Significance: not provided 44,418,501(-) G/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT

Additional dbSNP identifiers (rs#s) for TRPM2-AS Gene

Structural Variations from Database of Genomic Variants (DGV) for TRPM2-AS Gene

Variant ID Type Subtype PubMed ID
esv2723638 CNV deletion 23290073
esv2723655 CNV deletion 23290073
esv33817 CNV loss 17666407
nsv1058359 CNV gain 25217958
nsv509800 CNV insertion 20534489
nsv519245 CNV loss 19592680
nsv587740 CNV loss 21841781
nsv587781 CNV loss 21841781
nsv587801 CNV loss 21841781
nsv953646 CNV deletion 24416366

Additional Variant Information for TRPM2-AS Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRPM2-AS

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TRPM2-AS Gene

Disorders for TRPM2-AS Gene

MalaCards: The human disease database

(2) MalaCards diseases for TRPM2-AS Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
prostate cancer
  • prostate cancer, somatic
lung cancer
  • adenocarcinoma of lung
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for TRPM2-AS

genes like me logo Genes that share disorders with TRPM2-AS: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TRPM2-AS Gene

Publications for TRPM2-AS Gene

  1. Downregulated long non-coding RNA TRPM2-AS inhibits cisplatin resistance of non-small cell lung cancer cells via activation of p53- p66shc pathway. (PMID: 28678322) Ma LY … Wang HY (European review for medical and pharmacological sciences 2017) 2 3 54
  2. Antisense transcription at the TRPM2 locus as a novel prognostic marker and therapeutic target in prostate cancer. (PMID: 24931166) Orfanelli U … Lavorgna G (Oncogene 2015) 2 3 54
  3. Identification of novel sense and antisense transcription at the TRPM2 locus in cancer. (PMID: 18957938) Orfanelli U … Lavorgna G (Cell research 2008) 2 3 54
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 54

Products for TRPM2-AS Gene

Sources for TRPM2-AS Gene